1AIL
 
 | | N-TERMINAL FRAGMENT OF NS1 PROTEIN FROM INFLUENZA A VIRUS | | 分子名称: | NONSTRUCTURAL PROTEIN NS1 | | 著者 | Liu, J, Lynch, P.A, Chien, C, Montelione, G.T, Krug, R.M, Berman, H.M. | | 登録日 | 1997-04-21 | | 公開日 | 1997-10-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the unique RNA-binding domain of the influenza virus NS1 protein.
Nat.Struct.Biol., 4, 1997
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3C4B
 | | Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | | 分子名称: | Endoribonuclease Dicer | | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | | 登録日 | 2008-01-29 | | 公開日 | 2008-02-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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6A4P
 | | HEWL crystals soaked in 2.5M GuHCl for 40 minutes | | 分子名称: | CHLORIDE ION, GUANIDINE, Lysozyme C, ... | | 著者 | Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V. | | 登録日 | 2018-06-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122, 2019
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1BDG
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1BFP
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1BG3
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3C4T
 | | Structure of RNaseIIIb and dsRNA binding domains of mouse Dicer | | 分子名称: | CADMIUM ION, Endoribonuclease Dicer | | 著者 | Lee, J.K, Du, Z, Tjhen, R.J, Stroud, R.M, James, T.L. | | 登録日 | 2008-01-30 | | 公開日 | 2008-02-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and biochemical insights into the dicing mechanism of mouse Dicer: A conserved lysine is critical for dsRNA cleavage.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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1DJ9
 | | CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY. | | 分子名称: | 8-AMINO-7-OXONONANOATE SYNTHASE, MAGNESIUM ION, N-[7-KETO-8-AMINOPELARGONIC ACID]-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | | 著者 | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | | 登録日 | 1999-12-02 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
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1DBI
 | | CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE PROTEASE | | 分子名称: | AK.1 SERINE PROTEASE, CALCIUM ION, SODIUM ION | | 著者 | Smith, C.A, Toogood, H.S, Baker, H.M, Daniel, R.M, Baker, E.N. | | 登録日 | 1999-11-02 | | 公開日 | 1999-11-18 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak.1 protease at 1.8 A resolution.
J.Mol.Biol., 294, 1999
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1DJE
 | | CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE | | 分子名称: | 8-AMINO-7-OXONANOATE SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | | 登録日 | 1999-12-02 | | 公開日 | 2000-12-04 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
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1DJ0
 | | THE CRYSTAL STRUCTURE OF E. COLI PSEUDOURIDINE SYNTHASE I AT 1.5 ANGSTROM RESOLUTION | | 分子名称: | CHLORIDE ION, PSEUDOURIDINE SYNTHASE I | | 著者 | Foster, P.G, Huang, L, Santi, D.V, Stroud, R.M. | | 登録日 | 1999-11-30 | | 公開日 | 2000-05-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The structural basis for tRNA recognition and pseudouridine formation by pseudouridine synthase I.
Nat.Struct.Biol., 7, 2000
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1DIY
 | | CRYSTAL STRUCTURE OF ARACHIDONIC ACID BOUND IN THE CYCLOOXYGENASE ACTIVE SITE OF PGHS-1 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ARACHIDONIC ACID, ... | | 著者 | Malkowski, M.G, Ginell, S.L, Smith, W.L, Garavito, R.M. | | 登録日 | 1999-11-30 | | 公開日 | 2000-09-22 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The productive conformation of arachidonic acid bound to prostaglandin synthase.
Science, 289, 2000
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6A4N
 | | HEWL crystals soaked in 2.5M GuHCl for 8 minutes | | 分子名称: | CHLORIDE ION, GLYCEROL, GUANIDINE, ... | | 著者 | Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V. | | 登録日 | 2018-06-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122, 2019
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2ZKJ
 | | Crystal structure of human PDK4-ADP complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHATE ION, ... | | 著者 | Kato, M, Wynn, R.M, Chuang, J.L, Tso, S.-C, Li, J, Chuang, D.T. | | 登録日 | 2008-03-25 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Pyruvate Dehydrogenase Kinase-4 Structures Reveal a Metastable Open Conformation Fostering Robust Core-free Basal Activity
J.Biol.Chem., 283, 2008
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1DVK
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3D3T
 | | Crystal Structure of HIV-1 CRF01_AE in complex with the substrate p1-p6 | | 分子名称: | HIV-1 protease, P1-P6 SUBSTRATE PEPTIDE | | 著者 | Bandaranayake, R.M, Prabu-Jeyabalan, M, Kakizawa, J, Sugiura, W, Schiffer, C.A. | | 登録日 | 2008-05-12 | | 公開日 | 2008-07-08 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6.
J.Virol., 82, 2008
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6A4Q
 | | HEWL crystals soaked in 2.5M GuHCl for 110 minutes | | 分子名称: | CHLORIDE ION, GLYCEROL, GUANIDINE, ... | | 著者 | Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V. | | 登録日 | 2018-06-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122, 2019
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6AL7
 | | Crystal structure HpiC1 F138S | | 分子名称: | 12-epi-hapalindole C/U synthase, CALCIUM ION | | 著者 | Newmister, S.A, Li, S, Garcia-Borras, M, Sanders, J.N, Yang, S, Lowell, A.N, Yu, F, Smith, J.L, Williams, R.M, Houk, K.N, Sherman, D.H. | | 登録日 | 2017-08-07 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.687 Å) | | 主引用文献 | Structural basis of the Cope rearrangement and cyclization in hapalindole biogenesis.
Nat. Chem. Biol., 14, 2018
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1BID
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6A4O
 | | HEWL crystals soaked in 2.5M GuHCl for 20 minutes | | 分子名称: | CHLORIDE ION, GLYCEROL, GUANIDINE, ... | | 著者 | Tushar, R, Kini, R.M, Koh, C.Y, Hosur, M.V. | | 登録日 | 2018-06-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding.
Int. J. Biol. Macromol., 122, 2019
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1DTW
 | | HUMAN BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE | | 分子名称: | BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE ALPHA SUBUNIT, BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE BETA SUBUNIT, MAGNESIUM ION, ... | | 著者 | AEvarsson, A, Chuang, J.L, Wynn, R.M, Turley, S, Chuang, D.T, Hol, W.G.J. | | 登録日 | 2000-01-13 | | 公開日 | 2000-03-27 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of human branched-chain alpha-ketoacid dehydrogenase and the molecular basis of multienzyme complex deficiency in maple syrup urine disease.
Structure Fold.Des., 8, 2000
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3CEP
 | | Structure of a tryptophan synthase quinonoid intermediate | | 分子名称: | 3-hydroxy-2-iminopropanoic acid, CESIUM ION, INDOLINE, ... | | 著者 | Barends, T.R.M, Domratcheva, T, Kulik, V, Blumenstein, L, Dunn, M.F, Schlichting, I. | | 登録日 | 2008-02-29 | | 公開日 | 2008-04-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and mechanistic implications of a tryptophan synthase quinonoid intermediate.
Chembiochem, 9, 2008
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1DZ4
 | | ferric p450cam from pseudomonas putida | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYTOCHROME P450-CAM, ... | | 著者 | Schlichting, I, Berendzen, J, Chu, K, Stock, A.M, Maves, S.A, Benson, D.E, Sweet, R.M, Ringe, D, Petsko, G.A, Sligar, S.G. | | 登録日 | 2000-02-16 | | 公開日 | 2000-07-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The Catalytic Pathway of Cytochrome P450Cam at Atomic Resolution
Science, 287, 2000
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1CI7
 | | TERNARY COMPLEX OF THYMIDYLATE SYNTHASE FROM PNEUMOCYSTIS CARINII | | 分子名称: | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, PROTEIN (THYMIDYLATE SYNTHASE) | | 著者 | Anderson, A.C, O'Neil, R.H, Delano, W.L, Stroud, R.M. | | 登録日 | 1999-04-08 | | 公開日 | 2000-04-10 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structural mechanism for half-the-sites reactivity in an enzyme, thymidylate synthase, involves a relay of changes between subunits.
Biochemistry, 38, 1999
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3CVU
 | | Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion | | 分子名称: | DNA (5'-D(*DAP*DCP*DAP*DGP*DCP*DGP*DGP*(64T)P*(5PY)P*DGP*DCP*DAP*DGP*DGP*DT)-3'), DNA (5'-D(*DTP*DAP*DCP*DCP*DTP*DGP*DCP*DAP*DAP*DCP*DCP*DGP*DCP*DTP*DG)-3'), FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Maul, M.J, Barends, T.R.M, Glas, A.F, Cryle, M.J, Schlichting, I, Carell, T. | | 登録日 | 2008-04-20 | | 公開日 | 2008-11-04 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure and mechanism of a DNA (6-4) photolyase.
Angew.Chem.Int.Ed.Engl., 47, 2008
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