3D3T

Crystal Structure of HIV-1 CRF01_AE in complex with the substrate p1-p6

Summary for 3D3T

• Entry DOI: 10.2210/pdb3d3t/pdb
• Descriptor: HIV-1 protease, P1-P6 SUBSTRATE PEPTIDE (3 entities in total)
• Functional Keywords: hiv-1 protease, non-b clades, crf01_ae, p1-p6 substrate, aids, aspartyl protease, hydrolase
• Biological source: Human immunodeficiency virus 1; More
• Cellular location: Gag polyprotein: Host cell membrane ; Lipid-anchor . Matrix protein p17: Virion membrane ; Lipid-anchor . Capsid protein p24: Virion . Nucleocapsid protein p7: Virion : P12495
• Total number of polymer chains: 3
• Total formula weight: 22786.93

Authors

Bandaranayake, R.M.,Prabu-Jeyabalan, M.,Kakizawa, J.,Sugiura, W.,Schiffer, C.A. (deposition date: 2008-05-12, release date: 2008-07-08, Last modification date: 2024-02-21)

• Primary citation: Bandaranayake, R.M.,Prabu-Jeyabalan, M.,Kakizawa, J.,Sugiura, W.,Schiffer, C.A.; Structural analysis of human immunodeficiency virus type 1 CRF01_AE protease in complex with the substrate p1-p6.; J.Virol., 82:6762-6766, 2008; PubMed: 18434392; DOI: 10.1128/JVI.00018-08

Experimental method

X-RAY DIFFRACTION (2.8 Å)