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PDB: 2928 results

2IFZ
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Lys6 Variant of ImI Conotoxin
Descriptor: Alpha-conotoxin ImI
Authors:Kini, R.M, Kang, T.S.
Deposit date:2006-09-22
Release date:2007-08-14
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins
Biochemistry, 46, 2007
2IHW
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BU of 2ihw by Molmil
Crystal structure of a cubic core of the dihydrolipoamide acyltransferase (E2b) component in the branched-chain alpha-ketoacid dehydrogenase complex (BCKDC), apo form
Descriptor: ACETATE ION, CHLORIDE ION, Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex
Authors:Kato, M, Wynn, R.M, Chuang, J.L, Brautigam, C.A, Custorio, M, Chuang, D.T.
Deposit date:2006-09-27
Release date:2006-12-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A synchronized substrate-gating mechanism revealed by cubic-core structure of the bovine branched-chain alpha-ketoacid dehydrogenase complex.
Embo J., 25, 2006
2IS9
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BU of 2is9 by Molmil
Structure of yeast DCN-1
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Defective in cullin neddylation protein 1, ...
Authors:Yang, X, Zhou, J, Sun, L, Wei, Z, Gao, J, Gong, W, Xu, R.M, Rao, Z, Liu, Y.
Deposit date:2006-10-16
Release date:2007-06-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the function of DCN-1 in protein Neddylation.
J.Biol.Chem., 282, 2007
5IU7
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BU of 5iu7 by Molmil
Crystal structure of stabilized A2A adenosine receptor A2AR-StaR2-bRIL in complex with compound 12c at 1.9A resolution
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-(furan-2-yl)-N~5~-[2-(4-phenylpiperidin-1-yl)ethyl][1,2,4]triazolo[1,5-a][1,3,5]triazine-5,7-diamine, ...
Authors:Segala, E, Guo, D, Cheng, R.K.Y, Bortolato, A, Deflorian, F, Dore, A.S, Errey, J.C, Heitman, L.H, Ijzerman, A.P, Marshall, F.H, Cooke, R.M.
Deposit date:2016-03-17
Release date:2016-06-29
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Controlling the Dissociation of Ligands from the Adenosine A2A Receptor through Modulation of Salt Bridge Strength.
J.Med.Chem., 59, 2016
7SI6
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BU of 7si6 by Molmil
Structure of ATP7B in state 1
Descriptor: MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION
Authors:Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P.
Deposit date:2021-10-12
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3.32 Å)
Cite:Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
7SI7
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BU of 7si7 by Molmil
Structure of ATP7B in state 2
Descriptor: MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION
Authors:Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P.
Deposit date:2021-10-12
Release date:2022-03-16
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
2IH7
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BU of 2ih7 by Molmil
Amidated Pro6 Analogue of CMrVIA conotoxin
Descriptor: Lambda-conotoxin CMrVIA
Authors:Kini, R.M, Kang, T.S.
Deposit date:2006-09-26
Release date:2007-08-14
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Protein folding determinants: structural features determining alternative disulfide pairing in alpha- and chi/lambda-conotoxins
Biochemistry, 46, 2007
7SI3
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BU of 7si3 by Molmil
Consensus structure of ATP7B
Descriptor: MAGNESIUM ION, P-type Cu(+) transporter, TETRAFLUOROALUMINATE ION
Authors:Bitter, R.M, Oh, S.C, Hite, R.K, Yuan, P.
Deposit date:2021-10-12
Release date:2022-03-16
Method:ELECTRON MICROSCOPY (3.19 Å)
Cite:Structure of the Wilson disease copper transporter ATP7B.
Sci Adv, 8, 2022
4DE8
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BU of 4de8 by Molmil
LytR-Cps2a-Psr family protein with bound octaprenyl monophosphate lipid
Descriptor: (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl dihydrogen phosphate, Cps2A, DI(HYDROXYETHYL)ETHER
Authors:Eberhardt, A, Hoyland, C.N, Vollmer, D.V, Bisle, S, Cleverley, R.M, Johnsborg, O, Havarstein, L.S, Lewis, R.J, Vollmer, W.
Deposit date:2012-01-20
Release date:2012-04-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Attachment of Capsular Polysaccharide to the Cell Wall in Streptococcus pneumoniae.
Microb Drug Resist, 18, 2012
2H3K
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BU of 2h3k by Molmil
Solution Structure of the first NEAT domain of IsdH
Descriptor: Haptoglobin-binding surface anchored protein
Authors:Pilpa, R.M, Fadeev, E.A, Villareal, V.A, Wong, M.A, Phillips, M, Clubb, R.T.
Deposit date:2006-05-22
Release date:2006-08-22
Last modified:2024-05-08
Method:SOLUTION NMR
Cite:Solution structure of the NEAT (NEAr Transporter) domain from IsdH/HarA: the human hemoglobin receptor in Staphylococcus aureus.
J.Mol.Biol., 360, 2006
4JG6
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BU of 4jg6 by Molmil
RSK2 CTD bound to 2-cyano-3-(1H-indazol-5-yl)acrylamide
Descriptor: (2S)-2-cyano-3-(1H-indazol-5-yl)propanamide, Ribosomal protein S6 kinase alpha-3, SODIUM ION
Authors:Miller, R.M, Paavilainen, V.O, Krishnan, S, Serafimova, I.M, Taunton, J.
Deposit date:2013-02-28
Release date:2013-04-10
Last modified:2013-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Electrophilic fragment-based design of reversible covalent kinase inhibitors.
J.Am.Chem.Soc., 135, 2013
4TRJ
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BU of 4trj by Molmil
Crystal structure of Mycobacterium tuberculosis enoyl reductase (INHA) complexed with N-(3-bromophenyl)-1-cyclohexyl-5-oxopyrrolidine-3-carboxamide, refined with new ligand restraints
Descriptor: (3S)-N-(3-BROMOPHENYL)-1-CYCLOHEXYL-5-OXOPYRROLIDINE-3-CARBOXAMIDE, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:He, X, Alian, A, Stroud, R.M, Ortiz de Montellano, P.R.
Deposit date:2014-06-17
Release date:2014-08-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
J. Med. Chem., 2006
4IAO
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BU of 4iao by Molmil
Crystal structure of Sir2 C543S mutant in complex with SID domain of Sir4
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent histone deacetylase SIR2, Regulatory protein SIR4, ...
Authors:Hsu, H.C, Wang, C.L, Wang, M, Yang, N, Chen, Z, Sternglanz, R, Xu, R.M.
Deposit date:2012-12-07
Release date:2012-12-26
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.901 Å)
Cite:Structural basis for allosteric stimulation of Sir2 activity by Sir4 binding
Genes Dev., 27, 2013
4F37
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BU of 4f37 by Molmil
Structure of the tethered N-terminus of Alzheimer's disease A peptide
Descriptor: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
Authors:Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
Deposit date:2012-05-09
Release date:2013-05-15
Last modified:2014-09-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
4WUY
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BU of 4wuy by Molmil
Crystal Structure of Protein Lysine Methyltransferase SMYD2 in complex with LLY-507, a Cell-Active, Potent and Selective Inhibitor
Descriptor: 5-cyano-2'-{4-[2-(3-methyl-1H-indol-1-yl)ethyl]piperazin-1-yl}-N-[3-(pyrrolidin-1-yl)propyl]biphenyl-3-carboxamide, GLYCEROL, N-lysine methyltransferase SMYD2, ...
Authors:Nguyen, H, Allali-Hassani, A, Antonysamy, S, Chang, S, Chen, L.H, Curtis, C, Emtage, S, Fan, L, Gheyi, T, Li, F, Liu, S, Martin, J.R, Mendel, D, Olsen, J.B, Pelletier, L, Shatseva, T, Wu, S, Zhang, F.F, Arrowsmith, C.H, Brown, P.J, Campbell, R.M, Garcia, B.A, Barsyte-Lovejoy, D, Mader, M, Vedadi, M.
Deposit date:2014-11-04
Release date:2015-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
J.Biol.Chem., 290, 2015
4JUK
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BU of 4juk by Molmil
Crystal structure of H5N1 influenza virus hemagglutinin, clade 2.3.2.1
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, Hemagglutinin HA2, ...
Authors:DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J.
Deposit date:2013-03-25
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7502 Å)
Cite:To be published
To be Published
4JUN
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BU of 4jun by Molmil
Crystal structure of H5N1 influenza virus hemagglutinin, clade 5
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J.
Deposit date:2013-03-25
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.3398 Å)
Cite:To be published
To be Published
4JUL
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BU of 4jul by Molmil
Crystal structure of H5N1 influenza virus hemagglutinin, clade 2.3.4
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1, ...
Authors:DuBois, R.M, Zaraket, H, Reddivari, M, Coop, T, Heath, R.J, White, S.W, Russell, C.J.
Deposit date:2013-03-25
Release date:2014-05-07
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.7927 Å)
Cite:To be published
To be Published
4FGT
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BU of 4fgt by Molmil
Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.
Descriptor: CG peptide, SULFATE ION, Thymidylate synthase
Authors:Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P.
Deposit date:2012-06-04
Release date:2013-03-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides.
J.Med.Chem., 58, 2015
4J6E
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BU of 4j6e by Molmil
Structure of LPXI D225A Mutant
Descriptor: (2R,3R,4R,5S,6R)-2-{[(S)-{[(S)-{[(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(3R)-3-hydroxytetradecanoyl]amino}tetrahydro-2H-pyran-4-yl (3R)-3-hydroxytetradecanoate, UDP-2,3-diacylglucosamine pyrophosphatase LpxI
Authors:Metzger IV, L.E, Lee, J.K, Finer-Moore, J.S, Raetz, C.R.H, Stroud, R.M, Center for Structures of Membrane Proteins (CSMP)
Deposit date:2013-02-11
Release date:2013-05-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:LpxI structures reveal how a lipid A precursor is synthesized.
Nat.Struct.Mol.Biol., 19, 2012
7TCU
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BU of 7tcu by Molmil
Methanobactin biosynthetic protein complex of MbnB and MbnC from Methylosinus trichosporium OB3b at 2.31 Angstrom resolution
Descriptor: FE (III) ION, Methanobactin biosynthesis cassette protein MbnB, Methanobactin biosynthesis cassette protein MbnC, ...
Authors:Park, Y, Reyes, R.M, Rosenzweig, A.C.
Deposit date:2021-12-28
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A mixed-valent Fe(II)Fe(III) species converts cysteine to an oxazolone/thioamide pair in methanobactin biosynthesis.
Proc.Natl.Acad.Sci.USA, 119, 2022
4ZL7
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BU of 4zl7 by Molmil
Crystal structure of Pseudomonas aeruginosa DsbA E82I: Crystal I
Descriptor: HEXAETHYLENE GLYCOL, Thiol:disulfide interchange protein DsbA
Authors:McMahon, R.M, Martin, J.L.
Deposit date:2015-05-01
Release date:2015-12-09
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.922 Å)
Cite:Sent packing: protein engineering generates a new crystal form of Pseudomonas aeruginosa DsbA1 with increased catalytic surface accessibility.
Acta Crystallogr. D Biol. Crystallogr., 71, 2015
4C0T
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BU of 4c0t by Molmil
Candida albicans PKh Kinase Domain
Descriptor: LIKELY PROTEIN KINASE
Authors:Schulze, J.O, Pastor-Flores, D, Biondi, R.M.
Deposit date:2013-08-07
Release date:2013-10-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:The Pif-Pocket as a Target for C. Albicans Pkh Selective Inhibitors.
Acs Chem.Biol., 8, 2013
5J8H
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BU of 5j8h by Molmil
Structure of calmodulin in a complex with a peptide derived from a calmodulin-dependent kinase
Descriptor: CALCIUM ION, Calmodulin, Eukaryotic elongation factor 2 kinase
Authors:Alphonse, S, Lee, K, Piserchio, A, Tavares, C.D.J, Giles, D.H, Wellmann, R.M, Dalby, K.N, Ghose, R.
Deposit date:2016-04-07
Release date:2016-09-07
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin.
Structure, 24, 2016
4BXW
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BU of 4bxw by Molmil
Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis
Descriptor: COAGULATION FACTOR V, FACTOR XA, GLYCEROL, ...
Authors:Lechtenberg, B.C, Murray-Rust, T.A, Johnson, D.J.D, Adams, T.E, Krishnaswamy, S, Camire, R.M, Huntington, J.A.
Deposit date:2013-07-16
Release date:2013-07-31
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:Crystal Structure of the Prothrombinase Complex from the Venom of Pseudonaja Textilis.
Blood, 122, 2013

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