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PDB: 2930 results

1YM7
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G Protein-Coupled Receptor Kinase 2 (GRK2)
Descriptor: Beta-adrenergic receptor kinase 1
Authors:Lodowski, D.T, Barnhill, J.F, Pyskadlo, R.M, Ghirlando, R, Sterne-Marr, R, Tesmer, J.J.G.
Deposit date:2005-01-20
Release date:2005-07-05
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:The role of Gbetagamma and domain interfaces in the activation of G protein-coupled receptor kinase 2
Biochemistry, 44, 2005
1TCM
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CYCLODEXTRIN GLYCOSYLTRANSFERASE W616A MUTANT FROM BACILLUS CIRCULANS STRAIN 251
Descriptor: CALCIUM ION, CYCLODEXTRIN GLYCOSYLTRANSFERASE
Authors:Knegtel, R.M.A, Dijkstra, B.W.
Deposit date:1996-10-07
Release date:1997-04-21
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The raw starch binding domain of cyclodextrin glycosyltransferase from Bacillus circulans strain 251.
J.Biol.Chem., 271, 1996
1YT0
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Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL SOAKED WITH ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
Authors:Dollins, D.E, Immormino, R.M, Gewirth, D.T.
Deposit date:2005-02-09
Release date:2005-06-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1SYN
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E. COLI THYMIDYLATE SYNTHASE IN COMPLEX WITH BW1843U89 AND 2'-DEOXYURIDINE 5'-MONOPHOSPHATE (DUMP)
Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, S)-2-(5(((1,2-DIHYDRO-3-METHYL-1-OXOBENZO(F)QUINAZOLIN-9-YL)METHYL)AMINO)1-OXO-2-ISOINDOLINYL)GLUTARIC ACID, THYMIDYLATE SYNTHASE
Authors:Stout, T.J, Stroud, R.M.
Deposit date:1995-09-19
Release date:1996-01-29
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2 Å)
Cite:The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.
Structure, 4, 1996
1SU9
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Reduced structure of the soluble domain of ResA
Descriptor: Thiol-disulfide oxidoreductase resA
Authors:Crow, A, Acheson, R.M, Le Brun, N.E, Oubrie, A.
Deposit date:2004-03-26
Release date:2004-05-11
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural Basis of Redox-coupled Protein Substrate Selection by the Cytochrome c Biosynthesis Protein ResA.
J.Biol.Chem., 279, 2004
1YT1
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Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N(DELTA)41 APO CRYSTAL
Descriptor: Endoplasmin, PENTAETHYLENE GLYCOL, TETRAETHYLENE GLYCOL
Authors:Dollins, D.E, Immormino, R.M, Gewirth, D.T.
Deposit date:2005-02-09
Release date:2005-06-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1YLR
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The structure of E.coli nitroreductase with bound acetate, crystal form 1
Descriptor: ACETATE ION, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase
Authors:Race, P.R, Lovering, A.L, Green, R.M, Ossor, A, White, S.A, Searle, P.F, Wrighton, C.J, Hyde, E.I.
Deposit date:2005-01-19
Release date:2005-02-08
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and mechanistic studies of Escherichia coli nitroreductase with the antibiotic nitrofurazone. Reversed binding orientations in different redox states of the enzyme.
J.Biol.Chem., 280, 2005
4EHR
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Crystal structure of Bcl-Xl complex with 4-(5-butyl-3-(hydroxymethyl)-1-phenyl-1h-pyrazol-4-yl)-3-(3,4-dihydro-2(1h)-isoquinolinylcarbonyl)-n-((2-(trimethylsilyl)ethyl)sulfonyl)benzamide
Descriptor: 4-[5-butyl-3-(hydroxymethyl)-1-phenyl-1H-pyrazol-4-yl]-3-(3,4-dihydroisoquinolin-2(1H)-ylcarbonyl)-N-{[2-(trimethylsilyl)ethyl]sulfonyl}benzamide, Bcl-2-like protein 1, IMIDAZOLE
Authors:Schroeder, G.M, Wei, D, Banfi, P, Cai, Z, Lippy, J, Menichincheri, M, Modugno, M, Naglich, J, Penhallow, B, Perez, H.L, Sack, J, Schmidt, R.J, Tebben, A, Yan, C, Zhang, L, Galvani, A, Lombardo, L.J, Borzilleri, R.M.
Deposit date:2012-04-03
Release date:2012-06-06
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Pyrazole and pyrimidine phenylacylsulfonamides as dual Bcl-2/Bcl-xL antagonists.
Bioorg.Med.Chem.Lett., 22, 2012
1YNY
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Molecular Structure of D-Hydantoinase from a Bacillus sp. AR9: Evidence for mercury inhibition
Descriptor: D-Hydantoinase, MANGANESE (II) ION
Authors:Radha Kishan, K.V, Vohra, R.M, Ganeshan, K, Agrawal, V, Sharma, V.M, Sharma, R.
Deposit date:2005-01-26
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular structure of D-hydantoinase from Bacillus sp. AR9: evidence for mercury inhibition.
J.Mol.Biol., 347, 2005
1YT2
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Crystal Structure of the Unliganded Form of GRP94, the ER Hsp90: Basis for Nucleotide-Induced Conformational Change, GRP94N APO CRYSTAL
Descriptor: Endoplasmin, TETRAETHYLENE GLYCOL
Authors:Dollins, D.E, Immormino, R.M, Gewirth, D.T.
Deposit date:2005-02-09
Release date:2005-06-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structure of Unliganded GRP94, the Endoplasmic Reticulum Hsp90: BASIS FOR NUCLEOTIDE-INDUCED CONFORMATIONAL CHANGE
J.Biol.Chem., 280, 2005
1ZO8
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X-ray Structure of the haloalcohol dehalogenase HheC of Agrobacterium radiobacter AD1 in complex with (S)-para-nitrostyrene oxide, with a water molecule in the halide-binding site
Descriptor: (S)-PARA-NITROSTYRENE OXIDE, halohydrin dehalogenase
Authors:de Jong, R.M, Tiesinga, J.J.W, Tang, L, Villa, A, Janssen, D.B, Dijkstra, B.W.
Deposit date:2005-05-12
Release date:2005-10-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for the Enantioselectivity of an Epoxide Ring Opening Reaction Catalyzed by Halo Alcohol Dehalogenase HheC.
J.Am.Chem.Soc., 127, 2005
1YYT
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D100E Trichodiene Synthase: Complex With Mg, Pyrophosphate, and (4R)-7-azabisabolene
Descriptor: (1S)-N,4-DIMETHYL-N-(4-METHYLPENT-3-ENYL)CYCLOHEX-3-ENAMINIUM, MAGNESIUM ION, PYROPHOSPHATE 2-, ...
Authors:Vedula, L.S, Rynkiewicz, M.J, Pyun, H.J, Coates, R.M, Cane, D.E, Christianson, D.W.
Deposit date:2005-02-25
Release date:2005-03-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants.
Biochemistry, 44, 2005
1TBW
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Ligand Induced Conformational Shift in the N-terminal Domain of GRP94, Open Conformation
Descriptor: ADENOSINE MONOPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
Authors:Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
Deposit date:2004-05-20
Release date:2004-08-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
1YYR
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Y305F Trichodiene Synthase: Complex With Mg, Pyrophosphate, and (4R)-7-azabisabolene
Descriptor: (1S)-N,4-DIMETHYL-N-(4-METHYLPENT-3-ENYL)CYCLOHEX-3-ENAMINIUM, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Vedula, L.S, Rynkiewicz, M.J, Pyun, H.J, Coates, R.M, Cane, D.E, Christianson, D.W.
Deposit date:2005-02-25
Release date:2005-03-29
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants.
Biochemistry, 44, 2005
1TDB
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BU of 1tdb by Molmil
STRUCTURES OF THYMIDYLATE SYNTHASE WITH A C-TERMINAL DELETION: ROLE OF THE C-TERMINUS IN ALIGNMENT OF D/UMP AND CH2H4FOLATE
Descriptor: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, THYMIDYLATE SYNTHASE
Authors:Perry, K.M, Carreras, C.W, Chang, L.C, Santi, D.V, Stroud, R.M.
Deposit date:1993-02-15
Release date:1993-07-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structures of thymidylate synthase with a C-terminal deletion: role of the C-terminus in alignment of 2'-deoxyuridine 5'-monophosphate and 5,10-methylenetetrahydrofolate.
Biochemistry, 32, 1993
1TC0
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Ligand Induced Conformational Shifts in the N-terminal Domain of GRP94, Open Conformation Complexed with the physiological partner ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Endoplasmin, MAGNESIUM ION, ...
Authors:Gewirth, D.T, Immormino, R.M, Dollins, D.E, Shaffer, P.L, Walker, M.A, Soldano, K.L.
Deposit date:2004-05-20
Release date:2004-08-24
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.
J.Biol.Chem., 279, 2004
2LC9
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Solution Structure of a Minor and Transiently Formed State of a T4 Lysozyme Mutant
Descriptor: Lysozyme
Authors:Bouvignies, G, Vallurupalli, P, Hansen, D, Correia, B, Lange, O, Bah, A, Vernon, R.M, Dahlquist, F.W, Baker, D, Kay, L.E.
Deposit date:2011-04-26
Release date:2011-08-17
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of a minor and transiently formed state of a T4 lysozyme mutant.
Nature, 477, 2011
1TF6
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CO-CRYSTAL STRUCTURE OF XENOPUS TFIIIA ZINC FINGER DOMAIN BOUND TO THE 5S RIBOSOMAL RNA GENE INTERNAL CONTROL REGION
Descriptor: DNA (5'-D(*AP*CP*GP*GP*GP*CP*CP*TP*GP*GP*TP*TP*AP*GP*TP*AP*C P*CP*TP*GP*GP*AP* TP*GP*GP*GP*AP*GP*AP*CP*C)-3'), DNA (5'-D(*TP*GP*GP*TP*CP*TP*CP*CP*CP*AP*TP*CP*CP*AP*GP*GP*T P*AP*CP*TP*AP*AP* CP*CP*AP*GP*GP*CP*CP*CP*G)-3'), PROTEIN (TRANSCRIPTION FACTOR IIIA), ...
Authors:Nolte, R.T, Conlin, R.M, Harrison, S.C, Brown, R.S.
Deposit date:1998-03-02
Release date:1998-07-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Differing roles for zinc fingers in DNA recognition: structure of a six-finger transcription factor IIIA complex.
Proc.Natl.Acad.Sci.USA, 95, 1998
1TGN
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STRUCTURE OF BOVINE TRYPSINOGEN AT 1.9 ANGSTROMS RESOLUTION
Descriptor: TRYPSINOGEN
Authors:Kossiakoff, A.A, Stroud, R.M.
Deposit date:1979-09-19
Release date:1979-10-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structure of bovine trypsinogen at 1.9 A resolution.
Biochemistry, 16, 1977
2LJB
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Structure of the influenza AM2-BM2 chimeric channel
Descriptor: M2 protein, BM2 protein chimera
Authors:Pielak, R.M, Oxenoid, K, Chou, J.J.
Deposit date:2011-09-10
Release date:2011-11-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural investigation of rimantadine inhibition of the AM2-BM2 chimera channel of influenza viruses.
Structure, 19, 2011
1ZW9
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Yeast HSP82 in complex with the Novel HSP90 Inhibitor 8-(6-Bromo-benzo[1,3]dioxol-5-ylsulfanyl)-9-(3-isopropylamino-propyl)-adenine
Descriptor: 8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE, HSP82
Authors:Immormino, R.M, Gewirth, D.T, Chiosis, G.
Deposit date:2005-06-03
Release date:2006-06-13
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Inhibitory Ligands Adopt Different Conformations When Bound to Hsp90 or GRP94: Implications for Paralog-specific Drug Design
To be Published
4FVQ
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Crystal structure of the Jak2 pseudokinase domain (Mg-ATP-bound form)
Descriptor: ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Bandaranayake, R.M, Hubbard, S.R.
Deposit date:2012-06-29
Release date:2012-07-25
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F.
Nat.Struct.Mol.Biol., 19, 2012
2AE9
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Solution Structure of the theta subunit of DNA polymerase III from E. coli
Descriptor: DNA polymerase III, theta subunit
Authors:Mueller, G.A, Kirby, T.W, Derose, E.F, Li, D, Schaaper, R.M, London, R.E.
Deposit date:2005-07-21
Release date:2005-10-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Nuclear Magnetic Resonance Solution Structure of the Escherichia coli DNA Polymerase III {theta} Subunit.
J.Bacteriol., 187, 2005
1T61
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crystal structure of collagen IV NC1 domain from placenta basement membrane
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Vanacore, R.M, Shanmugasundararaj, S, Friedman, D.B, Bondar, O, Hudson, B.G, Sundaramoorthy, M.
Deposit date:2004-05-05
Release date:2004-09-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The alpha1.alpha2 network of collagen IV. Reinforced stabilization of the noncollagenous domain-1 by noncovalent forces and the absence of Met-Lys cross-links
J.Biol.Chem., 279, 2004
8D9V
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gamma-Arf1 homodimeric interface within AP-1, Arf1, Nef lattice on narrow membrane tubes
Descriptor: ADP ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
Authors:Hooy, R.M, Hurley, J.H.
Deposit date:2022-06-11
Release date:2022-11-09
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Self-assembly and structure of a clathrin-independent AP-1:Arf1 tubular membrane coat.
Sci Adv, 8, 2022

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