1TC0

Ligand Induced Conformational Shifts in the N-terminal Domain of GRP94, Open Conformation Complexed with the physiological partner ATP

Summary for 1TC0

• Entry DOI: 10.2210/pdb1tc0/pdb
• Related: 1QY5 1QY8 1QYE 1QYH 1TBW 1TC6
• Descriptor: Endoplasmin, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: grp94, hsp90, atp, bergerat, chaperone, endoplasmic reticulum
• Biological source: Canis lupus familiaris (dog); More
• Cellular location: Endoplasmic reticulum lumen: P41148
• Total number of polymer chains: 2
• Total formula weight: 55062.13

Authors

Gewirth, D.T.,Immormino, R.M.,Dollins, D.E.,Shaffer, P.L.,Walker, M.A.,Soldano, K.L. (deposition date: 2004-05-20, release date: 2004-08-24, Last modification date: 2024-02-14)

• Primary citation: Immormino, R.M.,Dollins, D.E.,Shaffer, P.L.,Soldano, K.L.,Walker, M.A.,Gewirth, D.T.; Ligand-induced Conformational Shift in the N-terminal Domain of GRP94, an Hsp90 Chaperone.; J.Biol.Chem., 279:46162-46171, 2004; PubMed: 15292259; DOI: 10.1074/jbc.M405253200

Experimental method

X-RAY DIFFRACTION (2.2 Å)