1TC0

Ligand Induced Conformational Shifts in the N-terminal Domain of GRP94, Open Conformation Complexed with the physiological partner ATP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Endoplasmin	polymer	236	26514.0	2	UniProt (P41148) Pfam (PF13589) In PDB	Canis lupus familiaris (dog)	94 kDa glucose-regulated protein, GRP94
2	A, B	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
3	A, B	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
4	A, B	TETRAETHYLENE GLYCOL	non-polymer		194.2	5	Chemie (PG4)
5		water	water		18.0	203	Chemie (HOH)

Sequence modifications

A, B: 69 - 286 (UniProt: P41148)

PDB	External Database	Details
Gly 65	-	cloning artifact
Ser 66	-	cloning artifact
His 67	-	cloning artifact
Met 68	-	cloning artifact

A, B: 328 - 337 (UniProt: P41148)

PDB	External Database	Details
Gly 287	-	SEE REMARK 999
Gly 288	-	SEE REMARK 999
Gly 289	-	SEE REMARK 999
Gly 290	-	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53028.0
Non-Polymers*	Number of molecules	9
	Total formula weight	2034.1
All*	Total formula weight	55062.1

*Water molecules are not included.