2XKJ
 
 | | CRYSTAL STRUCTURE OF CATALYTIC CORE OF A. BAUMANNII TOPO IV (PARE- PARC FUSION TRUNCATE) | | 分子名称: | GLYCEROL, SULFATE ION, TOPOISOMERASE IV | | 著者 | Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D. | | 登録日 | 2010-07-08 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
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2XKK
 | | CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE) | | 分子名称: | 1-cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA, MAGNESIUM ION, ... | | 著者 | Wohlkonig, A, Chan, P.F, Fosberry, A.P, Homes, P, Huang, J, Kranz, M, Leydon, V.R, Miles, T.J, Pearson, N.D, Perera, R.L, Shillings, A.J, Gwynn, M.N, Bax, B.D. | | 登録日 | 2010-07-08 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance
Nat.Struct.Mol.Biol., 17, 2010
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1D1P
 | | CRYSTAL STRUCTURE OF A YEAST LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE (LTP1) | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TYROSINE PHOSPHATASE | | 著者 | Wang, S, Tabernero, L, Zhang, M, Harms, E, Van Etten, R.L, Stauffacher, C.V. | | 登録日 | 1999-09-20 | | 公開日 | 2000-03-08 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Biochemistry, 39, 2000
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1GGI
 | | CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN | | 分子名称: | HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN) | | 著者 | Stanfield, R.L, Rini, J.M, Wilson, I.A. | | 登録日 | 1993-04-02 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proc.Natl.Acad.Sci.USA, 90, 1993
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1DJY
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2,4,5-TRISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-2,4,5-TRIPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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2XCN
 | | Crystal structure of HCV NS3 protease with a boronate inhibitor | | 分子名称: | MAGNESIUM ION, N-[(CYCLOPENTYLOXY)CARBONYL]-3-METHYL-L-VALYL-(4R)-N-{(1R)-3-HYDROXY-1-[HYDROXY(OXIDO)BORANYL]PROPYL}-4-(ISOQUINOLIN-1-YLOXY)-L-PROLINAMIDE, NS3 PROTEASE, ... | | 著者 | Li, X, Zhang, Y.-K, Liu, Y, Ding, C.Z, Li, Q, Zhou, Y, Plattner, J.J, Baker, S.J, Qian, X, Fan, D, Liao, L, Ni, Z.-J, White, G.V, Mordaunt, J.E, Lazarides, L.X, Slater, M.J, Jarvest, R.L, Thommes, P, Ellis, M, Edge, C.M, Hubbard, J.A, Nassau, P, McDowell, B, Skarzynski, T.J, Rowland, P, Somers, D.O, Kazmierski, W.M, Grimes, R.M, Wright, L.L, Smith, G.K, Zou, W, Wright, J, Pennicott, L.E. | | 登録日 | 2010-04-23 | | 公開日 | 2010-06-02 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.02 Å) | | 主引用文献 | Synthesis and Evaluation of Novel Alpha-Amino Cyclic Boronates as Inhibitors of Hcv Ns3 Protease.
Bioorg.Med.Chem.Lett., 20, 2010
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1P0Y
 | | Crystal structure of the SET domain of LSMT bound to MeLysine and AdoHcy | | 分子名称: | N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, ... | | 著者 | Trievel, R.C, Flynn, E.M, Houtz, R.L, Hurley, J.H. | | 登録日 | 2003-04-11 | | 公開日 | 2003-07-01 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT
Nat.Struct.Biol., 10, 2003
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4D0M
 | | Phosphatidylinositol 4-kinase III beta in a complex with Rab11a-GTP- gamma-S and the Rab-binding domain of FIP3 | | 分子名称: | 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE, ... | | 著者 | Burke, J.E, Inglis, A.J, Perisic, O, Masson, G.R, McLaughlin, S.H, Rutaganira, F, Shokat, K.M, Williams, R.L. | | 登録日 | 2014-04-29 | | 公開日 | 2014-05-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Structures of Pi4Kiiibeta Complexes Show Simultaneous Recruitment of Rab11 and its Effectors.
Science, 344, 2014
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1SFI
 | | High resolution structure of a potent, cyclic protease inhibitor from sunflower seeds | | 分子名称: | CALCIUM ION, SULFATE ION, TRYPSIN, ... | | 著者 | Luckett, S, Garcia, R.S, Barker, J.J, Konarev, A.V, Shewry, P, Clarke, A.R, Brady, R.L. | | 登録日 | 1998-12-16 | | 公開日 | 1999-07-09 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | High-resolution structure of a potent, cyclic proteinase inhibitor from sunflower seeds.
J.Mol.Biol., 290, 1999
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1SQ2
 | | Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ... | | 著者 | Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A. | | 登録日 | 2004-03-17 | | 公開日 | 2004-08-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science, 305, 2004
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1DJZ
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-4,5-BISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-4,5-BISPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1E7V
 | | Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine | | 分子名称: | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE, PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT | | 著者 | Walker, E.H, Pacold, M.E, Perisic, O, Stephens, L, Hawkins, P.T, Wymann, M.P, Williams, R.L. | | 登録日 | 2000-09-08 | | 公開日 | 2000-11-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine.
Mol.Cell, 6, 2000
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2ZNW
 | | Crystal Structure of ScFv10 in Complex with Hen Egg Lysozyme | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lysozyme C, ScFv10 | | 著者 | DeSantis, M.E, Acchione, M, Li, M, Walter, R.L, Wlodawer, A, Smith-Gill, S. | | 登録日 | 2008-05-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics
Biochemistry, 51, 2012
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4CB8
 | | Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha | | 分子名称: | BETA-CATENIN-LIKE PROTEIN 1, SULFATE ION | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Mutational Analysis Reveals that Ctnnbl1 Binds Nlss in a Manner Distinct from that of its Closest Armadillo-Relative, Karyopherin Alpha
FEBS Lett., 588, 2014
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1IF0
 | | PSEUDO-ATOMIC MODEL OF BACTERIOPHAGE HK97 PROCAPSID (PROHEAD II) | | 分子名称: | PROTEIN (MAJOR CAPSID PROTEIN GP5) | | 著者 | Conway, J.F, Wikoff, W.R, Cheng, N, Duda, R.L, Hendrix, R.W, Johnson, J.E, Steven, A.C. | | 登録日 | 2001-04-11 | | 公開日 | 2001-05-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Virus maturation involving large subunit rotations and local refolding.
Science, 292, 2001
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2ZNX
 | | 5-Fluorotryptophan Incorporated ScFv10 Complexed to Hen Egg Lysozyme | | 分子名称: | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, Lysozyme C, ScFv | | 著者 | DeSantis, M.E, Acchione, M, Li, M, Walter, R.L, Wlodawer, A, Smith-Gill, S. | | 登録日 | 2008-05-02 | | 公開日 | 2009-01-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Specific fluorine labeling of the HyHEL10 antibody affects antigen binding and dynamics
Biochemistry, 51, 2012
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4CPG
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4DZN
 | | A de novo designed Coiled Coil CC-pIL | | 分子名称: | COILED-COIL PEPTIDE CC-PIL | | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | | 登録日 | 2012-03-01 | | 公開日 | 2012-08-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology.
ACS Synth Biol, 1, 2012
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1DJW
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHONATE | | 分子名称: | ACETATE ION, CALCIUM ION, INOSITOL-2-METHYLENE-1,2-CYCLIC-MONOPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-23 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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1DJ9
 | | CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY. | | 分子名称: | 8-AMINO-7-OXONONANOATE SYNTHASE, MAGNESIUM ION, N-[7-KETO-8-AMINOPELARGONIC ACID]-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | | 著者 | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | | 登録日 | 1999-12-02 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
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1DJX
 | | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C-DELTA1 FROM RAT COMPLEXED WITH INOSITOL-1,4,5-TRISPHOSPHATE | | 分子名称: | ACETATE ION, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ... | | 著者 | Essen, L.-O, Perisic, O, Williams, R.L. | | 登録日 | 1996-08-24 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural mapping of the catalytic mechanism for a mammalian phosphoinositide-specific phospholipase C.
Biochemistry, 36, 1997
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4DZM
 | | A de novo designed Coiled Coil CC-Di | | 分子名称: | COILED-COIL PEPTIDE CC-DI | | 著者 | Bruning, M, Thomson, A.R, Zaccai, N.R, Brady, R.L, Woolfson, D.N. | | 登録日 | 2012-03-01 | | 公開日 | 2012-08-29 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | A basis set of de novo coiled-coil Peptide oligomers for rational protein design and synthetic biology.
ACS Synth Biol, 1, 2012
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1RCY
 | | RUSTICYANIN (RC) FROM THIOBACILLUS FERROOXIDANS | | 分子名称: | COPPER (II) ION, RUSTICYANIN | | 著者 | Walter, R.L, Friedman, A.M, Ealick, S.E, Blake II, R.C, Proctor, P, Shoham, M. | | 登録日 | 1996-04-10 | | 公開日 | 1997-05-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Multiple wavelength anomalous diffraction (MAD) crystal structure of rusticyanin: a highly oxidizing cupredoxin with extreme acid stability.
J.Mol.Biol., 263, 1996
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1RBB
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1PG1
 | | PROTEGRIN 1 (PG1) FROM PORCINE LEUKOCYTES, NMR, 20 STRUCTURES | | 分子名称: | PROTEGRIN-1 | | 著者 | Fahrner, R.L, Dieckmann, T, Harwig, S.S.L, Lehrer, R.I, Eisenberg, D, Feigon, J. | | 登録日 | 1998-03-20 | | 公開日 | 1998-05-27 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of protegrin-1, a broad-spectrum antimicrobial peptide from porcine leukocytes.
Chem.Biol., 3, 1996
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