7YX8
 
 | | Crystal structure of the AM0627 (E326A) inactive mutant in complex with PSGL-1-like bis-T glycopeptide and Zn2+ | | 分子名称: | GLYCEROL, PSGL-1-like bis-T glycopeptide, Peptidase M60 domain-containing protein, ... | | 著者 | Taleb, V, Liao, Q, Narimatsu, Y, Garcia-Garcia, A, Companon, I, Borges, R.J, Gonzalez-Ramirez, A.M, Corzana, F, Clausen, H, Rovira, C, Hurtado-Guerrero, R. | | 登録日 | 2022-02-15 | | 公開日 | 2022-07-20 | | 最終更新日 | 2022-08-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural and mechanistic insights into the cleavage of clustered O-glycan patches-containing glycoproteins by mucinases of the human gut.
Nat Commun, 13, 2022
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2RIW
 | | The Reactive loop cleaved human Thyroxine Binding Globulin complexed with thyroxine | | 分子名称: | 3,5,3',5'-TETRAIODO-L-THYRONINE, Thyroxine-binding globulin | | 著者 | Zhou, A, Wei, Z, Stanley, P.L.D, Read, R.J, Stein, P.E, Carrell, R.W. | | 登録日 | 2007-10-12 | | 公開日 | 2008-10-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins
J.Biol.Chem., 286, 2011
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2RL0
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2RO5
 | | RDC-refined solution structure of the N-terminal DNA recognition domain of the Bacillus subtilis transition-state regulator SpoVT | | 分子名称: | Stage V sporulation protein T | | 著者 | Sullivan, D.M, Bobay, B.G, Kojetin, D.J, Thompson, R.J, Rance, M, Strauch, M.A, Cavanagh, J. | | 登録日 | 2008-03-08 | | 公開日 | 2008-11-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Insights into the nature of DNA binding of AbrB-like transcription factors
Structure, 16, 2008
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333D
 | | THE CRYSTAL STRUCTURE OF AN RNA OLIGOMER INCORPORATING TANDEM ADENOSINE-INOSINE MISMATCHES | | 分子名称: | CALCIUM ION, RNA (5'-R(*CP*GP*CP*AP*IP*GP*CP*G)-3') | | 著者 | Carter, R.J, Baeyens, K.J, SantaLucia Jr, J, Turner, D.H, Holbrook, S.R. | | 登録日 | 1997-05-20 | | 公開日 | 1997-10-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | | 主引用文献 | The crystal structure of an RNA oligomer incorporating tandem adenosine-inosine mismatches.
Nucleic Acids Res., 25, 1997
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2RKY
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2V07
 | | Structure of the Arabidopsis thaliana cytochrome c6A V52Q variant | | 分子名称: | CYTOCHROME C6, HEME C | | 著者 | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | | 登録日 | 2007-05-09 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
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2UZ6
 | | AChBP-targeted a-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-CONOTOXIN TXIA(A10L), GLYCEROL, ... | | 著者 | Ulens, C, Dutertre, S, Buttner, R, Fish, A, van Elk, R, Kendel, Y, Hopping, G, Alewood, P.F, Schroeder, C, Nicke, A, Smit, A.B, Sixma, T.K, Lewis, R.J. | | 登録日 | 2007-04-25 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Achbp-Targeted Alpha-Conotoxin Correlates Distinct Binding Orientations with Nachr Subtype Selectivity
Embo J., 26, 2007
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2V5P
 | | COMPLEX STRUCTURE OF HUMAN IGF2R DOMAINS 11-13 BOUND TO IGF-II | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, INSULIN-LIKE GROWTH FACTOR II, ... | | 著者 | Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y. | | 登録日 | 2007-07-06 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | | 主引用文献 | Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
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2VAD
 | | Monomeric red fluorescent protein, DsRed.M1 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, RED FLUORESCENT PROTEIN, ... | | 著者 | Strongin, D.E, Bevis, B, Khuong, N, Downing, M.E, Strack, R.L, Sundaram, K, Glick, B.S, Keenan, R.J. | | 登録日 | 2007-08-30 | | 公開日 | 2007-11-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structural Rearrangements Near the Chromophore Influence the Maturation Speed and Brightness of Dsred Variants.
Protein Eng.Des.Sel., 20, 2007
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2V69
 | | Crystal structure of Chlamydomonas reinhardtii Rubisco with a large- subunit mutation D473E | | 分子名称: | 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Karkehabadi, S, Satagopan, S, Taylor, T.C, Spreitzer, R.J, Andersson, I. | | 登録日 | 2007-07-14 | | 公開日 | 2007-07-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Analysis of Altered Large-Subunit Loop-6-Carboxy-Terminus Interactions that Influence Catalytic Efficiency and Co2-O2 Specificity of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase
Biochemistry, 46, 2007
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2V63
 | | Crystal structure of Rubisco from Chlamydomonas reinhardtii with a large-subunit V331A mutation | | 分子名称: | 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Karkehabadi, S, Satagopagan, S, Taylor, T.C, Spreitzer, R.J, Andersson, I. | | 登録日 | 2007-07-13 | | 公開日 | 2007-07-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Analysis of Altered Large-Subunit Loop-6-Carboxy-Terminus Interactions that Influence Catalytic Efficiency and Co2 O2 Specificity of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase
Biochemistry, 46, 2007
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2VD9
 | | The crystal structure of alanine racemase from Bacillus anthracis (BA0252) with bound L-Ala-P | | 分子名称: | (1S)-1-[((1E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLENE)AMINO]ETHYLPHOSPHONIC ACID, ALANINE RACEMASE, CHLORIDE ION, ... | | 著者 | Au, K, Ren, J, Walter, T.S, Harlos, K, Nettleship, J.E, Owens, R.J, Stuart, D.I, Esnouf, R.M, Oxford Protein Production Facility (OPPF), Structural Proteomics in Europe (SPINE) | | 登録日 | 2007-10-01 | | 公開日 | 2008-05-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of an Alanine Racemase from Bacillus Anthracis (Ba0252) in the Presence and Absence of (R)-1-Aminoethylphosphonic Acid (L-Ala-P).
Acta Crystallogr.,Sect.F, 64, 2008
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2VDY
 | | Crystal structure of the reactive loop cleaved Corticosteroid Binding Globulin complexed with Cortisol | | 分子名称: | (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN | | 著者 | Zhou, A, Wei, Z, Read, R.J. | | 登録日 | 2007-10-13 | | 公開日 | 2008-05-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The S-to-R Transition of Corticosteroid-Binding Globulin and the Mechanism of Hormone Release.
J.Mol.Biol., 380, 2008
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2V68
 | | Crystal structure of Chlamydomonas reinhardtii Rubisco with large- subunit mutations V331A, T342I | | 分子名称: | 1,2-ETHANEDIOL, 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Karkehabadi, S, Satagopan, S, Taylor, T.C, Spreitzer, R.J, Andersson, I. | | 登録日 | 2007-07-13 | | 公開日 | 2007-08-07 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Analysis of Altered Large-Subunit Loop-6-Carboxy-Terminus Interactions that Influence Catalytic Efficiency and Co2 O2 Specificity of Ribulose-1,5-Bisphosphate Carboxylase Oxygenase
Biochemistry, 46, 2007
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2V08
 | | Structure of wild-type Phormidium laminosum cytochrome c6 | | 分子名称: | CHLORIDE ION, CYTOCHROME C6, HEME C, ... | | 著者 | Worrall, J.A.R, Schlarb-Ridley, B.G, Reda, T, Marcaida, M.J, Moorlen, R.J, Wastl, J, Hirst, J, Bendall, D.S, Luisi, B.F, Howe, C.J. | | 登録日 | 2007-05-10 | | 公開日 | 2007-07-24 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Modulation of heme redox potential in the cytochrome c6 family.
J. Am. Chem. Soc., 129, 2007
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2UWP
 | | Factor Xa inhibitor complex | | 分子名称: | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHANESULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X, ... | | 著者 | Young, R.J, Brown, D, Burns-Kurtis, C.L, Chan, C, Convery, M.A, Hubbard, J.A, Kelly, H.A, Pateman, A.J, Patikis, A, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Zhou, P, Thorpe, J.H. | | 登録日 | 2007-03-22 | | 公開日 | 2007-05-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Selective and Dual Action Orally Active Inhibitors of Thrombin and Factor Xa.
Bioorg.Med.Chem.Lett., 17, 2007
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2VWK
 | | Uracil Recognition in Archaeal DNA Polymerases Captured by X-ray Crystallography. V93Q polymerase variant | | 分子名称: | DNA POLYMERASE, SODIUM ION, SULFATE ION | | 著者 | Firbank, S.J, Wardle, J, Heslop, P, Lewis, R.J, Connolly, B.A. | | 登録日 | 2008-06-26 | | 公開日 | 2008-07-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Uracil Recognition in Archaeal DNA Polymerases Captured by X-Ray Crystallography.
J.Mol.Biol., 381, 2008
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2W07
 | | Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF | | 分子名称: | CHAPERONE PROTEIN PAPD, MINOR PILIN SUBUNIT PAPF, SULFATE ION | | 著者 | Verger, D, Rose, R.J, Paci, E, Costakes, G, Daviter, T, Hultgren, S, Remaut, H, Ashcroft, A.E, Radford, S.E, Waksman, G. | | 登録日 | 2008-08-12 | | 公開日 | 2008-11-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structural Determinants of Polymerization Reactivity of the P Pilus Adaptor Subunit Papf.
Structure, 16, 2008
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2VY9
 | | Molecular architecture of the stressosome, a signal integration and transduction hub | | 分子名称: | ANTI-SIGMA-FACTOR ANTAGONIST | | 著者 | Marles-Wright, J, Grant, T, Delumeau, O, van Duinen, G, Firbank, S.J, Lewis, P.J, Murray, J.W, Newman, J.A, Quin, M.B, Race, P.R, Rohou, A, Tichelaar, W, van Heel, M, Lewis, R.J. | | 登録日 | 2008-07-21 | | 公開日 | 2008-10-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular Architecture of the "Stressosome," a Signal Integration and Transduction Hub
Science, 322, 2008
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7ZV2
 | | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | | 登録日 | 2022-05-13 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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7ZVL
 | | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, GLYCEROL, ... | | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | | 登録日 | 2022-05-16 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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7ZUU
 | | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | | 登録日 | 2022-05-13 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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7ZUQ
 | | HUMAN PRMT5:MEP50 Crystal Structure With MTA and Fragment Bound | | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, Methylosome protein 50, ... | | 著者 | Ahmad, M.U, Koelmel, W, Arkhipova, V, Lawson, J.D, Smith, C.R, Gunn, R.J. | | 登録日 | 2022-05-13 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Fragment optimization and elaboration strategies - the discovery of two lead series of PRMT5/MTA inhibitors from five fragment hits.
Rsc Med Chem, 13, 2022
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2VPT
 | | Clostridium thermocellum family 3 carbohydrate esterase | | 分子名称: | CALCIUM ION, LIPOLYTIC ENZYME | | 著者 | Correia, M.A.S, Prates, J.A.M, Bras, J, Fontes, C.M.G.A, Newman, J.A, Lewis, R.J, Gilbert, H.J, Flint, J.E. | | 登録日 | 2008-03-04 | | 公開日 | 2008-05-06 | | 最終更新日 | 2012-01-18 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal Structure of a Cellulosomal Family 3 Carbohydrate Esterase from Clostridium Thermocellum Provides Insights Into the Mechanism of Substrate Recognition
J.Mol.Biol., 379, 2008
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