1MLB
 
 | | MONOCLONAL ANTIBODY FAB D44.1 RAISED AGAINST CHICKEN EGG-WHITE LYSOZYME | | 分子名称: | IGG1-KAPPA D44.1 FAB (HEAVY CHAIN), IGG1-KAPPA D44.1 FAB (LIGHT CHAIN) | | 著者 | Braden, B.C, Souchon, H, Eisele, J.-L, Bentley, G.A, Bhat, T.N, Navaza, J, Poljak, R.J. | | 登録日 | 1995-03-08 | | 公開日 | 1995-06-03 | | 最終更新日 | 2013-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1.
J.Mol.Biol., 243, 1994
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5MN2
 | | Cocrystal structure of Fc gamma receptor IIIa interacting with Affimer G3, a specific binding protein which blocks IgG binding to the receptor. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer G3, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Robinson, J.I, Owen, R.L, Tomlinson, D.C, Baxter, E.W, Nettleship, J.E, Waterhouse, M.P, Harris, S.A, Owens, R.J, McPherson, M.J, Morgan, A.W, Tiede, C, Goldman, A, Thomsen, M. | | 登録日 | 2016-12-12 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Affimer proteins inhibit immune complex binding to Fc gamma RIIIa with high specificity through competitive and allosteric modes of action.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7R6R
 | | Crystal Structure of a Mycobacteriophage Cluster A2 Immunity Repressor:DNA Complex | | 分子名称: | DNA (5'-D(P*CP*CP*CP*GP*CP*TP*TP*GP*AP*CP*AP*GP*CP*CP*AP*CP*CP*GP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*CP*GP*GP*TP*GP*GP*CP*TP*GP*TP*CP*AP*AP*GP*CP*GP*GP*G)-3'), Immunity repressor | | 著者 | McGinnis, R.J, Brambley, C.A, Stamey, B, Green, W.C, Gragg, K.N, Cafferty, E.R, Terwilliger, T.C, Hammel, M, Hollis, T.J, Miller, J.M, Gainey, M.D, Wallen, J.R. | | 登録日 | 2021-06-23 | | 公開日 | 2022-07-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | A monomeric mycobacteriophage immunity repressor utilizes two domains to recognize an asymmetric DNA sequence.
Nat Commun, 13, 2022
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1MOV
 | | Crystal structure of Coral protein mutant | | 分子名称: | GFP-like non-fluorescent chromoprotein, IODIDE ION | | 著者 | Prescott, M, Ling, M, Beddoe, T, Oakley, A.J, Dove, S, Hoegh-Guldberg, O, Devenish, R.J, Rossjohn, J. | | 登録日 | 2002-09-10 | | 公開日 | 2003-04-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | The 2.2 a crystal structure of a pocilloporin pigment reveals a nonplanar chromophore conformation.
Structure, 11, 2003
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6M83
 | | Crystal structure of TylM1 S120A bound to SAH and dTDP-phenol | | 分子名称: | 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Fick, R.J, McDole, B.G, Trievel, R.C. | | 登録日 | 2018-08-21 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.3685 Å) | | 主引用文献 | Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 58, 2019
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1P0S
 | | Crystal Structure of Blood Coagulation Factor Xa in Complex with Ecotin M84R | | 分子名称: | Coagulation factor X precursor, Ecotin precursor, MAGNESIUM ION, ... | | 著者 | Wang, S.X, Hur, E, Sousa, C.A, Brinen, L, Slivka, E.J, Fletterick, R.J. | | 登録日 | 2003-04-10 | | 公開日 | 2003-08-26 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The Extended Interactions and Gla Domain of Blood Coagulation Factor Xa
Biochemistry, 42, 2003
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6LR6
 | | The crystal structure of human cytoplasmic LRS | | 分子名称: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | | 著者 | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | 登録日 | 2020-01-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.009 Å) | | 主引用文献 | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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7ROX
 | | BthTX-I complexed with inhibitor MMV | | 分子名称: | 12-methoxy-Nb-methylvoachalotine, Basic phospholipase A2 homolog bothropstoxin-I | | 著者 | Borges, R.J, De Marino, I, Uson, I, Fontes, M.R.M. | | 登録日 | 2021-08-02 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and functional studies of a snake venom phospholipase A 2 -like protein complexed to an inhibitor from Tabernaemontana catharinensis.
Biochimie, 206, 2023
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1NA4
 | | The structure of immature Yellow Fever virus particle | | 分子名称: | major envelope protein E | | 著者 | Zhang, Y, Corver, J, Chipman, P.R, Lenches, E, Zhang, W, Pletnev, S.V, Sedlak, D, Baker, T.S, Strauss, J.H, Kuhn, R.J, Rossmann, M.G. | | 登録日 | 2002-11-26 | | 公開日 | 2003-12-09 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY | | 主引用文献 | Structures of immature flavivirus particles
EMBO J., 22, 2003
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2J94
 | | CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | | 分子名称: | 5-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}-1H-1,2,4-TRIAZOLE-3-SULFONAMIDE, CALCIUM ION, COAGULATION FACTOR X | | 著者 | Chan, C, Borthwick, A.D, Brown, D, Campbell, M, Chaudry, L, Chung, C.W, Convery, M.A, Hamblin, J.N, Johnstone, L, Kelly, H.A, Kleanthous, S, Burns-Kurtis, C.L, Patikis, A, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Toomey, J.R, Watson, N.S, Weston, H.E, Whitworth, C, Young, R.J, Zhou, P. | | 登録日 | 2006-11-02 | | 公開日 | 2007-03-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-Morpholin-4-Yl-2-Oxoethyl]-2-Oxopyrrolidin-3-Yl}Sulfonamides.
J.Med.Chem., 50, 2007
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2J70
 | | Structural and functional characterisation of partner-switching regulating the environmental stress response in B. subtilis | | 分子名称: | PHOSPHOSERINE PHOSPHATASE RSBU | | 著者 | Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J. | | 登録日 | 2006-10-05 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
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2J0Z
 | | p53 tetramerization domain wild type | | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | | 著者 | Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. | | 登録日 | 2006-08-08 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Proteins, 71, 2008
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6M82
 | | Crystal structure of TylM1 Y14paF bound to SAH and dTDP-phenol | | 分子名称: | 1,2-ETHANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phenoxy)phosphoryl]oxy}phosphoryl]thymidine, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Fick, R.J, McDole, B.G, Trievel, R.C. | | 登録日 | 2018-08-21 | | 公開日 | 2019-03-13 | | 最終更新日 | 2019-11-27 | | 実験手法 | X-RAY DIFFRACTION (1.3971 Å) | | 主引用文献 | Structural and Functional Characterization of Sulfonium Carbon-Oxygen Hydrogen Bonding in the Deoxyamino Sugar Methyltransferase TylM1.
Biochemistry, 58, 2019
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7S6G
 | | Crystal structure of PhnD from Synechococcus MITS9220 in complex with phosphate | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, PHOSPHATE ION, ... | | 著者 | Shah, B.S, Mikolajek, H, Orr, C.M, Mykhaylyk, V, Owens, R.J, Paulsen, I.T. | | 登録日 | 2021-09-14 | | 公開日 | 2021-10-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Marine picocyanobacterial PhnD1 shows specificity for various phosphorus sources but likely represents a constitutive inorganic phosphate transporter.
Isme J, 17, 2023
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2IUJ
 | | Crystal Structure of Soybean Lipoxygenase-B | | 分子名称: | FE (III) ION, LIPOXYGENASE L-5 | | 著者 | Youn, B, Sellhorn, G.E, Mirchel, R.J, Gaffney, B.J, Grimes, H.D, Kang, C. | | 登録日 | 2006-06-05 | | 公開日 | 2006-10-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structures of Vegetative Soybean Lipoxygenase Vlx-B and Vlx-D, and Comparisons with Seed Isoforms Lox-1 and Lox-3.
Proteins, 65, 2006
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2IPH
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2J6Y
 | | Structural and Functional Characterisation of partner switching regulating the environmental stress response in Bacillus subtilis | | 分子名称: | PHOSPHOSERINE PHOSPHATASE RSBU | | 著者 | Hardwick, S.W, Pane-Farre, J, Delumeau, O, Marles-Wright, J, Murray, J.W, Hecker, M, Lewis, R.J. | | 登録日 | 2006-10-05 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural and functional characterization of partner switching regulating the environmental stress response in Bacillus subtilis.
J. Biol. Chem., 282, 2007
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1PC2
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5MWF
 | | Human Jagged2 C2-EGF2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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2J11
 | | p53 tetramerization domain mutant Y327S T329G Q331G | | 分子名称: | CELLULAR TUMOR ANTIGEN P53 | | 著者 | Carbajo, R.J, Mora, P, Sanchez del Pino, M.M, Perez-Paya, E, Pineda-Lucena, A. | | 登録日 | 2006-08-08 | | 公開日 | 2007-08-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solvent-exposed residues located in the beta-sheet modulate the stability of the tetramerization domain of p53--a structural and combinatorial approach.
Proteins, 71, 2008
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2IHL
 | | LYSOZYME (E.C.3.2.1.17) (JAPANESE QUAIL) | | 分子名称: | JAPANESE QUAIL EGG WHITE LYSOZYME, SODIUM ION | | 著者 | Houdusse, A, Bentley, G.A, Poljak, R.J, Souchon, H, Zhang, Z. | | 登録日 | 1993-06-29 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Three-dimensional structure of a heteroclitic antigen-antibody cross-reaction complex.
Proc.Natl.Acad.Sci.Usa, 90, 1993
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2JH5
 | | Human Thrombin Hirugen Inhibitor complex | | 分子名称: | 2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}ETHENESULFONAMIDE, CALCIUM ION, HIRUDIN IIIA, ... | | 著者 | Senger, S, Chan, C, Convery, M.A, Hubbard, J.A, Young, R.J, Shah, G.P, Watson, N.S. | | 登録日 | 2007-02-20 | | 公開日 | 2007-05-08 | | 最終更新日 | 2017-06-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design.
Bioorg.Med.Chem.Lett., 17, 2007
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2JH0
 | | Human Thrombin Hirugen Inhibitor complex | | 分子名称: | (2R)-2-(5-CHLORO-2-THIENYL)-N-{(3S)-1-[(1S)-1-METHYL-2-MORPHOLIN-4-YL-2-OXOETHYL]-2-OXOPYRROLIDIN-3-YL}PROPENE-1-SULFONAMIDE, CALCIUM ION, HIRUDIN IIIA, ... | | 著者 | Senger, S, Chan, C, Convery, M.A, Hubbard, J.A, Young, R.J, Shah, G.P, Watson, N.S. | | 登録日 | 2007-02-19 | | 公開日 | 2007-05-08 | | 最終更新日 | 2013-08-07 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Sulfonamide-Related Conformational Effects and Their Importance in Structure-Based Design.
Bioorg.Med.Chem.Lett., 17, 2007
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5MW5
 | | Human Jagged2 C2-EGF2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protein jagged-2 | | 著者 | Suckling, R.J, Handford, P.A, Lea, S.M. | | 登録日 | 2017-01-18 | | 公開日 | 2017-06-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and functional dissection of the interplay between lipid and Notch binding by human Notch ligands.
EMBO J., 36, 2017
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5N11
 | | Crystal structure of Human beta1-coronavirus OC43 NL/A/2005 Hemagglutinin-Esterase | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | | 著者 | Bakkers, M.J.G, Feitsma, L.J, de Groot, R.J, Huizinga, E.G. | | 登録日 | 2017-02-04 | | 公開日 | 2017-03-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Betacoronavirus Adaptation to Humans Involved Progressive Loss of Hemagglutinin-Esterase Lectin Activity.
Cell Host Microbe, 21, 2017
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