5DF9
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![BU of 5df9 by Molmil](/molmil-images/mine/5df9) | CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 IN COMPLEX WITH DEACYLATED PRODUCT OF CEFOPERAZONE | Descriptor: | (2R,5R)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}methyl]-5-methyl-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Cell division protein, GLYCEROL, ... | Authors: | Ren, J, Nettleship, J.E, Males, A, Stuart, D.I, Owens, R.J. | Deposit date: | 2015-08-26 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590, 2016
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5CXX
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![BU of 5cxx by Molmil](/molmil-images/mine/5cxx) | Structure of a CE1 ferulic acid esterase, AmCE1/Fae1A, from Anaeromyces mucronatus in complex with Ferulic acid | Descriptor: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, GLYCEROL, SULFATE ION, ... | Authors: | Gruninger, R.J, Abbott, D.W. | Deposit date: | 2015-07-29 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Contributions of a unique beta-clamp to substrate recognition illuminates the molecular basis of exolysis in ferulic acid esterases. Biochem.J., 473, 2016
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4NX8
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![BU of 4nx8 by Molmil](/molmil-images/mine/4nx8) | Structure of a PTP-like phytase from Bdellovibrio bacteriovorus | Descriptor: | GLYCEROL, MAGNESIUM ION, Protein-tyrosine phosphatase 2 | Authors: | Gruninger, R.J, Lovering, A.L. | Deposit date: | 2013-12-08 | Release date: | 2014-07-23 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.698 Å) | Cite: | Structural and biochemical analysis of a unique phosphatase from Bdellovibrio bacteriovorus reveals its structural and functional relationship with the protein tyrosine phosphatase class of phytase. Plos One, 9, 2014
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2F11
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![BU of 2f11 by Molmil](/molmil-images/mine/2f11) | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor | Descriptor: | 2-methylpropyl 2-acetamido-2,4-dideoxy-alpha-L-threo-hex-4-enopyranosiduronic acid, PHOSPHATE ION, Sialidase 2 | Authors: | Chavas, L.M.G, Kato, R, Mann, M.C, Thomson, R.J, Dyason, J.C, von Itzstein, M, Fusi, P, Tringali, C, Venerando, B, Tettamanti, G, Monti, E, Wakatsuki, S. | Deposit date: | 2005-11-14 | Release date: | 2006-11-21 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Crystal Structure of the Human Sialidase Neu2 in Complex with isobutyl ether mimetic Inhibitor To be Published
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3R1G
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![BU of 3r1g by Molmil](/molmil-images/mine/3r1g) | Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody | Descriptor: | Beta-secretase 1, FAB of YW412.8.31 antibody heavy chain, FAB of YW412.8.31 antibody light chain | Authors: | Wang, W, Rouge, L, Wu, P, Chiu, C, Chen, Y, Wu, Y, Watts, R.J. | Deposit date: | 2011-03-10 | Release date: | 2011-06-08 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-{beta} Production in Vivo. Sci Transl Med, 3, 2011
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4N6U
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![BU of 4n6u by Molmil](/molmil-images/mine/4n6u) | Adhiron: a stable and versatile peptide display scaffold - truncated adhiron | Descriptor: | Adhiron | Authors: | Mcpherson, M, Tomlinson, D, Owen, R.L, Nettleship, J.E, Owens, R.J. | Deposit date: | 2013-10-14 | Release date: | 2014-04-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Adhiron: a stable and versatile peptide display scaffold for molecular recognition applications. Protein Eng.Des.Sel., 27, 2014
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4MYL
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![BU of 4myl by Molmil](/molmil-images/mine/4myl) | |
3SKU
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![BU of 3sku by Molmil](/molmil-images/mine/3sku) | Herpes simplex virus glycoprotein D bound to the human receptor nectin-1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein D, ... | Authors: | Di Giovine, P, Settembre, E.C, Bhargava, A.K, Luftig, M.A, Lou, H, Cohen, G.H, Eisenberg, R.J, Krummenacher, C, Carfi, A. | Deposit date: | 2011-06-23 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Structure of herpes simplex virus glycoprotein d bound to the human receptor nectin-1. Plos Pathog., 7, 2011
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3TJG
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![BU of 3tjg by Molmil](/molmil-images/mine/3tjg) | Crystal Structure of human peroxiredoxin IV C51A mutant in oxidized form | Descriptor: | Peroxiredoxin-4 | Authors: | Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. | Deposit date: | 2011-08-24 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle. J.Biol.Chem., 286, 2011
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3OKE
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![BU of 3oke by Molmil](/molmil-images/mine/3oke) | Crystal structure of S25-39 in complex with Ko | Descriptor: | S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain, ZINC ION, ... | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-24 | Release date: | 2011-04-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3U6C
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![BU of 3u6c by Molmil](/molmil-images/mine/3u6c) | MutM set 1 ApGo | Descriptor: | DNA (5'-D(*GP*GP*TP*AP*GP*AP*TP*CP*CP*TP*GP*AP*C)-3'), DNA (5'-D(P*CP*AP*(8OG)P*GP*AP*(TX)P*CP*TP*AP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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2F2J
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![BU of 2f2j by Molmil](/molmil-images/mine/2f2j) | |
2F4S
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![BU of 2f4s by Molmil](/molmil-images/mine/2f4s) | A-site RNA in complex with neamine | Descriptor: | (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, 5'-R(P*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | Deposit date: | 2005-11-24 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site Chem.Biol., 13, 2006
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3OKM
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![BU of 3okm by Molmil](/molmil-images/mine/3okm) | Crystal structure of unliganded S25-39 | Descriptor: | S25-39 Fab (IgG1k) heavy chain, S25-39 Fab (IgG1k) light chain | Authors: | Blackler, R.J, Evans, S.V. | Deposit date: | 2010-08-25 | Release date: | 2011-04-06 | Last modified: | 2018-03-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A Common NH53K Mutation in the Combining Site of Antibodies Raised against Chlamydial LPS Glycoconjugates Significantly Increases Avidity. Biochemistry, 50, 2011
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3OLO
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![BU of 3olo by Molmil](/molmil-images/mine/3olo) | Crystal structure of a PAS domain from two-component sensor histidine kinase | Descriptor: | GLYCEROL, Two-component sensor histidine kinase | Authors: | Michalska, K, Chhor, G, Bearden, J, Fenske, R.J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2010-08-26 | Release date: | 2010-09-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.094 Å) | Cite: | Crystal structure of a PAS domain from two-component sensor histidine kinase To be Published
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3U6S
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![BU of 3u6s by Molmil](/molmil-images/mine/3u6s) | MutM set 1 TpG | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*AP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*TP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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3TJK
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![BU of 3tjk by Molmil](/molmil-images/mine/3tjk) | Crystal Structure of human peroxiredoxin IV C245A mutant in reduced form | Descriptor: | Peroxiredoxin-4 | Authors: | Cao, Z, Tavender, T.J, Roszak, A.W, Cogdell, R.J, Bulleid, N.J. | Deposit date: | 2011-08-24 | Release date: | 2011-10-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Crystal Structure of Reduced and of Oxidized Peroxiredoxin IV Enzyme Reveals a Stable Oxidized Decamer and a Non-disulfide-bonded Intermediate in the Catalytic Cycle. J.Biol.Chem., 286, 2011
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3U6D
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![BU of 3u6d by Molmil](/molmil-images/mine/3u6d) | MutM set 1 GpGo | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*CP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*GP*(8OG)P*GP*AP*(TX)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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3QEF
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![BU of 3qef by Molmil](/molmil-images/mine/3qef) | The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases | Descriptor: | 1,2-ETHANEDIOL, Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, ... | Authors: | Cartmell, A, Mckee, L.S, Pena, M, Larsbrink, J, Brumer, H, Lewis, R.J, Viks-Nielsen, A, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-01-20 | Release date: | 2011-02-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.789 Å) | Cite: | The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases. J.Biol.Chem., 286, 2011
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2F4T
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![BU of 2f4t by Molmil](/molmil-images/mine/2f4t) | Asite RNA + designer antibiotic | Descriptor: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, 5'-R(*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3', 5'-R(*UP*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3' | Authors: | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | Deposit date: | 2005-11-24 | Release date: | 2006-05-02 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Interactions of designer antibiotics and the bacterial ribosomal aminoacyl-tRNA site Chem.Biol., 13, 2006
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3QJX
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![BU of 3qjx by Molmil](/molmil-images/mine/3qjx) | Crystal Structure of E. coli Aminopeptidase N in complex with L-Serine | Descriptor: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | Authors: | Addlagatta, A, Gumpena, R, Kishor, C, Ganji, R.J. | Deposit date: | 2011-01-31 | Release date: | 2011-11-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases Chemmedchem, 6, 2011
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3PZ6
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![BU of 3pz6 by Molmil](/molmil-images/mine/3pz6) | The crystal structure of GlLeuRS-CP1 | Descriptor: | Leucyl-tRNA synthetase | Authors: | Liu, R.J, Du, D.H, Wang, E.D. | Deposit date: | 2010-12-14 | Release date: | 2011-08-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase Biochem.J., 440, 2011
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3U6P
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![BU of 3u6p by Molmil](/molmil-images/mine/3u6p) | MutM set 1 GpG | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*CP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*GP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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3U6O
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![BU of 3u6o by Molmil](/molmil-images/mine/3u6o) | MutM set 1 ApG | Descriptor: | DNA (5'-D(*A*GP*GP*TP*AP*GP*AP*TP*CP*CP*TP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*AP*GP*GP*AP*(08Q)P*CP*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2013-09-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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3U6L
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![BU of 3u6l by Molmil](/molmil-images/mine/3u6l) | MutM set 2 CpGo | Descriptor: | DNA (5'-D(*AP*GP*GP*TP*AP*GP*AP*CP*CP*GP*GP*AP*CP*GP*C)-3'), DNA (5'-D(*TP*GP*CP*GP*TP*CP*CP*(8OG)P*GP*TP*(CX2)P*TP*AP*CP*C)-3'), Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Qi, Y, Verdine, G.L. | Deposit date: | 2011-10-12 | Release date: | 2012-04-25 | Last modified: | 2017-01-11 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Sequence-dependent structural variation in DNA undergoing intrahelical inspection by the DNA glycosylase MutM. J.Biol.Chem., 287, 2012
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