2D55
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![BU of 2d55 by Molmil](/molmil-images/mine/2d55) | Structural, physical and biological characteristics of RNA.DNA binding agent N8-actinomycin D | 分子名称: | ACTINOMYCIN D, DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3') | 著者 | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | 登録日 | 1995-05-01 | 公開日 | 1995-10-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of the 2:1 Complex between D(Gaagcttc) and the Anticancer Drug Actinomycin D. J.Mol.Biol., 225, 1992
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209D
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![BU of 209d by Molmil](/molmil-images/mine/209d) | Structural, physical and biological characteristics of RNA:DNA binding agent N8-actinomycin D | 分子名称: | DNA (5'-D(*GP*AP*AP*GP*CP*TP*TP*C)-3'), N8-ACTINOMYCIN D | 著者 | Shinomiya, M, Chu, W, Carlson, R.G, Weaver, R.F, Takusagawa, F. | 登録日 | 1995-05-01 | 公開日 | 1995-10-15 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural, Physical, and Biological Characteristics of RNA.DNA Binding Agent N8-Actinomycin D. Biochemistry, 34, 1995
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4V40
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![BU of 4v40 by Molmil](/molmil-images/mine/4v40) | BETA-GALACTOSIDASE | 分子名称: | BETA-GALACTOSIDASE, MAGNESIUM ION | 著者 | Jacobson, R.H, Zhang, X, Dubose, R.F, Matthews, B.W. | 登録日 | 1994-07-18 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Three-dimensional structure of beta-galactosidase from E. coli. Nature, 369, 1994
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8E8O
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![BU of 8e8o by Molmil](/molmil-images/mine/8e8o) | Cryo-EM structure of human ME3 in the presence of citrate | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent malic enzyme, mitochondrial | 著者 | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | 登録日 | 2022-08-25 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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8E76
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![BU of 8e76 by Molmil](/molmil-images/mine/8e76) | Cryo-EM structure of Apo form ME3 | 分子名称: | NADP-dependent malic enzyme, mitochondrial | 著者 | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | 登録日 | 2022-08-23 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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8E78
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![BU of 8e78 by Molmil](/molmil-images/mine/8e78) | Cryo-EM structure of human ME3 in the presence of citrate | 分子名称: | NADP-dependent malic enzyme, mitochondrial | 著者 | Yu, X, Grell, T.A.J, Shaffer, P.L, Steele, R, Sharma, S, Thompson, A.A, Tresadern, G, Ortiz-Meoz, R.F, Mason, M, Gomez-Tamayo, J.C, Riley, D, Wagner, M.V, Wadia, J. | 登録日 | 2022-08-23 | 公開日 | 2023-02-08 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Integrative structural and functional analysis of human malic enzyme 3: A potential therapeutic target for pancreatic cancer. Heliyon, 8, 2022
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6EJF
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4XH3
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6F8L
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5C53
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![BU of 5c53 by Molmil](/molmil-images/mine/5c53) | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | 登録日 | 2015-06-19 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.567 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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4V6Q
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![BU of 4v6q by Molmil](/molmil-images/mine/4v6q) | Structural characterization of mRNA-tRNA translocation intermediates (class 5 of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-08 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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4V6R
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![BU of 4v6r by Molmil](/molmil-images/mine/4v6r) | Structural characterization of mRNA-tRNA translocation intermediates (class 6 of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-08 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (11.5 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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4V6N
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![BU of 4v6n by Molmil](/molmil-images/mine/4v6n) | Structural characterization of mRNA-tRNA translocation intermediates (50S ribosome of class2 of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (12.1 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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6GDI
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![BU of 6gdi by Molmil](/molmil-images/mine/6gdi) | Structure of P-glycoprotein(ABCB1) in the post-hydrolytic state | 分子名称: | Multidrug resistance protein 1A | 著者 | Ford, R.C, Thonghin, N, Collins, R.F, Barbieri, A, Shafi, T, Siebert, A. | 登録日 | 2018-04-23 | 公開日 | 2018-05-23 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9 angstrom resolution. Bmc Struct.Biol., 18, 2018
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7LMT
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![BU of 7lmt by Molmil](/molmil-images/mine/7lmt) | Histone-lysine N-methyltransferase NSD2-PWWP1 with compound MRT10241866a | 分子名称: | Histone-lysine N-methyltransferase NSD2, UNKNOWN ATOM OR ION, ~{N}-cyclopropyl-3-oxidanylidene-~{N}-(thiophen-2-ylmethyl)-4~{H}-1,4-benzoxazine-7-carboxamide | 著者 | Lei, M, Freitas, R.F, Dong, A, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2021-02-05 | 公開日 | 2021-03-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Histone-lysine N-methyltransferase NSD2-PWWP1 with compound MRT10241866a To Be Published
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4YND
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![BU of 4ynd by Molmil](/molmil-images/mine/4ynd) | The Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2 | 分子名称: | N-cyclohexyl-N~3~-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[(2R)-2-hydroxy-2-(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide, N-lysine methyltransferase SMYD2, S-ADENOSYLMETHIONINE, ... | 著者 | Sweis, R.F, Wang, Z, Algire, M, Arrowsmith, C.H, Brown, P.J, Chiang, G.C, Guo, J, Jakob, C.G, Kennedy, S, Li, F, Soni, N.B, Vedadi, M, Pappano, W.N. | 登録日 | 2015-03-09 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2. Acs Med.Chem.Lett., 6, 2015
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7KQ4
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7KQ3
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5C51
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![BU of 5c51 by Molmil](/molmil-images/mine/5c51) | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y. | 登録日 | 2015-06-19 | 公開日 | 2016-05-11 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (3.426 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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5C52
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![BU of 5c52 by Molmil](/molmil-images/mine/5c52) | Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | 登録日 | 2015-06-19 | 公開日 | 2016-05-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.637 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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2K9S
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2P8O
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![BU of 2p8o by Molmil](/molmil-images/mine/2p8o) | Crystal Structure of a Benzohydroxamic Acid/Vanadate complex bound to chymotrypsin A | 分子名称: | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... | 著者 | Moulin, A, Bell, J.H, Pratt, R.F, Ringe, D. | 登録日 | 2007-03-22 | 公開日 | 2007-05-08 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Inhibition of chymotrypsin by a complex of ortho-vanadate and benzohydroxamic Acid: structure of the inert complex and its mechanistic interpretation. Biochemistry, 46, 2007
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2P9V
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![BU of 2p9v by Molmil](/molmil-images/mine/2p9v) | Structure of AmpC beta-lactamase with cross-linked active site after exposure to small molecule inhibitor | 分子名称: | Beta-lactamase, PHOSPHATE ION | 著者 | Babaoglu, K, Wyrembak, P.N, Pelto, R.B, Shoichet, B.K, Pratt, R.F. | 登録日 | 2007-03-26 | 公開日 | 2007-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | O-Aryloxycarbonyl Hydroxamates: New beta-Lactamase Inhibitors That Cross-Link the Active Site. J.Am.Chem.Soc., 129, 2007
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4V6L
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![BU of 4v6l by Molmil](/molmil-images/mine/4v6l) | Structural insights into cognate vs. near-cognate discrimination during decoding. | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Agirrezabala, X, Schreiner, E, Trabuco, L.G, Lei, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-01-07 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (13.2 Å) | 主引用文献 | Structural insights into cognate versus near-cognate discrimination during decoding. Embo J., 30, 2011
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4V6S
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![BU of 4v6s by Molmil](/molmil-images/mine/4v6s) | Structural characterization of mRNA-tRNA translocation intermediates (class 3 of the six classes) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. | 登録日 | 2011-12-09 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (13.1 Å) | 主引用文献 | Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
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