6U4B
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![BU of 6u4b by Molmil](/molmil-images/mine/6u4b) | WbbM bifunctional glycosytransferase apo structure | Descriptor: | MAGNESIUM ION, WbbM protein | Authors: | Kimber, M.S, Mallette, E, Kamski-Hennekam, E.R, Gitalis, R. | Deposit date: | 2019-08-25 | Release date: | 2020-01-22 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family. Nat.Chem.Biol., 16, 2020
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3BKP
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![BU of 3bkp by Molmil](/molmil-images/mine/3bkp) | Crystal structure of the Toxoplasma gondii cyclophilin, 49.m03261 | Descriptor: | Cyclophilin, GLYCEROL | Authors: | Wernimont, A.K, Lew, J, Kozieradzki, I, Lin, Y.H, Sun, X, Khuu, C, Zhao, Y, Schapira, M, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bochkarev, A, Hui, R, Artz, J.D, Amani, M, Structural Genomics Consortium (SGC) | Deposit date: | 2007-12-07 | Release date: | 2007-12-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the Toxoplasma gondii cyclophilin, 49.m03261. To be Published
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6U4Q
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![BU of 6u4q by Molmil](/molmil-images/mine/6u4q) | Carbonic anhydrase 2 in complex with SB4197 | Descriptor: | 4-methyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | Authors: | Murray, A.B, Lomelino, C.L, McKenna, R. | Deposit date: | 2019-08-26 | Release date: | 2020-01-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.306 Å) | Cite: | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
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5HP5
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![BU of 5hp5 by Molmil](/molmil-images/mine/5hp5) | Srtucture of human peptidylarginine deiminase type I (PAD1) | Descriptor: | CALCIUM ION, Protein-arginine deiminase type-1 | Authors: | Unno, M, Nagai, A, Saijo, S, Shimizu, N, Kinjo, S, Mashimo, R, Kizawa, K, Takahara, H. | Deposit date: | 2016-01-20 | Release date: | 2016-07-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.198 Å) | Cite: | Monomeric Form of Peptidylarginine Deiminase Type I Revealed by X-ray Crystallography and Small-Angle X-ray Scattering J.Mol.Biol., 428, 2016
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3BT4
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![BU of 3bt4 by Molmil](/molmil-images/mine/3bt4) | Crystal Structure Analysis of AmFPI-1, fungal protease inhibitor from Antheraea mylitta | Descriptor: | Fungal protease inhibitor-1, GLYCEROL | Authors: | Roy, S, Aravind, P, Madhurantakam, C, Ghosh, A.K, Sankarananarayanan, R, Das, A.K. | Deposit date: | 2007-12-27 | Release date: | 2008-12-30 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of a fungal protease inhibitor from Antheraea mylitta J.Struct.Biol., 166, 2009
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6U83
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![BU of 6u83 by Molmil](/molmil-images/mine/6u83) | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D-ALANINE, Outer membrane associated protein, ... | Authors: | Michalska, K, Skarina, T, Stogios, P.J, Di Leo, R, Savchenko, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-09-04 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.3566 Å) | Cite: | OmpA-like domain of FopA1 from Francisella tularensis subsp. tularensis SCHU S4 To Be Published
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6UB9
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![BU of 6ub9 by Molmil](/molmil-images/mine/6ub9) | Crystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORM | Descriptor: | (2R,3S,4R)-3-(4'-chloro-2',6'-difluoro[1,1'-biphenyl]-4-yl)-4-(fluoromethyl)azetidine-2-carbonitrile, 1,2-ETHANEDIOL, 2-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]ACRYLIC ACID, ... | Authors: | Chang, C, Michalska, K, Maltseva, N.I, Jedrzejczak, R, McCarren, P, Nag, P.P, Joachimiak, A, Satchell, K, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-09-11 | Release date: | 2019-09-25 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.783 Å) | Cite: | Crystal structure of tryptophan synthase from M. tuberculosis - AMINOACRYLATE- AND BRD6309-BOUND FORM To be Published
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5HDY
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![BU of 5hdy by Molmil](/molmil-images/mine/5hdy) | |
3BSZ
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![BU of 3bsz by Molmil](/molmil-images/mine/3bsz) | Crystal structure of the transthyretin-retinol binding protein-Fab complex | Descriptor: | Fab fragment heavy chain, Fab fragment light chain, Plasma retinol-binding protein, ... | Authors: | Zanotti, G, Cendron, L, Gliubich, F, Folli, C, Berni, R. | Deposit date: | 2007-12-27 | Release date: | 2008-11-11 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.38 Å) | Cite: | Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein. Febs J., 275, 2008
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6UEY
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![BU of 6uey by Molmil](/molmil-images/mine/6uey) | Pistol ribozyme transition-state analog vanadate | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER) | Authors: | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | Deposit date: | 2019-09-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
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6UFJ
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![BU of 6ufj by Molmil](/molmil-images/mine/6ufj) | Pistol ribozyme product crystal structure | Descriptor: | MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ... | Authors: | Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R. | Deposit date: | 2019-09-24 | Release date: | 2019-12-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.645 Å) | Cite: | Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme. Angew.Chem.Int.Ed.Engl., 59, 2020
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5H6L
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![BU of 5h6l by Molmil](/molmil-images/mine/5h6l) | DNA targeting ADP-ribosyltransferase Pierisin-1 in complex with beta-NAD+ | Descriptor: | 1,2-ETHANEDIOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pierisin-1 | Authors: | Oda, T, Hirabayashi, H, Shikauchi, G, Takamura, R, Hiraga, K, Minami, H, Hashimoto, H, Yamamoto, M, Wakabayashi, K, Sugimura, T, Shimizu, T, Sato, M. | Deposit date: | 2016-11-14 | Release date: | 2017-08-09 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of autoinhibition and activation of the DNA-targeting ADP-ribosyltransferase pierisin-1 J. Biol. Chem., 292, 2017
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3BW9
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![BU of 3bw9 by Molmil](/molmil-images/mine/3bw9) | Crystal Structure of HLA B*3508 in complex with a HCMV 12-mer peptide from the pp65 protein | Descriptor: | Beta-2-microglobulin, CPS peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ... | Authors: | Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R. | Deposit date: | 2008-01-08 | Release date: | 2008-04-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection Blood, 111, 2008
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6UGZ
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![BU of 6ugz by Molmil](/molmil-images/mine/6ugz) | Human Carbonic Anhydrase IX-mimic complexed with SB4-208 | Descriptor: | 7-fluoro-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase IX-mimic, ZINC ION | Authors: | Murray, A.B, Lomelino, C.L, McKenna, R. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.306 Å) | Cite: | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
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5HEL
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![BU of 5hel by Molmil](/molmil-images/mine/5hel) | Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2 | Descriptor: | 1,2-ETHANEDIOL, Bromodomain-containing protein 2 | Authors: | Tallant, C, Lori, C, Pasquo, A, Chiaraluce, R, Consalvi, V, Newman, J.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S. | Deposit date: | 2016-01-06 | Release date: | 2016-01-20 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2 To Be Published
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6UHT
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![BU of 6uht by Molmil](/molmil-images/mine/6uht) | |
5HEO
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![BU of 5heo by Molmil](/molmil-images/mine/5heo) | |
5E3E
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![BU of 5e3e by Molmil](/molmil-images/mine/5e3e) | Crystal structure of CdiA-CT/CdiI complex from Y. kristensenii 33638 | Descriptor: | CdiI immunity protein, Large exoprotein involved in heme utilization or adhesion, SODIUM ION | Authors: | Michalska, K, Joachimiak, G, Jedrzejczak, R, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2015-10-02 | Release date: | 2015-11-25 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The CDI toxin of Yersinia kristensenii is a novel bacterial member of the RNase A superfamily. Nucleic Acids Res., 45, 2017
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5DUN
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![BU of 5dun by Molmil](/molmil-images/mine/5dun) | The crystal structure of OMe substituted twister ribozyme | Descriptor: | MAGNESIUM ION, POTASSIUM ION, RNA (54-MER) | Authors: | Ren, A, Patel, D.J, Micura, R, Rajashankar, K.R. | Deposit date: | 2015-09-19 | Release date: | 2015-10-28 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | A Mini-Twister Variant and Impact of Residues/Cations on the Phosphodiester Cleavage of this Ribozyme Class. Angew.Chem.Int.Ed.Engl., 54, 2015
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5DVM
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![BU of 5dvm by Molmil](/molmil-images/mine/5dvm) | Fc Design 20.8.37 B chain homodimer E357D/S364R/Y407A | Descriptor: | Fc-III peptide, Ig gamma-1 chain C region | Authors: | Atwell, S, Leaver-Fay, A, Froning, K.J, Aldaz, H, Pustilnik, A, Lu, F, Huang, F, Yuan, R, Dhanani, S.H, Chamberlain, A.K, Fitchett, J.R, Gutierrez, B, Hendle, J, Demarest, S.J, Kuhlman, B. | Deposit date: | 2015-09-21 | Release date: | 2016-03-30 | Last modified: | 2016-07-06 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Computationally Designed Bispecific Antibodies using Negative State Repertoires. Structure, 24, 2016
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6UE2
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![BU of 6ue2 by Molmil](/molmil-images/mine/6ue2) | 1.85 Angstrom Resolution Crystal Structure of Class D beta-lactamase from Clostridium difficile 630 | Descriptor: | Beta-lactamase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Minasov, G, Shuvalova, L, Dubrovska, I, Rosas-Lemus, M, Jedrzejczak, R, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-09-20 | Release date: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | 1.85 Angstrom Resolution Crystal Structure of Class D beta-lactamase from Clostridium difficile 630. To Be Published
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5E5V
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![BU of 5e5v by Molmil](/molmil-images/mine/5e5v) | Structure of amyloid forming peptide NFGAILS (residues 22-28) from Islet Amyloid Polypeptide | Descriptor: | NFGAILS (22-28) from islet amyloid polypeptide, synthesized | Authors: | Soriaga, A.B, Macdonald, R, Sawaya, M.R, Sangwan, S, Eisenberg, D. | Deposit date: | 2015-10-09 | Release date: | 2015-12-16 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets. J.Phys.Chem.B, 120, 2016
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6UGN
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![BU of 6ugn by Molmil](/molmil-images/mine/6ugn) | Human Carbonic Anhydrase 2 complexed with SB4-205 | Descriptor: | 5,7-dimethyl-1lambda~6~,2,4-benzothiadiazine-1,1,3(2H,4H)-trione, Carbonic anhydrase 2, ZINC ION | Authors: | Murray, A.B, Supuran, C.T, McKenna, R. | Deposit date: | 2019-09-26 | Release date: | 2019-12-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.406 Å) | Cite: | "A Sweet Combination": Developing Saccharin and Acesulfame K Structures for Selectively Targeting the Tumor-Associated Carbonic Anhydrases IX and XII. J.Med.Chem., 63, 2020
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6UI6
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![BU of 6ui6 by Molmil](/molmil-images/mine/6ui6) | HBV T=3 149C3A | Descriptor: | Core protein | Authors: | Wu, W, Watts, N.R, Cheng, N, Huang, R, Steven, A, Wingfield, P.T. | Deposit date: | 2019-09-30 | Release date: | 2019-11-06 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Expression of quasi-equivalence and capsid dimorphism in the Hepadnaviridae. Plos Comput.Biol., 16, 2020
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5DXR
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![BU of 5dxr by Molmil](/molmil-images/mine/5dxr) | Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol | Descriptor: | 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2 | Authors: | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | Deposit date: | 2015-09-23 | Release date: | 2016-05-04 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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