8IAW
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8IAU
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![BU of 8iau by Molmil](/molmil-images/mine/8iau) | Crystal structure of Streptococcus pneumoniae pyruvate kinase in complex with oxalate and fructose 1,6-bisphosphate | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | Authors: | Nakashima, R, Taguchi, A. | Deposit date: | 2023-02-09 | Release date: | 2023-06-14 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Functional and structural characterization of Streptococcus pneumoniae pyruvate kinase involved in fosfomycin resistance. J.Biol.Chem., 299, 2023
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8IAV
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6LVB
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![BU of 6lvb by Molmil](/molmil-images/mine/6lvb) | Structure of Dimethylformamidase, tetramer | Descriptor: | FE (III) ION, N,N-dimethylformamidase large subunit, N,N-dimethylformamidase small subunit | Authors: | Arya, C.A, Yadav, S, Fine, J, Casanal, A, Chopra, G, Ramanathan, G, Subramanian, R, Vinothkumar, K.R. | Deposit date: | 2020-02-02 | Release date: | 2020-06-03 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase. Angew.Chem.Int.Ed.Engl., 59, 2020
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3TOA
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![BU of 3toa by Molmil](/molmil-images/mine/3toa) | Human MOF crystal structure with active site lysine partially acetylated | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, ZINC ION, ... | Authors: | Yuan, H, Ding, E.C, Marmorstein, R. | Deposit date: | 2011-09-04 | Release date: | 2011-11-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | MYST protein acetyltransferase activity requires active site lysine autoacetylation. Embo J., 31, 2011
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4KDY
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![BU of 4kdy by Molmil](/molmil-images/mine/4kdy) | Crystal structure of maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, Target EFI-507175, with bound GSH in the active site | Descriptor: | CITRIC ACID, GLUTATHIONE, GLYCEROL, ... | Authors: | Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Stead, M, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-04-25 | Release date: | 2013-05-08 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Crystal structure of maleylacetoacetate isomerase from Anaeromyxobacter dehalogenans 2CP-1, Target EFI-507175, with bound GSH in the active site To be Published
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5OC9
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![BU of 5oc9 by Molmil](/molmil-images/mine/5oc9) | Crystal Structure of human TMEM16K / Anoctamin 10 | Descriptor: | (2R)-2,3-dihydroxypropyl (7Z)-hexadec-7-enoate, Anoctamin-10, CALCIUM ION | Authors: | Bushell, S.R, Pike, A.C.W, Chu, A, Tessitore, A, Rotty, B, Mukhopadhyay, S, Kupinska, K, Shrestha, L, Borkowska, O, Chalk, R, Burgess-Brown, N.A, Love, J, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2017-06-29 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10, 2019
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3UO2
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![BU of 3uo2 by Molmil](/molmil-images/mine/3uo2) | Jac1 co-chaperone from Saccharomyces cerevisiae | Descriptor: | J-type co-chaperone JAC1, mitochondrial | Authors: | Osipiuk, J, Mulligan, R, Bigelow, L, Marszalek, J, Craig, E.A, Dutkiewicz, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-11-16 | Release date: | 2011-12-14 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Interaction of j-protein co-chaperone jac1 with fe-s scaffold isu is indispensable in vivo and conserved in evolution. J.Mol.Biol., 417, 2012
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1HBY
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![BU of 1hby by Molmil](/molmil-images/mine/1hby) | Binding of Phosphate and Pyrophosphate ions at the active site of human angiogenin as revealed by X-ray Crystallography | Descriptor: | ANGIOGENIN, PHOSPHATE ION | Authors: | Leonidas, D.D, Chavali, G.B, Jardine, A.S, Li, S, Shapiro, R, Acharya, K.R. | Deposit date: | 2001-04-21 | Release date: | 2001-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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8HUK
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![BU of 8huk by Molmil](/molmil-images/mine/8huk) | X-ray structure of human PPAR alpha ligand binding domain-lanifibranor-SRC1 coactivator peptide co-crystals obtained by soaking | Descriptor: | 15-meric peptide from Nuclear receptor coactivator 1, 4-[1-(1,3-benzothiazol-6-ylsulfonyl)-5-chloro-indol-2-yl]butanoic acid, Peroxisome proliferator-activated receptor alpha | Authors: | Kamata, S, Ishikawa, R, Akahane, M, Honda, A, Oyama, T, Ishii, I. | Deposit date: | 2022-12-24 | Release date: | 2023-08-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.981 Å) | Cite: | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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3TO6
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8HUQ
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![BU of 8huq by Molmil](/molmil-images/mine/8huq) | X-ray structure of human PPAR alpha ligand binding domain-elafibranor-SRC1 coactivator peptide co-crystals obtained by soaking | Descriptor: | 15-meric peptide from Nuclear receptor coactivator 1, 2-[2,6-dimethyl-4-[(~{E})-3-(4-methylsulfanylphenyl)-3-oxidanylidene-prop-1-enyl]phenoxy]-2-methyl-propanoic acid, GLYCEROL, ... | Authors: | Kamata, S, Ishikawa, R, Akahane, M, Honda, A, Oyama, T, Ishii, I. | Deposit date: | 2022-12-24 | Release date: | 2023-08-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Functional and Structural Insights into the Human PPAR alpha / delta / gamma Targeting Preferences of Anti-NASH Investigational Drugs, Lanifibranor, Seladelpar, and Elafibranor. Antioxidants, 12, 2023
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6NB8
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![BU of 6nb8 by Molmil](/molmil-images/mine/6nb8) | Crystal structure of anti- SARS-CoV human neutralizing S230 antibody Fab fragment | Descriptor: | S230 antigen-binding (Fab) fragment, heavy chain, light chain | Authors: | Walls, A.J, Xiong, X, Park, Y.J, Tortorici, M.A, Snijder, J, Quispe, J, Cameroni, E, Gopal, R, Dai, M, Lanzavecchia, A, Zambon, M, Rey, F.A, Corti, D, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | Deposit date: | 2018-12-06 | Release date: | 2019-02-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion. Cell, 176, 2019
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4AJJ
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![BU of 4ajj by Molmil](/molmil-images/mine/4ajj) | rat LDHA in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid and N-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido-propanamide | Descriptor: | 2-((3,4-DIMETHOXYPHENYL)METHYL))PROPANEDIOIC ACID, DIMETHYL SULFOXIDE, GLYCEROL, ... | Authors: | Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G, Patel, J, Greenwood, R. | Deposit date: | 2012-02-16 | Release date: | 2012-03-21 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation J.Med.Chem., 55, 2012
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4K7G
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![BU of 4k7g by Molmil](/molmil-images/mine/4k7g) | Crystal structure of a 3-hydroxyproline dehydratse from agrobacterium vitis, target efi-506470, with bound pyrrole 2-carboxylate, ordered active site | Descriptor: | 3-hydroxyproline dehydratse, ACETATE ION, CITRIC ACID, ... | Authors: | Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | Deposit date: | 2013-04-17 | Release date: | 2013-05-01 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure of a 3-hydroxyproline dehydratse from agrobacterium vitis, target efi-506470, with bound pyrrole 2-carboxylate, ordered active site To be Published
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1AO3
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3LKD
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![BU of 3lkd by Molmil](/molmil-images/mine/3lkd) | Crystal Structure of the type I restriction-modification system methyltransferase subunit from Streptococcus thermophilus, Northeast Structural Genomics Consortium Target SuR80 | Descriptor: | Type I restriction-modification system methyltransferase subunit | Authors: | Vorobiev, S, Su, M, Seetharaman, J, Mao, M, Xiao, R, Foote, E.L, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-01-27 | Release date: | 2010-02-09 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Northeast Structural Genomics Consortium Target SuR80 To be published
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4O1K
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![BU of 4o1k by Molmil](/molmil-images/mine/4o1k) | Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. | Descriptor: | Carbonic anhydrase, ZINC ION | Authors: | Lehneck, R, Neumann, P, Vullo, D, Elleuche, S, Supuran, C.T, Ficner, R, Poggeler, S. | Deposit date: | 2013-12-16 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Crystal structures of two tetrameric beta-carbonic anhydrases from the filamentous ascomycete Sordaria macrospora. Febs J., 281, 2014
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1PZX
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![BU of 1pzx by Molmil](/molmil-images/mine/1pzx) | Hypothetical protein APC36103 from Bacillus stearothermophilus: a lipid binding protein | Descriptor: | Hypothetical protein APC36103, PALMITIC ACID | Authors: | Zhang, R, Osipiuk, J, Zhou, M, Alkire, R, Moy, S, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2003-07-14 | Release date: | 2004-01-20 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Lipid binding protein APC36103 from Bacillus Stearothermophilus To be Published
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1HHN
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![BU of 1hhn by Molmil](/molmil-images/mine/1hhn) | Calreticulin P-domain | Descriptor: | CALRETICULIN | Authors: | Ellgaard, L, Riek, R, Herrmann, T, Guntert, P, Braun, D, Helenius, A, Wuthrich, K. | Deposit date: | 2000-12-22 | Release date: | 2001-03-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR Structure of the Calreticulin P-Domain Proc.Natl.Acad.Sci.USA, 98, 2001
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1PIS
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![BU of 1pis by Molmil](/molmil-images/mine/1pis) | SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. | Deposit date: | 1994-12-22 | Release date: | 1995-06-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine pancreatic phospholipase A2. EMBO J., 14, 1995
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1PIR
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![BU of 1pir by Molmil](/molmil-images/mine/1pir) | SOLUTION STRUCTURE OF PORCINE PANCREATIC PHOSPHOLIPASE A2 | Descriptor: | CALCIUM ION, PHOSPHOLIPASE A2 | Authors: | Van Den Berg, B.D, Tessari, M, De Haas, G.H, Verheij, H.M, Boelens, R, Kaptein, R. | Deposit date: | 1994-12-22 | Release date: | 1995-06-03 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of porcine pancreatic phospholipase A2. EMBO J., 14, 1995
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1H52
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![BU of 1h52 by Molmil](/molmil-images/mine/1h52) | Binding of Phosphate and Pyrophosphate ions at the active site of human Angiogenin as revealed by X-ray Crystallography | Descriptor: | ANGIOGENIN, PYROPHOSPHATE 2- | Authors: | Leonidas, D.D, Chavali, G.B, Jardine, A.M, Li, S, Shapiro, R, Acharya, K.R. | Deposit date: | 2001-05-18 | Release date: | 2001-08-09 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography Protein Sci., 10, 2001
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1POV
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5L9V
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