8CGX
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![BU of 8cgx by Molmil](/molmil-images/mine/8cgx) | structure of HEX-1 from N. crassa crystallized in cellulo, diffracted at 100K and resolved using XDS | 分子名称: | Woronin body major protein | 著者 | Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L. | 登録日 | 2023-02-06 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
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8CD5
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![BU of 8cd5 by Molmil](/molmil-images/mine/8cd5) | structure of HEX-1 from N. crassa crystallized in cellulo, diffracted at 100K and resolved using CrystFEL | 分子名称: | Woronin body major protein | 著者 | Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L. | 登録日 | 2023-01-30 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
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5ZWN
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![BU of 5zwn by Molmil](/molmil-images/mine/5zwn) | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.3 angstrom (Part II: U1 snRNP region) | 分子名称: | 56 kDa U1 small nuclear ribonucleoprotein component, Pre-mRNA-processing factor 39, Pre-mRNA-splicing ATP-dependent RNA helicase PRP28, ... | 著者 | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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5ZWM
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![BU of 5zwm by Molmil](/molmil-images/mine/5zwm) | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... | 著者 | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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6OBU
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![BU of 6obu by Molmil](/molmil-images/mine/6obu) | PP1 Y134K in complex with Microcystin LR | 分子名称: | CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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7RUD
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![BU of 7rud by Molmil](/molmil-images/mine/7rud) | DAHP synthase complex with trifluoropyruvate oxime | 分子名称: | (2Z)-3,3,3-trifluoro-2-(hydroxyimino)propanoic acid, Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive | 著者 | Heimhalt, M, Mukherjee, P, Grainger, R, Szabla, R, Brown, C, Turner, R, Junop, M.S, Berti, P.J. | 登録日 | 2021-08-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. Acs Infect Dis., 7, 2021
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7RUE
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![BU of 7rue by Molmil](/molmil-images/mine/7rue) | DAHP synthase complexed with trifluoropyruvate semicarbazone | 分子名称: | (2E)-2-(2-carbamoylhydrazinylidene)-3,3,3-trifluoropropanoic acid, MANGANESE (II) ION, Phospho-2-dehydro-3-deoxyheptonate aldolase, ... | 著者 | Heimhalt, M, Mukherjee, P, Grainger, R, Szabla, R, Brown, C, Turner, R, Junop, M.S, Berti, P.J. | 登録日 | 2021-08-16 | 公開日 | 2021-11-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. Acs Infect Dis., 7, 2021
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6OBN
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![BU of 6obn by Molmil](/molmil-images/mine/6obn) | The crystal structure of coexpressed SDS22:PP1 complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FE (III) ION, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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6RJ1
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![BU of 6rj1 by Molmil](/molmil-images/mine/6rj1) | |
8C83
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![BU of 8c83 by Molmil](/molmil-images/mine/8c83) | Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-18 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8CAH
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![BU of 8cah by Molmil](/molmil-images/mine/8cah) | Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8CAS
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![BU of 8cas by Molmil](/molmil-images/mine/8cas) | Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8CBJ
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![BU of 8cbj by Molmil](/molmil-images/mine/8cbj) | Cryo-EM structure of Otu2-bound cytoplasmic pre-40S ribosome biogenesis complex | 分子名称: | 20S pre-ribosomal RNA, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-25 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8LPR
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6OBR
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![BU of 6obr by Molmil](/molmil-images/mine/6obr) | PP1 Y134A in complex with Microcystin LR | 分子名称: | CHLORIDE ION, MANGANESE (II) ION, Microcystin LR, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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1BHY
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![BU of 1bhy by Molmil](/molmil-images/mine/1bhy) | LOW TEMPERATURE MIDDLE RESOLUTION STRUCTURE OF P64K FROM MASC DATA | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, P64K | 著者 | Ramin, M, Shepard, W, Fourme, R, Kahn, R. | 登録日 | 1998-06-10 | 公開日 | 1998-11-04 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (4.18 Å) | 主引用文献 | Multiwavelength anomalous solvent contrast (MASC): derivation of envelope structure-factor amplitudes and comparison with model values. Acta Crystallogr.,Sect.D, 55, 1999
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6OBS
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![BU of 6obs by Molmil](/molmil-images/mine/6obs) | PP1 Y134K | 分子名称: | GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... | 著者 | Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. | 登録日 | 2019-03-21 | 公開日 | 2019-09-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.803 Å) | 主引用文献 | SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
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6AL1
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![BU of 6al1 by Molmil](/molmil-images/mine/6al1) | The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 181 and 184 | 分子名称: | Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... | 著者 | Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. | 登録日 | 2018-09-05 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
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5LNF
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![BU of 5lnf by Molmil](/molmil-images/mine/5lnf) | Solution NMR structure of farnesylated PEX19, C-terminal domain | 分子名称: | FARNESYL, Peroxisomal biogenesis factor 19 | 著者 | Emmanouilidis, L, Schuetz, U, Tripsianes, K, Madl, T, Radke, J, Rucktaeschel, R, Wilmanns, M, Schliebs, W, Erdmann, R, Sattler, M. | 登録日 | 2016-08-04 | 公開日 | 2017-03-15 | 最終更新日 | 2019-09-11 | 実験手法 | SOLUTION NMR | 主引用文献 | Allosteric modulation of peroxisomal membrane protein recognition by farnesylation of the peroxisomal import receptor PEX19. Nat Commun, 8, 2017
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6Y53
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![BU of 6y53 by Molmil](/molmil-images/mine/6y53) | human 17S U2 snRNP low resolution part | 分子名称: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | 著者 | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | 登録日 | 2020-02-24 | 公開日 | 2020-06-17 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | 主引用文献 | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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6Y9S
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![BU of 6y9s by Molmil](/molmil-images/mine/6y9s) | Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16 | 分子名称: | ACETATE ION, Glycogen synthase kinase-3 beta, ~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide | 著者 | Krapp, S, Griessner, A, Blaesse, M, Buonfiglio, R, Ombrato, R. | 登録日 | 2020-03-10 | 公開日 | 2020-05-20 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Discovery of Novel Imidazopyridine GSK-3 beta Inhibitors Supported by Computational Approaches. Molecules, 25, 2020
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6Y6X
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![BU of 6y6x by Molmil](/molmil-images/mine/6y6x) | Tetracenomycin X bound to the human ribosome | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Buschauer, R, Cheng, J, Berninghausen, O, Beckmann, R, Wilson, D.N. | 登録日 | 2020-02-27 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel. Nat.Chem.Biol., 16, 2020
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6YCB
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![BU of 6ycb by Molmil](/molmil-images/mine/6ycb) | Structure the ananain protease from Ananas comosus covalently bound to with the E64 inhibitor | 分子名称: | Ananain, GLYCEROL, L(+)-TARTARIC ACID, ... | 著者 | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | 登録日 | 2020-03-18 | 公開日 | 2020-11-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.257 Å) | 主引用文献 | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10, 2020
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6AKQ
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![BU of 6akq by Molmil](/molmil-images/mine/6akq) | The PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 263 and 267 | 分子名称: | PDZ tandem fragment of A. aeolicus site-2 protease homolog with the PA tag insertion | 著者 | Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. | 登録日 | 2018-09-03 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
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6AL0
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![BU of 6al0 by Molmil](/molmil-images/mine/6al0) | The NZ-1 Fab complexed with the PDZ tandem fragment of A. aeolicus S2P homolog with the PA12 tag inserted between the residues 263 and 267 | 分子名称: | Heavy chain of antigen binding fragment, Fab of NZ-1, Light chain of antigen binding fragment, ... | 著者 | Tamura, R, Oi, R, Kaneko, M.K, Kato, Y, Nogi, T. | 登録日 | 2018-09-05 | 公開日 | 2019-02-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Application of the NZ-1 Fab as a crystallization chaperone for PA tag-inserted target proteins. Protein Sci., 28, 2019
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