6Y9S

Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16

Summary for 6Y9S

Entry DOI	10.2210/pdb6y9s/pdb
Descriptor	Glycogen synthase kinase-3 beta, ~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide, ACETATE ION, ... (4 entities in total)
Functional Keywords	glycogen synthase kinase-3 beta, indazole, inhibitor, kinase, transferase, proteros biostructures gmbh
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	80731.61
Authors	Krapp, S.,Griessner, A.,Blaesse, M.,Buonfiglio, R.,Ombrato, R. (deposition date: 2020-03-10, release date: 2020-05-20)
Primary citation	Buonfiglio, R.,Prati, F.,Bischetti, M.,Cavarischia, C.,Furlotti, G.,Ombrato, R. Discovery of Novel Imidazopyridine GSK-3 beta Inhibitors Supported by Computational Approaches. Molecules, 25:-, 2020 Cited by PubMed: 32380735 DOI: 10.3390/molecules25092163 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.03 Å)

Structure validation