6Y9S

Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Glycogen synthase kinase-3 beta	polymer	350	39882.8	2	UniProt (P49841) Pfam (PF00069)	Homo sapiens (Human)	GSK-3 beta,Serine/threonine-protein kinase GSK3B
2	C, F (A, B)	~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide	non-polymer		394.5	2	Chemie (OHK)
3	D, E, G (A, B)	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
4	H, I (A, B)	water	water		18.0	282	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	79765.5
Non-Polymers*	Number of molecules	5
	Total formula weight	966.1
All*	Total formula weight	80731.6

*Water molecules are not included.