6Y9S
Crystal structure of GSK-3b in complex with the imidazo[1,5-a]pyridine-3-carboxamide inhibitor 16
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Glycogen synthase kinase-3 beta | polymer | 350 | 39882.8 | 2 | UniProt (P49841) Pfam (PF00069) In PDB | Homo sapiens (Human) | GSK-3 beta,Serine/threonine-protein kinase GSK3B |
| 2 | A, B | ~{N}-(oxan-4-ylmethyl)-6-(5-propan-2-yloxypyridin-3-yl)imidazo[1,5-a]pyridine-3-carboxamide | non-polymer | 394.5 | 2 | Chemie (OHK) | |||
| 3 | A, B | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
| 4 | water | water | 18.0 | 282 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79765.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 966.1 | |
| All* | Total formula weight | 80731.6 |
