7CKL
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![BU of 7ckl by Molmil](/molmil-images/mine/7ckl) | Structure of Lassa virus polymerase bound to Z matrix protein | 分子名称: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | 登録日 | 2020-07-17 | 公開日 | 2021-05-05 | 最終更新日 | 2021-11-17 | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals Nat Microbiol, 6, 2021
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2XY3
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![BU of 2xy3 by Molmil](/molmil-images/mine/2xy3) | Structure of the Bacillus subtilis prophage dUTPase with dUpNHpp | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, SPBC2 PROPHAGE-DERIVED DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE YOSS | 著者 | Garcia-Nafria, J, Harkiolaki, M, Persson, R, Fogg, M.J, Wilson, K.S. | 登録日 | 2010-11-12 | 公開日 | 2011-02-23 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The Structure of Bacillus Subtilis Sp Beta Prophage Dutpase and its Complexes with Two Nucleotides Acta Crystallogr.,Sect.D, 67, 2011
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2XLT
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![BU of 2xlt by Molmil](/molmil-images/mine/2xlt) | Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: complex with 3-Acetylpyridine adenine dinucleotide phosphate (APADP) | 分子名称: | 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... | 著者 | Orru, R, Fraaije, M.W, Mattevi, A. | 登録日 | 2010-07-21 | 公開日 | 2010-09-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase. J. Biol. Chem., 285, 2010
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7CHO
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![BU of 7cho by Molmil](/molmil-images/mine/7cho) | Crystal structure of SARS-CoV-2 antibody P5A-1D2 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-1D2 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | 登録日 | 2020-07-06 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.561 Å) | 主引用文献 | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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2XOD
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![BU of 2xod by Molmil](/molmil-images/mine/2xod) | Crystal structure of flavoprotein NrdI from Bacillus anthracis in the oxidised form | 分子名称: | CACODYLATE ION, FLAVIN MONONUCLEOTIDE, NRDI PROTEIN, ... | 著者 | Johansson, R, Sprenger, J, Torrents, E, Sahlin, M, Sjoberg, B.M, Logan, D.T. | 登録日 | 2010-08-14 | 公開日 | 2010-08-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | High Resolution Crystal Structures of Nrdi in the Oxidised and Reduced States: An Unusual Flavodoxin FEBS J., 277, 2010
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2XK6
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![BU of 2xk6 by Molmil](/molmil-images/mine/2xk6) | Structure of Nek2 bound to aminopyrazine compound 36 | 分子名称: | CHLORIDE ION, SERINE/THREONINE-PROTEIN KINASE NEK2, cis-4-[3-amino-6-(3-cyclopropylthiophen-2-yl)pyrazin-2-yl]cyclohexanecarboxylic acid | 著者 | Mas-Droux, C, Bayliss, R. | 登録日 | 2010-07-07 | 公開日 | 2010-10-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: Sar and Structural Characterization. J.Med.Chem., 53, 2010
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2XOY
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2KW5
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![BU of 2kw5 by Molmil](/molmil-images/mine/2kw5) | Solution NMR Structure of the Slr1183 protein from Synechocystis sp. PCC 6803, Northeast Structural Genomics Consortium Target SgR145 | 分子名称: | Slr1183 protein | 著者 | Rossi, P, Forouhar, F, Lee, H, Lange, O, Mao, B, Lemak, A, Maglaqui, M, Belote, R, Ciccosanti, C, Foote, E, Sahdev, S, Acton, T, Xiao, R, Everett, J, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-03-31 | 公開日 | 2010-04-21 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples. Proc.Natl.Acad.Sci.USA, 109, 2012
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7CHS
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![BU of 7chs by Molmil](/molmil-images/mine/7chs) | Crystal structure of SARS-CoV-2 antibody P22A-1D1 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P22A-1D1 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | 登録日 | 2020-07-06 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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2XNE
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![BU of 2xne by Molmil](/molmil-images/mine/2xne) | Structure of Aurora-A bound to an imidazopyrazine inhibitor | 分子名称: | 3-chloro-N-(4-morpholin-4-ylphenyl)-6-pyridin-3-ylimidazo[1,2-a]pyrazin-8-amine, SERINE/THREONINE-PROTEIN KINASE 6 | 著者 | Kosmopoulou, M, Bayliss, R. | 登録日 | 2010-08-02 | 公開日 | 2010-09-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-based design of imidazo[1,2-a]pyrazine derivatives as selective inhibitors of Aurora-A kinase in cells. Bioorg. Med. Chem. Lett., 20, 2010
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2XZ6
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![BU of 2xz6 by Molmil](/molmil-images/mine/2xz6) | MTSET-modified Y53C mutant of Aplysia AChBP | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, SOLUBLE ACETYLCHOLINE RECEPTOR | 著者 | Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, Van Elk, R, Van Der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C. | 登録日 | 2010-11-23 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.137 Å) | 主引用文献 | Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein J.Biol.Chem., 286, 2011
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2XOZ
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![BU of 2xoz by Molmil](/molmil-images/mine/2xoz) | C-terminal cysteine rich domain of human CHFR bound to AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, E3 UBIQUITIN-PROTEIN LIGASE CHFR, ZINC ION | 著者 | Oberoi, J, Bayliss, R. | 登録日 | 2010-08-24 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.374 Å) | 主引用文献 | Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr). J.Biol.Chem., 285, 2010
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7C3T
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![BU of 7c3t by Molmil](/molmil-images/mine/7c3t) | Crystal structure of NE0047 (N66Q) mutant in complex with 8-azaguanine | 分子名称: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION | 著者 | Gaded, V, Bitra, A, Singh, J, Anand, R. | 登録日 | 2020-05-14 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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7CHP
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![BU of 7chp by Molmil](/molmil-images/mine/7chp) | Crystal structure of SARS-CoV-2 antibody P5A-3C8 with RBD | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, antibody P5A-3C8 heavy chain, ... | 著者 | Wang, X, Zhang, L, Ge, J, Wang, R, Zhang, Q. | 登録日 | 2020-07-06 | 公開日 | 2021-05-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.357 Å) | 主引用文献 | Potent and protective IGHV3-53/3-66 public antibodies and their shared escape mutant on the spike of SARS-CoV-2. Nat Commun, 12, 2021
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2Y0R
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![BU of 2y0r by Molmil](/molmil-images/mine/2y0r) | Structural basis for the allosteric interference of myosin function by mutants G680A and G680V of Dictyostelium myosin-2 | 分子名称: | MYOSIN-2 HEAVY CHAIN | 著者 | Preller, M, Bauer, S, Adamek, N, Fujita-Becker, S, Fedorov, R, Geeves, M.A, Manstein, D.J. | 登録日 | 2010-12-07 | 公開日 | 2011-07-20 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V. J.Biol.Chem., 286, 2011
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7CWH
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![BU of 7cwh by Molmil](/molmil-images/mine/7cwh) | Structural basis of RACK7 PHD to read a pediatric glioblastoma-associated histone mutation H3.3G34R | 分子名称: | Peptide from Histone H3.3, Protein kinase C-binding protein 1, ZINC ION | 著者 | Lan, W.X, Li, Z, Jiao, F.F, Wang, C.X, Guo, R, Cao, C.Y. | 登録日 | 2020-08-28 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis of RACK7 PHD domain to read a pediatric glioblastoma‐associated histone mutation H3.3G34R Chin.J.Chem., 2021
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2XXQ
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![BU of 2xxq by Molmil](/molmil-images/mine/2xxq) | A widespread family of bacterial cell wall assembly proteins | 分子名称: | (2Z,6Z,10Z,14Z,18Z,22Z,26Z)-3,7,11,15,19,23,27,31-octamethyldotriaconta-2,6,10,14,18,22,26,30-octaen-1-yl trihydrogen diphosphate, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Marles-Wright, J, Kawai, Y, Emmins, R, Ishikawa, S, Kuwano, M, Heinz, N, Cleverley, R.M, Bui, N.K, Ogasawara, N, Lewis, R.J, Vollmer, W, Daniel, R.A, Errington, J. | 登録日 | 2010-11-11 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | A Widespread Family of Bacterial Cell Wall Assembly Proteins. Embo J., 30, 2011
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7C3U
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![BU of 7c3u by Molmil](/molmil-images/mine/7c3u) | Crystal structure of NE0047 (N66A) mutant in complex with 8-azaguanine | 分子名称: | 1,2-ETHANEDIOL, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | 著者 | Gaded, V, Bitra, A, Singh, J, Anand, R. | 登録日 | 2020-05-14 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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2V5X
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![BU of 2v5x by Molmil](/molmil-images/mine/2v5x) | Crystal structure of HDAC8-inhibitor complex | 分子名称: | (2R)-N~8~-HYDROXY-2-{[(5-METHOXY-2-METHYL-1H-INDOL-3-YL)ACETYL]AMINO}-N~1~-[2-(2-PHENYL-1H-INDOL-3-YL)ETHYL]OCTANEDIAMIDE, HISTONE DEACETYLASE 8, POTASSIUM ION, ... | 著者 | Di Marco, S, Vannini, A, Volpari, C, Gallinari, P, Jones, P, Mattu, M, Carfi, A, Defrancesco, R, Steinkuhler, C. | 登録日 | 2007-07-10 | 公開日 | 2007-09-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Substrate Binding to Histone Deacetylases as Revealed by Crystal Structure of Hdac8-Substrate Complex Embo Rep., 8, 2007
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1CL1
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7C3S
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![BU of 7c3s by Molmil](/molmil-images/mine/7c3s) | Crystal structure of NE0047 (E143D) mutant in complex with 8-azaguanine | 分子名称: | 1,2-ETHANEDIOL, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | 著者 | Gaded, V, Bitra, A, Singh, J, Anand, R. | 登録日 | 2020-05-14 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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7C6Q
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![BU of 7c6q by Molmil](/molmil-images/mine/7c6q) | Novel natural PPARalpha agonist with a unique binding mode | 分子名称: | 13-methyl[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridin-13-ium, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, Peroxisome proliferator-activated receptor alpha | 著者 | Tian, S.Y, Wang, R, Zheng, W.L, Li, Y. | 登録日 | 2020-05-22 | 公開日 | 2021-05-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural Basis for PPARs Activation by The Dual PPAR alpha / gamma Agonist Sanguinarine: A Unique Mode of Ligand Recognition. Molecules, 26, 2021
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7CPH
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2VI6
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![BU of 2vi6 by Molmil](/molmil-images/mine/2vi6) | Crystal Structure of the Nanog Homeodomain | 分子名称: | HOMEOBOX PROTEIN NANOG | 著者 | Jauch, R, Ng, C.K.L, Saitakendu, K.S, Stevens, R.C, Kolatkar, P.R. | 登録日 | 2007-11-28 | 公開日 | 2008-01-15 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal Structure and DNA Binding of the Homeodomain of the Stem Cell Transcription Factor Nanog. J.Mol.Biol., 376, 2008
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7YLZ
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![BU of 7ylz by Molmil](/molmil-images/mine/7ylz) | |