7C3U

Crystal structure of NE0047 (N66A) mutant in complex with 8-azaguanine

Summary for 7C3U

• Entry DOI: 10.2210/pdb7c3u/pdb
• Descriptor: Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, ... (5 entities in total)
• Functional Keywords: hydrolase, deaminase, 8-azaguanine, complex
• Biological source: Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
• Total number of polymer chains: 2
• Total formula weight: 40905.33

Authors

Gaded, V.,Bitra, A.,Singh, J.,Anand, R. (deposition date: 2020-05-14, release date: 2021-05-26, Last modification date: 2023-11-29)

• Primary citation: Singh, J.,Gaded, V.,Bitra, A.,Anand, R.; Structure guided mutagenesis reveals the substrate determinants of guanine deaminase.; J.Struct.Biol., 213:107747-107747, 2021; PubMed: 34010666; DOI: 10.1016/j.jsb.2021.107747

Experimental method

X-RAY DIFFRACTION (1.86 Å)