7C3U
Crystal structure of NE0047 (N66A) mutant in complex with 8-azaguanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cytidine and deoxycytidylate deaminase zinc-binding region | polymer | 193 | 20204.1 | 2 | UniProt (Q82Y41) Pfam (PF00383) | Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298) | Guanine deaminase |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL | non-polymer | 152.1 | 2 | Chemie (AZG) | |||
| 4 | G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 91 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 193 (UniProt: Q82Y41)
| PDB | External Database | Details |
|---|---|---|
| Ala 66 | Asn 66 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 40408.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 497.1 | |
| All* | Total formula weight | 40905.3 |
