2XCU
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![BU of 2xcu by Molmil](/molmil-images/mine/2xcu) | Membrane-embedded monofunctional glycosyltransferase WaaA of Aquifex aeolicus, complex with CMP | 分子名称: | 3-DEOXY-D-MANNO-2-OCTULOSONIC ACID TRANSFERASE, BETA-MERCAPTOETHANOL, CHLORIDE ION, ... | 著者 | Schmidt, H, Hansen, G, Hilgenfeld, R, Mamat, U, Mesters, J.R. | 登録日 | 2010-04-26 | 公開日 | 2011-05-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural and Mechanistic Analysis of the Membrane-Embedded Glycosyltransferase Waaa Required for Lipopolysaccharide Synthesis. Proc.Natl.Acad.Sci.USA, 109, 2012
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5KZE
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![BU of 5kze by Molmil](/molmil-images/mine/5kze) | N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus | 分子名称: | GLYCEROL, N-acetylneuraminate lyase, SULFATE ION | 著者 | North, R.A, Watson, A.J.A, Pearce, F.G, Muscroft-Taylor, A.C, Friemann, R, Fairbanks, A.J, Dobson, R.C.J. | 登録日 | 2016-07-25 | 公開日 | 2017-01-11 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus. FEBS Lett., 590, 2016
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6W6P
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5I7O
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![BU of 5i7o by Molmil](/molmil-images/mine/5i7o) | |
6W02
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![BU of 6w02 by Molmil](/molmil-images/mine/6w02) | Crystal Structure of ADP ribose phosphatase of NSP3 from SARS CoV-2 in the complex with ADP ribose | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5-DIPHOSPHORIBOSE, Non-structural protein 3 | 著者 | Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-02-28 | 公開日 | 2020-03-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
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5IAY
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![BU of 5iay by Molmil](/molmil-images/mine/5iay) | NMR structure of UHRF1 Tandem Tudor Domains in a complex with Spacer peptide | 分子名称: | E3 ubiquitin-protein ligase UHRF1, Spacer | 著者 | Fang, J, Cheng, J, Wang, J, Zhang, Q, Liu, M, Gong, R, Wang, P, Zhang, X, Feng, Y, Lan, W, Gong, Z, Tang, C, Wong, J, Yang, H, Cao, C, Xu, Y. | 登録日 | 2016-02-22 | 公開日 | 2016-04-20 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition Nat Commun, 7, 2016
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5ICE
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![BU of 5ice by Molmil](/molmil-images/mine/5ice) | Crystal structure of (S)-norcoclaurine 6-O-methyltransferase with S-adenosyl-L-homocysteine and norlaudanosoline | 分子名称: | (1S)-1-(3,4-dihydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol, (S)-norcoclaurine 6-O-methyltransferase, 1,2-ETHANEDIOL, ... | 著者 | Robin, A.Y, Graindorge, M, Giustini, C, Dumas, R, Matringe, M. | 登録日 | 2016-02-23 | 公開日 | 2016-06-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of norcoclaurine-6-O-methyltransferase, a key rate-limiting step in the synthesis of benzylisoquinoline alkaloids. Plant J., 87, 2016
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3PS4
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![BU of 3ps4 by Molmil](/molmil-images/mine/3ps4) | PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Microtubule-associated serine/threonine-protein kinase 1 | 著者 | Ugochukwu, E, Wang, J, Krojer, T, Muniz, J.R.C, Sethi, R, Pike, A.C.W, Roos, A, Salah, E, Cocking, R, Savitsky, P, Doyle, D.A, von Delft, F, Bountra, C, Arrowsmith, C.H, Weigelt, J, Edwards, A, Knapp, S, Elkins, J.M, Structural Genomics Consortium (SGC) | 登録日 | 2010-11-30 | 公開日 | 2010-12-29 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | PDZ domain from Human microtubule-associated serine/threonine-protein kinase 1 TO BE PUBLISHED
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3PWD
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![BU of 3pwd by Molmil](/molmil-images/mine/3pwd) | Crystal structure of maize CK2 in complex with NBC (Z1) | 分子名称: | 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one, Casein kinase II subunit alpha | 著者 | Battistutta, R, Mazzorana, M. | 登録日 | 2010-12-08 | 公開日 | 2011-11-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A Cell.Mol.Life Sci., 69, 2012
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3PUT
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![BU of 3put by Molmil](/molmil-images/mine/3put) | Crystal Structure of the CERT START domain (mutant V151E) from Rhizobium etli at the resolution 1.8A, Northeast Structural Genomics Consortium Target ReR239. | 分子名称: | HEXANE-1,6-DIOL, Hypothetical conserved protein | 著者 | Kuzin, A, Chen, Y, Seetharaman, J, Mao, M, Xiao, R, Ciccosanti, C, Wang, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Tong, L, Hunt, J.F, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-12-06 | 公開日 | 2010-12-22 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.828 Å) | 主引用文献 | Crystal Structure of the CERT START domain (mutant V151E) from Rhizobium etli at the resolution 1.8A, Northeast Structural Genomics Consortium Target ReR239. To be Published
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5IMH
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5IN3
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![BU of 5in3 by Molmil](/molmil-images/mine/5in3) | Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase | 分子名称: | 1,2-ETHANEDIOL, 1-O-phosphono-alpha-D-glucopyranose, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, ... | 著者 | Kopec, J, McCorvie, T, Tallant, C, Velupillai, S, Shrestha, L, Fitzpatrick, F, Patel, D, Chalk, R, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W. | 登録日 | 2016-03-07 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase. Hum.Mol.Genet., 25, 2016
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5INH
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![BU of 5inh by Molmil](/molmil-images/mine/5inh) | Crystal structure of Autotaxin/ENPP2 with a covalent fragment | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Klein, M.G, Tjhen, R. | 登録日 | 2016-03-07 | 公開日 | 2017-03-15 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes. J. Med. Chem., 60, 2017
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1T8O
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![BU of 1t8o by Molmil](/molmil-images/mine/1t8o) | CRYSTAL STRUCTURE OF THE P1 TRP BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX | 分子名称: | Chymotrypsin A, Pancreatic trypsin inhibitor, SULFATE ION | 著者 | Czapinska, H, Helland, R, Otlewski, J, Smalas, A.O. | 登録日 | 2004-05-13 | 公開日 | 2005-03-08 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of five bovine chymotrypsin complexes with P1 BPTI variants. J.Mol.Biol., 344, 2004
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5IMQ
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![BU of 5imq by Molmil](/molmil-images/mine/5imq) | Structure of ribosome bound to cofactor at 3.8 angstrom resolution | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Kumar, V, Ero, R, Jian, G.K, Ahmed, T, Zhan, Y, Bhushan, S, Gao, Y.G. | 登録日 | 2016-03-06 | 公開日 | 2016-05-18 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome J.Biol.Chem., 291, 2016
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5IQX
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![BU of 5iqx by Molmil](/molmil-images/mine/5iqx) | 1.05A resolution structure of Holo HasAp (R33A) from Pseudomonas aeruginosa | 分子名称: | D-MALATE, Heme acquisition protein HasAp, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Kumar, R, Lovell, S, Battaile, K.P, Yao, H, Rivera, M. | 登録日 | 2016-03-11 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Replacing Arginine 33 for Alanine in the Hemophore HasA from Pseudomonas aeruginosa Causes Closure of the H32 Loop in the Apo-Protein. Biochemistry, 55, 2016
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1CWQ
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![BU of 1cwq by Molmil](/molmil-images/mine/1cwq) | M INTERMEDIATE STRUCTURE OF THE WILD TYPE BACTERIORHODOPSIN IN COMBINATION WITH THE GROUND STATE STRUCTURE | 分子名称: | BACTERIORHODOPSIN ("M" STATE INTERMEDIATE IN COMBINATION WITH GROUND STATE), HEXANE, N-OCTANE, ... | 著者 | Sass, H.J, Berendzen, J, Neff, D, Gessenich, R, Ormos, P, Bueldt, G. | 登録日 | 1999-08-26 | 公開日 | 1999-10-20 | 最終更新日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural alterations for proton translocation in the M state of wild-type bacteriorhodopsin. Nature, 406, 2000
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5IRA
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![BU of 5ira by Molmil](/molmil-images/mine/5ira) | Expanding Nature's Catalytic Repertoire -Directed Evolution of an Artificial Metalloenzyme for In Vivo Metathesis | 分子名称: | Artificial Metathesase, [1-[4-[[5-[(3~{a}~{S},4~{S},6~{a}~{R})-2-oxidanylidene-1,3,3~{a},4,6,6~{a}-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]methyl]-2,6-dimethyl-phenyl]-3-(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-1-ium-2-yl]-bis(chloranyl)ruthenium | 著者 | Heinisch, T, Jeschek, M, Reuter, R, Trindler, C, Panke, S, Ward, T.R. | 登録日 | 2016-03-12 | 公開日 | 2016-08-31 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Directed evolution of artificial metalloenzymes for in vivo metathesis. Nature, 537, 2016
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5IQO
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![BU of 5iqo by Molmil](/molmil-images/mine/5iqo) | Crystal structure of the E. coli type 1 pilus subunit FimG (engineered variant with substitutions Q134E and S138E; N-terminal FimG residues 1-12 truncated) in complex with the donor strand peptide DsF_T4R-T6R-D13N | 分子名称: | 1,2-ETHANEDIOL, COBALT (II) ION, PENTAETHYLENE GLYCOL, ... | 著者 | Giese, C, Eras, J, Kern, A, Capitani, G, Glockshuber, R. | 登録日 | 2016-03-11 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | 主引用文献 | Accelerating the Association of the Most Stable Protein-Ligand Complex by More than Two Orders of Magnitude. Angew.Chem.Int.Ed.Engl., 55, 2016
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6VTX
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![BU of 6vtx by Molmil](/molmil-images/mine/6vtx) | Crystal structure of human KLF4 zinc finger DNA binding domain in complex with NANOG DNA | 分子名称: | DNA (5'-D(*AP*GP*GP*GP*GP*GP*TP*GP*TP*GP*CP*C)-3'), DNA (5'-D(*GP*GP*CP*AP*CP*AP*CP*CP*CP*CP*CP*T)-3'), Krueppel-like factor 4, ... | 著者 | Sharma, R, Sharma, S, Choi, K.J, Ferreon, A.C.M, Ferreon, J.C, Sankaran, B, MacKenzie, K.R, Kim, C. | 登録日 | 2020-02-13 | 公開日 | 2021-09-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Liquid condensation of reprogramming factor KLF4 with DNA provides a mechanism for chromatin organization. Nat Commun, 12, 2021
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5IQW
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![BU of 5iqw by Molmil](/molmil-images/mine/5iqw) | 1.95A resolution structure of Apo HasAp (R33A) from Pseudomonas aeruginosa | 分子名称: | ACETATE ION, CADMIUM ION, Heme acquisition protein HasAp | 著者 | Kumar, R, Lovell, S, Battaile, K.P, Yao, H, Rivera, M. | 登録日 | 2016-03-11 | 公開日 | 2016-04-20 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Replacing Arginine 33 for Alanine in the Hemophore HasA from Pseudomonas aeruginosa Causes Closure of the H32 Loop in the Apo-Protein. Biochemistry, 55, 2016
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4KDZ
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6WCF
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![BU of 6wcf by Molmil](/molmil-images/mine/6wcf) | Crystal Structure of ADP ribose phosphatase of NSP3 from SARS-CoV-2 in complex with MES | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Non-structural protein 3 | 著者 | Michalska, K, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Mesecar, A, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-03-30 | 公開日 | 2020-04-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.065 Å) | 主引用文献 | Crystal structures of SARS-CoV-2 ADP-ribose phosphatase: from the apo form to ligand complexes. Iucrj, 7, 2020
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4KKN
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![BU of 4kkn by Molmil](/molmil-images/mine/4kkn) | Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704 | 分子名称: | Cytotoxic T-lymphocyte associated protein 4, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kumar, P.R, Ahmed, M, Banu, R, Bhosle, R, Bonanno, J, Calarese, D.A, Celikgil, A, Chamala, S, Chan, M.K, Chowdhury, S, Fiser, A, Garforth, S.J, Scott Glenn, A, Hammonds, J, Hillerich, B, Khafizov, K, Lafleur, J, Attonito, J, Love, J.D, Patel, H, Patel, R, Seidel, R.D, Smith, B, Stead, M, Toro, R, Casadevall, A, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | 登録日 | 2013-05-06 | 公開日 | 2013-06-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.253 Å) | 主引用文献 | Crystal structure of bovine CTLA-4, PSI-NYSGRC-012704 to be published
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1SUX
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![BU of 1sux by Molmil](/molmil-images/mine/1sux) | CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI AND 3-(2-benzothiazolylthio)-1-propanesulfonic acid | 分子名称: | 3-(2-BENZOTHIAZOLYLTHIO)-1-PROPANESULFONIC ACID, SULFATE ION, Triosephosphate isomerase, ... | 著者 | Tellez-Valencia, A, Olivares-Illana, V, Hernandez-Santoyo, A, Perez-Montfort, R, Costas, M, Rodriguez-Romero, A, Tuena De Gomez-Puyou, M, Gomez-Puyou, A. | 登録日 | 2004-03-26 | 公開日 | 2004-08-24 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface. J.Mol.Biol., 341, 2004
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