5IN3
Crystal structure of glucose-1-phosphate bound nucleotidylated human galactose-1-phosphate uridylyltransferase
Summary for 5IN3
Entry DOI | 10.2210/pdb5in3/pdb |
Descriptor | Galactose-1-phosphate uridylyltransferase, ZINC ION, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, ... (6 entities in total) |
Functional Keywords | galt, ump-galt, glucose-1-phosphate, galactose-1-phosphate uridylyltransferase, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 94994.99 |
Authors | Kopec, J.,McCorvie, T.,Tallant, C.,Velupillai, S.,Shrestha, L.,Fitzpatrick, F.,Patel, D.,Chalk, R.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.,Edwards, A.,Bountra, C.,Yue, W.W. (deposition date: 2016-03-07, release date: 2016-03-30, Last modification date: 2024-01-10) |
Primary citation | McCorvie, T.J.,Kopec, J.,Pey, A.L.,Fitzpatrick, F.,Patel, D.,Chalk, R.,Shrestha, L.,Yue, W.W. Molecular basis of classic galactosemia from the structure of human galactose 1-phosphate uridylyltransferase. Hum.Mol.Genet., 25:2234-2244, 2016 Cited by PubMed: 27005423DOI: 10.1093/hmg/ddw091 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.73 Å) |
Structure validation
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