3PWD
Crystal structure of maize CK2 in complex with NBC (Z1)
Summary for 3PWD
Entry DOI | 10.2210/pdb3pwd/pdb |
Descriptor | Casein kinase II subunit alpha, 8-hydroxy-4-methyl-9-nitro-2H-benzo[g]chromen-2-one (3 entities in total) |
Functional Keywords | protein kinase, inhibitor, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Zea mays (maize) |
Total number of polymer chains | 1 |
Total formula weight | 39562.39 |
Authors | Battistutta, R.,Mazzorana, M. (deposition date: 2010-12-08, release date: 2011-11-02, Last modification date: 2024-03-20) |
Primary citation | Sarno, S.,Mazzorana, M.,Traynor, R.,Ruzzene, M.,Cozza, G.,Pagano, M.A.,Meggio, F.,Zagotto, G.,Battistutta, R.,Pinna, L.A. Structural features underlying the selectivity of the kinase inhibitors NBC and dNBC: role of a nitro group that discriminates between CK2 and DYRK1A Cell.Mol.Life Sci., 69:449-460, 2012 Cited by PubMed: 21720886DOI: 10.1007/s00018-011-0758-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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