1SUX

CRYSTALLOGRAPHIC ANALYSIS OF THE COMPLEX BETWEEN TRIOSEPHOSPHATE ISOMERASE FROM TRYPANOSOMA CRUZI AND 3-(2-benzothiazolylthio)-1-propanesulfonic acid

Summary for 1SUX

DescriptorTriosephosphate isomerase, glycosomal, SULFATE ION, 3-(2-BENZOTHIAZOLYLTHIO)-1-PROPANESULFONIC ACID, ... (4 entities in total)
Functional Keywordstriosephosphate isomerase, trypanosoma cruzi, protein interfaces, benzothiazole inhibitor, isomerase
Biological sourceTrypanosoma cruzi
Cellular locationGlycosome P52270
Total number of polymer chains2
Total molecular weight55682.71
Authors
Tellez-Valencia, A.,Olivares-Illana, V.,Hernandez-Santoyo, A.,Perez-Montfort, R.,Costas, M.,Rodriguez-Romero, A.,Tuena De Gomez-Puyou, M.,Gomez-Puyou, A. (deposition date: 2004-03-26, release date: 2004-08-24, Last modification date: 2017-10-11)
Primary citation
Tellez-Valencia, A.,Olivares-Illana, V.,Hernandez-Santoyo, A.,Perez-Montfort, R.,Costas, M.,Rodriguez-Romero, A.,Lopez-Calahorra, F.,Tuena De Gomez-Puyou, M.,Gomez-Puyou, A.
Inactivation of triosephosphate isomerase from Trypanosoma cruzi by an agent that perturbs its dimer interface.
J.Mol.Biol., 341:1355-1365, 2004
PubMed: 15321726 (PDB entries with the same primary citation)
DOI: 10.1016/j.jmb.2004.06.056
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers701.0%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload