5EYT
 
 | | Crystal Structure of Adenylosuccinate Lyase from Schistosoma mansoni in complex with AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Adenylosuccinate lyase | | 著者 | Romanello, L, Torini, J.R, Bird, L, Nettleship, J, Owens, R, Reddivari, Y, Brandao-Neto, J, Pereira, H.M. | | 登録日 | 2015-11-25 | | 公開日 | 2016-11-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.3649 Å) | | 主引用文献 | Structural and kinetic analysis of Schistosoma mansoni Adenylosuccinate Lyase (SmADSL).
Mol. Biochem. Parasitol., 214, 2017
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8ORQ
 | | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase open clamp conformation | | 分子名称: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | | 登録日 | 2023-04-17 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
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8P2I
 | | Cryo-EM structure of Pyrococcus furiosus apo form RNA polymerase contracted clamp conformation with Spt4/5 | | 分子名称: | DNA-directed RNA polymerase subunit Rpo10, DNA-directed RNA polymerase subunit Rpo11, DNA-directed RNA polymerase subunit Rpo12, ... | | 著者 | Tarau, D.M, Reichelt, R, Heiss, F.B, Pilsl, M, Hausner, W, Engel, C, Grohmann, D. | | 登録日 | 2023-05-16 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis of archaeal RNA polymerase transcription elongation and Spt4/5 recruitment.
Nucleic Acids Res., 52, 2024
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3HZF
 | | Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group | | 分子名称: | Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid | | 著者 | Aparicio, R, Bleicher, L, Polikarpov, I. | | 登録日 | 2009-06-23 | | 公開日 | 2009-07-21 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.
Bmc Struct.Biol., 8, 2008
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1NXU
 | | CRYSTAL STRUCTURE OF E. COLI HYPOTHETICAL OXIDOREDUCTASE YIAK NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET ER82. | | 分子名称: | Hypothetical oxidoreductase yiaK, SULFATE ION | | 著者 | Forouhar, F, Lee, I, Benach, J, Kulkarni, K, Xiao, R, Acton, T.B, Shastry, R, Rost, B, Montelione, G.T, Tong, L, Northeast Structural Genomics Consortium (NESG) | | 登録日 | 2003-02-11 | | 公開日 | 2003-03-11 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-L-gulonate Reductase (YiaK).
J.Biol.Chem., 279, 2004
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1OB0
 | | Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface | | 分子名称: | ALPHA-AMYLASE, CALCIUM ION, SODIUM ION | | 著者 | Machius, M, Declerck, N, Huber, R, Wiegand, G. | | 登録日 | 2003-01-21 | | 公開日 | 2003-01-30 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Kinetic Stabilization of Bacillus Licheniformis Alpha-Amylase Through Introduction of Hydrophobic Residues at the Surface
J.Biol.Chem., 278, 2003
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5HIU
 | | Structure of the TSC2 N-terminus | | 分子名称: | GTPase activator-like protein | | 著者 | Zech, R, Kiontke, S, Kummel, D. | | 登録日 | 2016-01-12 | | 公開日 | 2016-08-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis.
J.Biol.Chem., 291, 2016
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8OTV
 | | Crystal structure of NUDT14 complexed with novel compound | | 分子名称: | 1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine, DIMETHYL SULFOXIDE, MAGNESIUM ION, ... | | 著者 | Balikci, E, Feyerherm, C, Bradshaw, W, Seupel, R, Brennan, P.E, Bountra, C, von Delft, F, Huber, K, Structural Genomics Consortium (SGC) | | 登録日 | 2023-04-21 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Unexpected Noncovalent Off-Target Activity of Clinical BTK Inhibitors Leads to Discovery of a Dual NUDT5/14 Antagonist.
J.Med.Chem., 67, 2024
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8P1S
 | | Bifidobacterium asteroides alpha-L-fucosidase (TT1819) in complex with fucose. | | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819), ... | | 著者 | Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N. | | 登録日 | 2023-05-12 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published
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8PKI
 | | Cryo-EM structure of NR5A2-nucleosome complex SHL+5.5 | | 分子名称: | DNA, Histone H2A, Histone H2B type 1-C/E/G, ... | | 著者 | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | | 登録日 | 2023-06-26 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.
Nat.Struct.Mol.Biol., 31, 2024
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8PKJ
 | | Cryo-EM structure of the nucleosome containing Nr5a2 motif at SHL+5.5 | | 分子名称: | DNA, Histone H2A, Histone H2B, ... | | 著者 | Kobayashi, W, Sappler, A, Bollschweiler, D, Kummecke, M, Basquin, J, Arslantas, E, Ruangroengkulrith, S, Hornberger, R, Duderstadt, K, Tachibana, K. | | 登録日 | 2023-06-26 | | 公開日 | 2024-02-28 | | 最終更新日 | 2024-05-29 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition.
Nat.Struct.Mol.Biol., 31, 2024
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1ZXJ
 | | Crystal structure of the hypthetical Mycoplasma protein, MPN555 | | 分子名称: | Hypothetical protein MG377 homolog | | 著者 | Schulze-Gahmen, U, Aono, S, Shengfeng, C, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC) | | 登録日 | 2005-06-08 | | 公開日 | 2005-07-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.
Acta Crystallogr.,Sect.D, 61, 2005
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5FO2
 | | Structure of human transthyretin mutant A108I | | 分子名称: | TRANSTHYRETIN | | 著者 | Varejao, N, Santanna, R, Saraiva, M.J, Gallego, P, Ventura, S, Reverter, D. | | 登録日 | 2015-11-17 | | 公開日 | 2016-11-30 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation.
Sci Rep, 7, 2017
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8P1R
 | | Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant. | | 分子名称: | 1,2-ETHANEDIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant, MAGNESIUM ION | | 著者 | Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N. | | 登録日 | 2023-05-12 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.659 Å) | | 主引用文献 | Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published
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8P1Z
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8P19
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8P14
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8P1P
 | | USP28 in complex with AZ1 | | 分子名称: | 2-[[5-bromanyl-2-[[4-fluoranyl-3-(trifluoromethyl)phenyl]methoxy]phenyl]methylamino]ethanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Sauer, F, Karal-Nair, R, Kisker, C. | | 登録日 | 2023-05-12 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | USP28 in complex with AZ1
To Be Published
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8P1Q
 | | USP28 in complex with FT206 | | 分子名称: | 3-azanyl-N-[(2S)-6-[(1S,5R)-3,8-diazabicyclo[3.2.1]octan-3-yl]-1,2,3,4-tetrahydronaphthalen-2-yl]-6-methyl-thieno[2,3-b]pyridine-2-carboxamide, DIMETHYL SULFOXIDE, Ubiquitin carboxyl-terminal hydrolase 28 | | 著者 | Sauer, F, Karal Nair, R, Kisker, C. | | 登録日 | 2023-05-12 | | 公開日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | USP28 in complex with FT206
To Be Published
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8P1Y
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8P4T
 | | The spike complex of the Lujo Virus | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycoprotein, ... | | 著者 | Eilon-Ashkenazy, M, Diskin, R. | | 登録日 | 2023-05-23 | | 公開日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | | 主引用文献 | The spike complex of the Lujo Virus
To Be Published
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8P2E
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8OX2
 | | BRICHOS trimer | | 分子名称: | Pulmonary surfactant-associated protein C | | 著者 | Ghosh, D, Torres, F, Guentert, P, Riek, R. | | 登録日 | 2023-04-30 | | 公開日 | 2024-06-26 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The inhibitory action of the chaperone BRICHOS against the alpha-Synuclein secondary nucleation pathway at near-atomic resolution
To Be Published
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3J0G
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3I6S
 | | Crystal Structure of the plant subtilisin-like protease SBT3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Subtilisin-like protease, alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Rose, R, Ottmann, C. | | 登録日 | 2009-07-07 | | 公開日 | 2010-01-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis for Ca2+-independence and activation by homodimerization of tomato subtilase 3.
Proc.Natl.Acad.Sci.USA, 106, 2009
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