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PDB: 124 results

2I81
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Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced
Descriptor: 2-Cys Peroxiredoxin
Authors:Artz, J.D, Qiu, W, Dong, A, Lew, J, Ren, H, Zhao, Y, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
Deposit date:2006-08-31
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal Structure of Plasmodium vivax 2-Cys Peroxiredoxin, Reduced
To be published
3JWP
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Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
Descriptor: ADENOSINE MONOPHOSPHATE, TRIETHYLENE GLYCOL, Transcriptional regulatory protein sir2 homologue, ...
Authors:Wernimont, A.K, Hutchinson, A, Lin, Y.H, MacKenzie, F, Senisterra, G, Allali-Hassanali, A, Vedadi, M, Ravichandran, M, Cossar, D, Kozieradzki, I, Zhao, Y, Schapira, M, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Qiu, W, Brand, V, Structural Genomics Consortium (SGC)
Deposit date:2009-09-18
Release date:2009-10-20
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
TO BE PUBLISHED
3P8A
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BU of 3p8a by Molmil
Crystal Structure of a hypothetical protein from Staphylococcus aureus
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Lam, R, Qiu, W, Battaile, K, Lam, K, Romanov, V, Chan, T, Pai, E, Chirgadze, N.Y.
Deposit date:2010-10-13
Release date:2011-10-19
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal Structure of a hypothetical protein from Staphylococcus aureus
To be Published
2OQK
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BU of 2oqk by Molmil
Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A
Descriptor: Putative translation initiation factor eIF-1A, SULFATE ION
Authors:Dong, A, Lew, J, Zhao, Y, Hassanali, A, Lin, L, Qiu, W, Brokx, S.J, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Altamentova, S, Structural Genomics Consortium (SGC)
Deposit date:2007-01-31
Release date:2007-02-13
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of putative Cryptosporidium parvum translation initiation factor eIF-1A
To be Published
2OWA
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BU of 2owa by Molmil
Crystal structure of putative GTPase activating protein for ADP ribosylation factor from Cryptosporidium parvum (cgd5_1040)
Descriptor: Arfgap-like finger domain containing protein, ZINC ION
Authors:Dong, A, Lew, J, Zhao, Y, Hassanali, A, Lin, L, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC)
Deposit date:2007-02-15
Release date:2007-02-27
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of putative GTPase activating protein for ADP ribosylation factor from Cryptosporidium parvum (cgd5_1040)
To be Published
3S24
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BU of 3s24 by Molmil
Crystal structure of human mRNA guanylyltransferase
Descriptor: SULFATE ION, mRNA-capping enzyme
Authors:Das, K, Chu, C, Thyminski, J.R, Bauman, J.D, Guan, R, Qiu, W, Montelione, G.T, Arnold, E, Shatkin, A.J.
Deposit date:2011-05-16
Release date:2011-06-15
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.0137 Å)
Cite:Structure of the guanylyltransferase domain of human mRNA capping enzyme.
Proc.Natl.Acad.Sci.USA, 108, 2011
2PBF
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Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine
Descriptor: Protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC)
Deposit date:2007-03-28
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of a putative protein-L-isoaspartate O-methyltransferase beta-aspartate methyltransferase (PCMT) from Plasmodium falciparum in complex with S-adenosyl-L-homocysteine
To be Published
2PSS
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BU of 2pss by Molmil
The structure of Plasmodium falciparum spermidine synthase in its apo-form
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, SULFATE ION, ...
Authors:Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
Deposit date:2007-05-07
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2PT6
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The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ...
Authors:Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
Deposit date:2007-05-08
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
2PLW
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Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052).
Descriptor: Ribosomal RNA methyltransferase, putative, S-ADENOSYLMETHIONINE, ...
Authors:Wernimont, A.K, Hassanali, A, Lin, L, Lew, J, Zhao, Y, Ravichandran, M, Wasney, G, Vedadi, M, Kozieradzki, I, Schapira, M, Bochkarev, A, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Hui, R, Qiu, W, Structural Genomics Consortium (SGC)
Deposit date:2007-04-20
Release date:2007-05-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a ribosomal RNA methyltransferase, putative, from Plasmodium falciparum (PF13_0052).
To be Published
2PT9
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The structure of Plasmodium falciparum spermidine synthase in complex with decarboxylated S-adenosylmethionine and the inhibitor cis-4-methylcyclohexylamine (4MCHA)
Descriptor: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-[(S)-(3-AMINOPROPYL)(METHYL)-LAMBDA~4~-SULFANYL]-5'-DEOXYADENOSINE, GLYCEROL, ...
Authors:Dufe, V.T, Qiu, W, Muller, I.B, Hui, R, Walter, R.D, Al-Karadaghi, S, Structural Genomics Consortium (SGC)
Deposit date:2007-05-08
Release date:2008-04-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
4EF5
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BU of 4ef5 by Molmil
Crystal structure of STING CTD
Descriptor: Transmembrane protein 173
Authors:Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J.
Deposit date:2012-03-29
Release date:2012-05-16
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
9BHJ
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BU of 9bhj by Molmil
MerTK in complex with small molecule 6-{1-[([1,1'-biphenyl]-4-yl)carbamoyl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide
Descriptor: 6-{1-[([1,1'-biphenyl]-4-yl)carbamoyl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:Jakob, C.G, Qiu, W.
Deposit date:2024-04-20
Release date:2024-10-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.294 Å)
Cite:Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement.
J.Med.Chem., 67, 2024
9BHK
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MerTK in complex with small molecule inhibitor 6-{1-[6-(3-hydroxy-3-methylbutoxy)-1,3-benzoxazol-2-yl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide
Descriptor: 6-{1-[6-(3-hydroxy-3-methylbutoxy)-1,3-benzoxazol-2-yl]azetidin-3-yl}-3-[(1-methyl-1H-pyrazol-4-yl)amino]pyrazine-2-carboxamide, CHLORIDE ION, Tyrosine-protein kinase Mer
Authors:Jakob, C.G, Gurbani, D, Qiu, W.
Deposit date:2024-04-20
Release date:2024-10-09
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.106 Å)
Cite:Discovery of Potent Azetidine-Benzoxazole MerTK Inhibitors with In Vivo Target Engagement.
J.Med.Chem., 67, 2024
7UCX
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BU of 7ucx by Molmil
LRP8 11H1 Fab complexed to a cyclized CR1 peptide
Descriptor: 11H1 Fab Heavy chain, 11H1 Fab Light chain, Cyclized CR1 peptide, ...
Authors:Argiriadi, M.A, Deng, K, Egan, D, Gao, L, Gizatullin, F, Harlan, J, Karaoglu, D, Qiu, W, Goodearl, A.
Deposit date:2022-03-17
Release date:2023-01-18
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:The use of cyclic peptide antigens to generate LRP8 specific antibodies
Front Drug Discov (Lausanne), 2, 2023
7UAD
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BU of 7uad by Molmil
Crystal structure of human PTPN2 with inhibitor ABBV-CLS-484
Descriptor: 5-{(7R)-1-fluoro-3-hydroxy-7-[(3-methylbutyl)amino]-5,6,7,8-tetrahydronaphthalen-2-yl}-1lambda~6~,2,5-thiadiazolidine-1,1,3-trione, Tyrosine-protein phosphatase non-receptor type 2
Authors:Longenecker, K.L, Qiu, W, Sun, Q, Frost, J.M.
Deposit date:2022-03-12
Release date:2023-07-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.044 Å)
Cite:The PTPN2/PTPN1 inhibitor ABBV-CLS-484 unleashes potent anti-tumour immunity.
Nature, 622, 2023
6P9E
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BU of 6p9e by Molmil
Crystal structure of IL-36gamma complexed to A-552
Descriptor: (2S)-2-{[4-(3-amino-4-methylphenyl)-6-methylpyrimidin-2-yl]oxy}-3-methoxy-3,3-diphenylpropanoic acid, Interleukin-36 gamma
Authors:Argiriadi, M.A, Todorovic, T, Su, Z, Putman, B, Kakavas, S.J, Salte, K.M, McDonald, H.A, Wetter, J.B, Paulsboe, S.E, Sun, Q, Gerstein, C.E, Medina, L, Sielaff, B, Sadhukhan, R, Stockmann, H, Richardson, P.L, Qiu, W, Henry, R.F, Herold, J.M, Shotwell, J.B, McGaraughty, S.P, Honore, P, Gopalakrishnan, S.M, Sun, C.C, Scott, V.E.
Deposit date:2019-06-10
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Small Molecule IL-36 gamma Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Sci Rep, 9, 2019
3EFZ
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Crystal Structure of a 14-3-3 protein from cryptosporidium parvum (cgd1_2980)
Descriptor: 1,2-ETHANEDIOL, 14-3-3 protein
Authors:Wernimont, A.K, Dong, A, Qiu, W, Lew, J, Wasney, G.A, Vedadi, M, Kozieradzki, I, Zhao, Y, Ren, H, Alam, Z, Lin, Y.H, Sundstrom, M, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
Deposit date:2008-09-10
Release date:2008-09-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
3K35
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Crystal Structure of Human SIRT6
Descriptor: ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-6, SULFATE ION, ...
Authors:Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC)
Deposit date:2009-10-01
Release date:2009-12-08
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
2NPM
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BU of 2npm by Molmil
crystal structure of Cryptosporidium parvum 14-3-3 protein in complex with peptide
Descriptor: 14-3-3 domain containing protein, CONSENSUS PEPTIDE FOR 14-3-3 PROTEINS
Authors:Dong, A, Lew, J, Wasney, G, Ren, H, Lin, L, Hassanali, A, Qiu, W, Zhao, Y, Doyle, D, Vedadi, M, Koeieradzki, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Brokx, S, Structural Genomics Consortium (SGC)
Deposit date:2006-10-27
Release date:2006-11-07
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Characterization of 14-3-3 proteins from Cryptosporidium parvum.
Plos One, 6, 2011
3PKJ
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Human SIRT6 crystal structure in complex with 2'-N-Acetyl ADP ribose
Descriptor: NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ...
Authors:Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC)
Deposit date:2010-11-11
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
3PKI
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Human SIRT6 crystal structure in complex with ADP ribose
Descriptor: NAD-dependent deacetylase sirtuin-6, SULFATE ION, UNKNOWN ATOM OR ION, ...
Authors:Pan, P.W, Dong, A, Qiu, W, Loppnau, P, Wang, J, Ravichandran, M, Bochkarev, A, Bountra, C, Weigelt, J, Arrowsmith, C.H, Min, J, Edwards, A.M, Structural Genomics Consortium (SGC)
Deposit date:2010-11-11
Release date:2011-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structure and biochemical functions of SIRT6.
J.Biol.Chem., 286, 2011
8FG2
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SARS-CoV-2 Nucleocapsid dimer structure determined from COVID-19 patients
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-12
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023
8FD5
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BU of 8fd5 by Molmil
Nucleocapsid monomer structure from SARS-CoV-2
Descriptor: Nucleoprotein
Authors:Casasanta, M, Jonaid, G.M, Kaylor, L, Luqiu, W, DiCecco, L, Solares, M, Berry, S, Kelly, D.F.
Deposit date:2022-12-02
Release date:2023-01-11
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (4.57 Å)
Cite:Structural Insights of the SARS-CoV-2 Nucleocapsid Protein: Implications for the Inner-workings of Rapid Antigen Tests.
Microsc Microanal, 29, 2023

227561

PDB entries from 2024-11-20

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