2O7M
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![BU of 2o7m by Molmil](/molmil-images/mine/2o7m) | The C-terminal loop of the homing endonuclease I-CreI is essential for DNA binding and cleavage. Identification of a novel site for specificity engineering in the I-CreI scaffold | 分子名称: | DNA endonuclease I-CreI | 著者 | Prieto, J, Redondo, P, Padro, D, Blanco, F.J, Paques, F, Montoya, G. | 登録日 | 2006-12-11 | 公開日 | 2007-10-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The C-terminal loop of the homing endonuclease I-CreI is essential for site recognition, DNA binding and cleavage Nucleic Acids Res., 35, 2007
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5A0M
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![BU of 5a0m by Molmil](/molmil-images/mine/5a0m) | THE CRYSTAL STRUCTURE OF I-SCEI IN COMPLEX WITH ITS TARGET DNA IN THE PRESENCE OF MN | 分子名称: | 5'-D(*CP*AP*CP*GP*CP*TP*AP*GP*GP*GP*AP*TP*AP*AP)-3', 5'-D(*CP*AP*GP*GP*GP*TP*AP*AP*TP*AP*CP)-3', 5'-D(*CP*CP*CP*TP*AP*GP*CP*GP*TP)-3', ... | 著者 | Prieto, J, Redondo, P, Merino, N, Villate, M, Blanco, F.J, Molina, R. | 登録日 | 2015-04-21 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the I-Scei Nuclease Complexed with its DsDNA Target and Three Catalytic Metal Ions. Acta Crystallogr.,Sect.F, 72, 2016
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4UT0
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![BU of 4ut0 by Molmil](/molmil-images/mine/4ut0) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 10 DAYS INCUBATION IN 5MM MN (STATE 7) | 分子名称: | 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*CP)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*CP)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', ... | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-07-17 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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8DE5
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![BU of 8de5 by Molmil](/molmil-images/mine/8de5) | Structure of glyceraldehyde-3-phosphate dehydrogenase from Paracoccidioides lutzii | 分子名称: | D-galactonic acid, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... | 著者 | Hernandez-Prieto, J.H, Martini, V.P, Iulek, J. | 登録日 | 2022-06-19 | 公開日 | 2023-06-21 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structure of glyceraldehyde-3-phosphate dehydrogenase from Paracoccidioides lutzii in complex with an aldonic sugar acid. Biochimie, 218, 2023
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3MXA
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![BU of 3mxa by Molmil](/molmil-images/mine/3mxa) | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus | 分子名称: | DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*C)-3'), DNA (5'-D(P*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ... | 著者 | Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G. | 登録日 | 2010-05-07 | 公開日 | 2010-10-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Res., 39, 2011
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3MX9
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![BU of 3mx9 by Molmil](/molmil-images/mine/3mx9) | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus | 分子名称: | CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ... | 著者 | Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G. | 登録日 | 2010-05-07 | 公開日 | 2010-10-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Res., 39, 2011
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3MXB
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![BU of 3mxb by Molmil](/molmil-images/mine/3mxb) | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus | 分子名称: | CALCIUM ION, DNA (5'-D(*TP*CP*TP*GP*GP*CP*TP*GP*AP*GP*GP*TP*AP*CP*CP*TP*GP*AP*GP*AP*AP*CP*AP*A)-3'), DNA (5'-D(*TP*TP*GP*TP*TP*CP*TP*CP*AP*GP*GP*TP*AP*CP*CP*TP*CP*AP*GP*CP*CP*AP*GP*A)-3'), ... | 著者 | Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Montoya, G. | 登録日 | 2010-05-07 | 公開日 | 2010-10-06 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus. Nucleic Acids Res., 39, 2011
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4UNC
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![BU of 4unc by Molmil](/molmil-images/mine/4unc) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8 DAYS INCUBATION IN 5MM MN (STATE 6) | 分子名称: | 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', ... | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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4UNB
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![BU of 4unb by Molmil](/molmil-images/mine/4unb) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 6 DAYS INCUBATION IN 5MM MN (STATE 5) | 分子名称: | 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*A)-3', ... | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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2KG4
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![BU of 2kg4 by Molmil](/molmil-images/mine/2kg4) | Three-dimensional structure of human Gadd45alpha in solution by NMR | 分子名称: | Growth arrest and DNA-damage-inducible protein GADD45 alpha | 著者 | Sanchez, R, Pantoja-Uceda, D, Prieto, J, Diercks, T, Campos-Olivas, R, Blanco, F.J. | 登録日 | 2009-03-04 | 公開日 | 2009-03-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase J.Biol.Chem., 285, 2010
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4UN8
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![BU of 4un8 by Molmil](/molmil-images/mine/4un8) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2) | 分子名称: | 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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4UNA
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![BU of 4una by Molmil](/molmil-images/mine/4una) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 2 DAYS INCUBATION IN 5MM MN (STATE 4) | 分子名称: | 25MER, 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*C)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', ... | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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4UN9
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![BU of 4un9 by Molmil](/molmil-images/mine/4un9) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 8H INCUBATION IN 5MM MN (STATE 3) | 分子名称: | 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2015-01-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.734 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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4UN7
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![BU of 4un7 by Molmil](/molmil-images/mine/4un7) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA BEFORE INCUBATION IN 5MM MN (STATE 1) | 分子名称: | 25MER, HOMING ENDONUCLEASE I-DMOI, ZINC ION | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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2VS8
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![BU of 2vs8 by Molmil](/molmil-images/mine/2vs8) | The crystal structure of I-DmoI in complex with DNA and Mn | 分子名称: | 5'-D(*CP*CP*GP*GP*CP*AP*AP* GP*GP*CP)-3', 5'-D(*CP*GP*CP*GP*CP*CP*GP*GP*AP*AP *CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP *GP*TP*AP*A)-3', ... | 著者 | Marcaida, M.J, Prieto, J, Redondo, P, Nadra, A.D, Alibes, A, Serrano, L, Grizot, S, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2008-04-21 | 公開日 | 2008-11-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of I-Dmoi in Complex with its Target DNA Provides New Insights Into Meganuclease Engineering. Proc.Natl.Acad.Sci.USA, 105, 2008
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6FB6
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![BU of 6fb6 by Molmil](/molmil-images/mine/6fb6) | |
6FB9
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![BU of 6fb9 by Molmil](/molmil-images/mine/6fb9) | |
6FB5
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![BU of 6fb5 by Molmil](/molmil-images/mine/6fb5) | |
6FB0
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![BU of 6fb0 by Molmil](/molmil-images/mine/6fb0) | |
6FB2
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![BU of 6fb2 by Molmil](/molmil-images/mine/6fb2) | |
6FB1
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![BU of 6fb1 by Molmil](/molmil-images/mine/6fb1) | |
6FB8
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![BU of 6fb8 by Molmil](/molmil-images/mine/6fb8) | |
6FB7
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![BU of 6fb7 by Molmil](/molmil-images/mine/6fb7) | |
2XE0
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![BU of 2xe0 by Molmil](/molmil-images/mine/2xe0) | Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus | 分子名称: | 24MER DNA, ACETATE ION, I-CREI V2V3 VARIANT, ... | 著者 | Munoz, I.G, Prieto, J, Subramanian, S, Coloma, J, Redondo, P, Villate, M, Merino, N, Marenchino, M, D'Abramo, M, Gervasio, F.L, Grizot, S, Daboussi, F, Smith, J, Chion-Sotine, I, Paques, F, Duchateau, P, Alibes, A, Stricher, F, Serrano, L, Blanco, F.J, Montoya, G. | 登録日 | 2010-05-10 | 公開日 | 2010-09-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Molecular Basis of Engineered Meganuclease Targeting of the Endogenous Human Rag1 Locus Nucleic Acids Res., 39, 2011
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2VBL
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![BU of 2vbl by Molmil](/molmil-images/mine/2vbl) | Molecular basis of human XPC gene recognition and cleavage by engineered homing endonuclease heterodimers | 分子名称: | 5'-D(*DA*DA*DA*DA*DG*DG*DC*DA*DG*DAP)-3', 5'-D(*DA*DG*DG*DA*DT*DC*DC*DT*DA*DAP)-3', 5'-D(*DT*DC*DT*DG*DC*DC*DT*DT*DT*DT*DT*DT *DGP*DAP)-3', ... | 著者 | Redondo, P, Prieto, J, Munoz, I.G, Alibes, A, Stricher, F, Serrano, L, Arnould, S, Perez, C, Cabaniols, J.P, Duchateau, P, Paques, F, Blanco, F.J, Montoya, G. | 登録日 | 2007-09-14 | 公開日 | 2008-10-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Molecular Basis of Xeroderma Pigmentosum Group C DNA Recognition by Engineered Meganucleases Nature, 456, 2008
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