2Y91
| Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with clavulanic acid | 分子名称: | 5-HYDROXY-3-OXOPENTANOIC ACID, BETA-LACTAMASE, CITRIC ACID, ... | 著者 | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | 登録日 | 2011-02-11 | 公開日 | 2012-02-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Novel Fragments of Clavulanate Observed in the Structure of the Class a Beta-Lactamase from Bacillus Licheniformis Bs3. J.Antimicrob.Chemother., 67, 2012
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5AEB
| Crystal structure of the class B3 di-zinc metallo-beta-lactamase LRA- 12 from an Alaskan soil metagenome. | 分子名称: | COBALT (II) ION, LRA-12, SULFATE ION, ... | 著者 | Power, P, Herman, R, Kerff, F, Bouillenne, F, Rodriguez, M.M, Galleni, M, Handelsman, J, Gutkind, G, Charlier, P, Sauvage, E. | 登録日 | 2015-08-27 | 公開日 | 2015-09-16 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure and kinetic analysis of the class B3 di-zinc metallo-beta-lactamase LRA-12 from an Alaskan soil metagenome. PLoS ONE, 12, 2017
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6BN3
| CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | 著者 | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | 登録日 | 2017-11-16 | 公開日 | 2018-11-21 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.278 Å) | 主引用文献 | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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6BPF
| CTX-M-151 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 Angstrom resolution | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | 著者 | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | 登録日 | 2017-11-23 | 公開日 | 2018-11-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.318 Å) | 主引用文献 | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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6D3G
| PER-2 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 2.4 Angstrom resolution | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, TETRAETHYLENE GLYCOL | 著者 | Power, P, Ruggiero, M, Gutkind, G, Bonomo, R, Klinke, S. | 登録日 | 2018-04-16 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.398 Å) | 主引用文献 | Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam. Antimicrob.Agents Chemother., 63, 2019
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6DGU
| PER-2 class A extended-spectrum beta-lactamase crystal structure at 2.69 Angstrom resolution | 分子名称: | Beta-lactamase | 著者 | Power, P, Ruggiero, M, Gutkind, G, Bonomo, R, Klinke, S. | 登録日 | 2018-05-18 | 公開日 | 2019-05-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.691 Å) | 主引用文献 | Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam. Antimicrob.Agents Chemother., 63, 2019
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8EK9
| Crystal structure of the class A carbapenemase CRH-1 in complex with avibactam at 1.4 Angstrom resolution | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | 著者 | Power, P, Brunetti, F, Ghiglione, B, Guardabassi, L, Gutkind, G, Klinke, S. | 登録日 | 2022-09-20 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC beta-Lactamases. Antimicrob.Agents Chemother., 67, 2023
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8EHU
| Crystal structure of the environmental CRH-1 class A carbapenemase at 1.1 Angstrom resolution | 分子名称: | Beta-lactamase | 著者 | Power, P, Brunetti, F, Ghiglione, B, Guardabassi, L, Gutkind, G, Klinke, S. | 登録日 | 2022-09-14 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Biochemical and Structural Characterization of CRH-1, a Carbapenemase from Chromobacterium haemolyticum Related to KPC beta-Lactamases. Antimicrob.Agents Chemother., 67, 2023
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8EHH
| Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution | 分子名称: | (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | 著者 | Power, P, Ghiglione, B, Bonomo, R.A, Rodriguez, M.M, Gutkind, G, Klinke, S. | 登録日 | 2022-09-14 | 公開日 | 2023-09-20 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.03 Å) | 主引用文献 | Biochemical and structural evidences of the activity of relebactam as inhibitor of the extended-spectrum beta-lactamase CTX-M-96. To be published
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8EO5
| Crystal structure of the class A beta-lactamase precursor LRA-5 from an Alaskan soil metagenome at 1.8 Angstrom resolution | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LRA-5 | 著者 | Power, P, D'Amico Gonzalez, G, Centron, D, Gutkind, G, Handelsman, J, Klinke, S. | 登録日 | 2022-10-02 | 公開日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Playing beta-Lactamase Evolution: Metagenomic Class A beta-Lactamase LRA-5 is an Inactive Enzyme Capable of Rendering an Active beta-Lactamase by Introduction of Y69Q and V166E Substitutions to be published
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8EO7
| Crystal structure of metagenomic beta-lactamase LRA-5 Y69Q/V166E mutant at 2.15 Angstrom resolution | 分子名称: | beta-lactamase | 著者 | Power, P, D'Amico Gonzalez, G, Centron, D, Gutkind, G, Handelsman, J, Klinke, S. | 登録日 | 2022-10-02 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Playing beta-Lactamase Evolution: Metagenomic Class A beta-Lactamase LRA-5 is an Inactive Enzyme Capable of Rendering an Active beta-Lactamase by Introduction of Y69Q and V166E Substitutions to be published
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8EO6
| Crystal structure of metagenomic class A beta-lactamase precursor LRA-5 in complex with ceftazidime at 2.35 Angstrom resolution | 分子名称: | ACYLATED CEFTAZIDIME, LRA-5 | 著者 | Power, P, D'Amico Gonzalez, G, Centron, D, Gutkind, G, Handelsman, J, Klinke, S. | 登録日 | 2022-10-02 | 公開日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Playing beta-Lactamase Evolution: Metagenomic Class A beta-Lactamase LRA-5 is an Inactive Enzyme Capable of Rendering an Active beta-Lactamase by Introduction of Y69Q and V166E Substitutions to be published
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4A5R
| Crystal structure of class A beta-lactamase from Bacillus licheniformis BS3 with tazobactam | 分子名称: | BETA-LACTAMASE, CARBON DIOXIDE, CITRIC ACID, ... | 著者 | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | 登録日 | 2011-10-28 | 公開日 | 2012-10-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of Class a Beta-Lactamase from Bacillus Licheniformis Inhibited by Tazobactam To be Published
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3ZNT
| Crystal structure of OXA-24 class D beta-lactamase with tazobactam | 分子名称: | BETA-LACTAMASE, SULFATE ION, TAZOBACTAM INTERMEDIATE | 著者 | Power, P, Sauvage, E, Herman, R, Kerff, F, Charlier, P. | 登録日 | 2013-02-18 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of Oxa-24 Beta-Lactamase Inhibited by Tazobactam To be Published
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3ZNY
| Crystal structure of the class A extended-spectrum beta-lactamase CTX- M-96, a natural D240G mutant derived from CTX-M-12 | 分子名称: | CTX-M-12A ENZYME | 著者 | Power, P, Herman, R, Bouillenne, F, Ghiglione, B, Rodriguez, M.M, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E. | 登録日 | 2013-02-18 | 公開日 | 2014-01-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Structural and Kinetic Insights Into the "Ceftazidimase" Behavior of the Extended-Spectrum Beta-Lactamase Ctx-M-96. Biochemistry, 54, 2015
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4D2O
| Crystal structure of the class A extended-spectrum beta-lactamase PER- 2 | 分子名称: | PER-2 BETA-LACTAMASE | 著者 | Power, P, Herman, R, Ruggiero, M, Kerff, F, Galleni, M, Gutkind, G, Charlier, P, Sauvage, E. | 登録日 | 2014-05-12 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure of the Extended-Spectrum Beta-Lactamase Per- 2 and Insights Into the Role of Specific Residues in the Interaction with Beta-Lactams and Beta-Lactamase Inhibitors. Antimicrob.Agents Chemother., 58, 2014
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