6D3G
PER-2 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 2.4 Angstrom resolution
Summary for 6D3G
Entry DOI | 10.2210/pdb6d3g/pdb |
Descriptor | Beta-lactamase, (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, TETRAETHYLENE GLYCOL, ... (4 entities in total) |
Functional Keywords | dbo, penicilloil-serine-transferase, antibiotic resistance, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Citrobacter freundii |
Total number of polymer chains | 4 |
Total formula weight | 125088.58 |
Authors | Power, P.,Ruggiero, M.,Gutkind, G.,Bonomo, R.,Klinke, S. (deposition date: 2018-04-16, release date: 2019-04-24, Last modification date: 2023-10-04) |
Primary citation | Ruggiero, M.,Papp-Wallace, K.M.,Brunetti, F.,Barnes, M.D.,Bonomo, R.A.,Gutkind, G.,Klinke, S.,Power, P. Structural Insights into the Inhibition of the Extended-Spectrum beta-Lactamase PER-2 by Avibactam. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31235626DOI: 10.1128/AAC.00487-19 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.398 Å) |
Structure validation
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