1E21
| Ribonuclease 1 des1-7 Crystal Structure at 1.9A | 分子名称: | RIBONUCLEASE 1 | 著者 | Pous, J, Mallorqui-Fernandez, G, Peracaula, R, Terzyan, S.S, Futami, J, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Ruth, F.X, Coll, M. | 登録日 | 2000-05-15 | 公開日 | 2001-05-03 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Three-Dimensional Crystal Structure of Human Rnase 1Dn7 at 1.9A Resolution Acta Crystallogr.,Sect.D, 57, 2001
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2QS6
| Structure of a Hoogsteen antiparallel duplex with extra-helical thymines | 分子名称: | DNA (5'-D(*DAP*DTP*DAP*DTP*DAP*DTP*DCP*DT)-3') | 著者 | Pous, J, Urpi, L, Subirana, J.A, Gouyette, C, Navaza, J, Campos, J.L. | 登録日 | 2007-07-30 | 公開日 | 2008-03-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.08 Å) | 主引用文献 | Stabilization by extra-helical thymines of a DNA duplex with Hoogsteen base pairs. J.Am.Chem.Soc., 130, 2008
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1DZA
| 3-D structure of a HP-RNase | 分子名称: | RIBONUCLEASE 1 | 著者 | Pous, J, Canals, A, Terzyan, S.S, Guasch, A, Benito, A, Ribo, M, Vilanova, M, Coll, M. | 登録日 | 2000-02-21 | 公開日 | 2001-02-16 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Three-Dimensional Structure of a Human Pancreatic Ribonuclease Variant, a Step Forward in the Design of Cytotoxic Ribonucleases J.Mol.Biol., 303, 2000
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8PQN
| NQO1 bound to RBS-10 | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, NAD(P)H dehydrogenase [quinone] 1, ~{N}-[4-[(3-methylphenyl)carbonylamino]phenyl]-5-nitro-furan-2-carboxamide | 著者 | Pous, J, Jose-Duran, F, Mayor-Ruiz, C, Riera, A. | 登録日 | 2023-07-11 | 公開日 | 2024-01-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Discovery and Mechanistic Elucidation of NQO1-Bioactivatable Small Molecules That Overcome Resistance to Degraders. Angew.Chem.Int.Ed.Engl., 63, 2024
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8ACM
| Crystal structure of WT p38alpha | 分子名称: | 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAGNESIUM ION, Mitogen-activated protein kinase 14 | 著者 | Pous, J, Baginski, B, Gonzalez, L, Macias, M.J, Nebreda, A.R. | 登録日 | 2022-07-05 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Crystal structure of WT p38alpha Res Sq
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8ACO
| Crystal structure of WT p38alpha | 分子名称: | 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAGNESIUM ION, Mitogen-activated protein kinase 14 | 著者 | Pous, J, Baginski, B, Gonzalez, L, Macias, M.J, Nebreda, A.R. | 登録日 | 2022-07-05 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of WT p38alpha Res Sq
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3EY0
| A new form of DNA-drug interaction in the minor groove of a coiled coil | 分子名称: | 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, 5'-D(*DAP*DTP*DAP*DTP*DAP*DTP*DAP*DTP*DAP*DT)-3', MAGNESIUM ION | 著者 | Pous, J, Moreno, T, Subirana, J.A, Campos, J.L. | 登録日 | 2008-10-17 | 公開日 | 2009-10-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Coiled-coil conformation of a pentamidine-DNA complex Acta Crystallogr.,Sect.D, 66, 2010
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2GSY
| The 2.6A structure of Infectious Bursal Virus Derived T=1 Particles | 分子名称: | CALCIUM ION, polyprotein | 著者 | Garriga, D, Querol-Audi, J, Abaitua, F, Saugar, I, Pous, J, Verdaguer, N, Caston, J.R, Rodriguez, J.F. | 登録日 | 2006-04-27 | 公開日 | 2006-07-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The 2.6-angstrom structure of infectious bursal disease virus-derived t=1 particles reveals new stabilizing elements of the virus capsid. J.Virol., 80, 2006
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7PVU
| Crystal structure of p38alpha C162S in complex with CAS2094511-69-8, P 1 21 1 | 分子名称: | Mitogen-activated protein kinase 14, N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)-2-fluorobenzene-1-sulfonamide | 著者 | Baginski, B, Pous, J, Gonzalez, L, Macias, M.J, Nebreda, A.R. | 登録日 | 2021-10-05 | 公開日 | 2023-05-17 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.154 Å) | 主引用文献 | Characterization of p38 alpha autophosphorylation inhibitors that target the non-canonical activation pathway. Nat Commun, 14, 2023
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6TJP
| Crystal structure of T7 bacteriophage portal protein, 13mer, closed valve - P212121 | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Fernandez, F.J, Machon, C, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-11-26 | 公開日 | 2020-12-16 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | 主引用文献 | Using a partial atomic model from medium-resolution cryo-EM to solve a large crystal structure. Acta Crystallogr D Struct Biol, 77, 2021
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1DYT
| X-ray crystal structure of ECP (RNase 3) at 1.75 A | 分子名称: | CITRIC ACID, EOSINOPHIL CATIONIC PROTEIN, FE (III) ION | 著者 | Mallorqui-Fernandez, G, Pous, J, Peracaula, R, Maeda, T, Tada, H, Yamada, H, Seno, M, De Llorens, R, Gomis-Rueth, F.X, Coll, M. | 登録日 | 2000-02-08 | 公開日 | 2001-02-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Three-Dimensional Crystal Structure of Human Eosinophil Cationic Protein (Rnase 3) at 1.75 A Resolution. J.Mol.Biol., 300, 2000
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1WCD
| Crystal structure of IBDV T1 virus-like particle reveals a missing link in icosahedral viruses evolution | 分子名称: | MAJOR STRUCTURAL PROTEIN VP2 | 著者 | Coulibaly, F, Chevalier, C, Gutsche, I, Pous, J, Bressanelli, S, Navaza, J, Delmas, B, Rey, F.A. | 登録日 | 2004-11-12 | 公開日 | 2005-04-05 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Birnavirus Crystal Structure Reveals Structural Relationships Among Icosahedral Viruses. Cell(Cambridge,Mass.), 120, 2005
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1WCE
| Crystal structure of the T13 IBDV viral particle reveals a missing link in icosahedral viruses evolution | 分子名称: | MAJOR STRUCTURAL PROTEIN VP2 | 著者 | Coulibaly, F, Chevalier, C, Gutsche, I, Pous, J, Bressanelli, S, Navaza, J, Delmas, B, Rey, F.A. | 登録日 | 2004-11-12 | 公開日 | 2005-04-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (7 Å) | 主引用文献 | The Birnavirus Crystal Structure Reveals Structural Relationships Among Icosahedral Viruses. Cell(Cambridge,Mass.), 120, 2005
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3NAP
| Structure of Triatoma Virus (TrV) | 分子名称: | Capsid protein | 著者 | Squires, G, Pous, J. | 登録日 | 2010-06-02 | 公開日 | 2010-07-28 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The crystallographic structure of Triatoma Virus (TrV) highlights the Dicistroviridae and Picornaviridae family differences To be Published
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3DPR
| Human rhinovirus 2 bound to a concatamer of the VLDL receptor module V3 | 分子名称: | CALCIUM ION, LAURIC ACID, LDL-receptor class A 3, ... | 著者 | Querol-Audi, J, Pous, J, Fita, I, Verdaguer, N. | 登録日 | 2008-07-09 | 公開日 | 2009-04-07 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Minor group human rhinovirus-receptor interactions: geometry of multimodular attachment and basis of recognition Febs Lett., 583, 2009
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4NS0
| The C2A domain of Rabphilin 3A in complex with PI(4,5)P2 | 分子名称: | Rabphilin-3A, SULFATE ION, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate | 著者 | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | 登録日 | 2013-11-27 | 公開日 | 2013-12-25 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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4NP9
| Structure of Rabphilin C2A domain bound to IP3 | 分子名称: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Rabphilin-3A, SULFATE ION | 著者 | Guillen, J, Ferrer-Orta, C, Buxaderas, M, Perez-Sanchez, D, Guerrero-Valero, M, Luengo-Gil, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Verdaguer, N, Corbalan-Garcia, S. | 登録日 | 2013-11-21 | 公開日 | 2013-12-25 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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7Z9T
| Crystal structure of p38alpha C162S in complex with ATPgS and CAS 2094667-81-7 (in catalytic site, Y35 out), P 1 21 1 | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Mitogen-activated protein kinase 14, N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)benzenesulfonamide | 著者 | Baginski, B, Pous, J, Gonzalez, L, Macias, M.J, Nebreda, A.R. | 登録日 | 2022-03-21 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Characterization of p38 alpha autophosphorylation inhibitors that target the non-canonical activation pathway. Nat Commun, 14, 2023
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4HL8
| Re-refinement of the vault ribonucleoprotein particle | 分子名称: | Major vault protein | 著者 | Casanas, A, Querol-Audi, J, Guerra, P, Pous, J, Tanaka, H, Tsukihara, T, Verdaguer, V, Fita, I. | 登録日 | 2012-10-16 | 公開日 | 2013-06-05 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | New features of vault architecture and dynamics revealed by novel refinement using the deformable elastic network approach. Acta Crystallogr.,Sect.D, 69, 2013
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6QXM
| Cryo-EM structure of T7 bacteriophage portal protein, 12mer, open valve | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-03-07 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6QWP
| Crystal structure of T7 bacteriophage portal protein, 13mer, closed valve | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-03-06 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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6QX5
| Crystal structure of T7 bacteriophage portal protein, 12mer, closed valve | 分子名称: | Portal protein | 著者 | Fabrega-Ferrer, M, Cuervo, A, Machon, C, Fernandez, F.J, Perez-Luque, R, Pous, J, Vega, M.C, Carrascosa, J.L, Coll, M. | 登録日 | 2019-03-07 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structures of T7 bacteriophage portal and tail suggest a viral DNA retention and ejection mechanism. Nat Commun, 10, 2019
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3EIL
| Structure of B-DNA d(CGTTAATTAACG)2 in the presence of Manganese | 分子名称: | 5'-D(*DCP*DGP*DTP*DTP*DAP*DAP*DTP*DTP*DAP*DAP*DCP*DG)-3', MANGANESE (II) ION | 著者 | Millonig, H, Pous, J, Campos, L.J, Subirana, J.A. | 登録日 | 2008-09-16 | 公開日 | 2009-06-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | The interaction of manganese ions with DNA J.Inorg.Biochem., 103, 2009
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4LT7
| Crystal structure of the c2a domain of rabphilin-3a in complex with a calcium | 分子名称: | CALCIUM ION, Rabphilin-3A | 著者 | Verdaguer, N, Ferrer-Orta, C, Buxaderas, M, Corbalan-Garcia, S, Perez-Sanchez, D, Guerrero-Valero, M, Luengo, G, Pous, J, Guerra, P, Gomez-Fernandez, J.C, Guillen, J. | 登録日 | 2013-07-23 | 公開日 | 2013-12-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1. Proc.Natl.Acad.Sci.USA, 110, 2013
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7Z6I
| Crystal structure of p38alpha C162S in complex with SB20358 and CAS 2094667-81-7 (behind catalytic site; Y35 in), P 21 21 21 | 分子名称: | 4-[4-(4-fluorophenyl)-2-[4-[methyl(oxidanyl)-$l^{3}-sulfanyl]phenyl]-1~{H}-imidazol-5-yl]pyridine, Mitogen-activated protein kinase 14, N-(2-cyclobutyl-1H-1,3-benzodiazol-5-yl)benzenesulfonamide | 著者 | Baginski, B, Pous, J, Gonzalez, L, Macias, M.J, Nebreda, A.R. | 登録日 | 2022-03-11 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Characterization of p38 alpha autophosphorylation inhibitors that target the non-canonical activation pathway. Nat Commun, 14, 2023
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