A new form of DNA-drug interaction in the minor groove of a coiled coil

Summary for 3EY0

Descriptor5'-D(*DAP*DTP*DAP*DTP*DAP*DTP*DAP*DTP*DAP*DT)-3', 1,5-BIS(4-AMIDINOPHENOXY)PENTANE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsdna drug pentamidine coiled-coil all-at, dna
Total number of polymer chains2
Total molecular weight6448.81
Pous, J.,Moreno, T.,Subirana, J.A.,Campos, J.L. (deposition date: 2008-10-17, release date: 2009-10-27, Last modification date: 2011-07-13)
Primary citation
Moreno, T.,Pous, J.,Subirana, J.A.,Campos, J.L.
Coiled-coil conformation of a pentamidine-DNA complex
Acta Crystallogr.,Sect.D, 66:251-257, 2010
PubMed: 20179336 (PDB entries with the same primary citation)
DOI: 10.1107/S0907444909055693
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRSRZ outliers0.30210MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution