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PDB: 106 件
3HNA
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BU of 3hna by Molmil
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and mono-Methylated H3K9 Peptide
分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, Mono-Methylated H3K9 Peptide, ...
著者Min, J, Wu, H, Loppnau, P, Wleigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2009-05-30
公開日2009-06-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
3IHX
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BU of 3ihx by Molmil
Methyltransferase domain of human PR domain-containing protein 10
分子名称: PR domain zinc finger protein 10
著者Amaya, M.F, Dombrovski, L, Ni, S, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Botchkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2009-07-31
公開日2009-08-18
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Methyltransferase domain of human PR domain-containing protein 10
To be Published
1ZRH
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BU of 1zrh by Molmil
Crystal structure of Human heparan sulfate glucosamine 3-O-sulfotransferase 1 in complex with PAP
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Heparan sulfate glucosamine 3-O-sulfotransferase 1
著者Dong, A, Dombrovski, L, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-05-19
公開日2005-06-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Human heparan sulfate glucosamine 3-O-sulfotransferase 1 in complex with PAP
To be Published
2A14
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BU of 2a14 by Molmil
Crystal Structure of Human Indolethylamine N-methyltransferase with SAH
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, indolethylamine N-methyltransferase
著者Dong, A, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-06-17
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Human Indolethylamine N-methyltransferase in complex with SAH.
To be Published
2BZG
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BU of 2bzg by Molmil
Crystal structure of thiopurine S-methyltransferase.
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, S-ADENOSYL-L-HOMOCYSTEINE, THIOPURINE S-METHYLTRANSFERASE
著者Battaile, K.P, Wu, H, Zeng, H, Loppnau, P, Dong, A, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-08-17
公開日2005-08-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Structural Basis of Allele Variation of Human Thiopurine-S-Methyltransferase.
Proteins, 67, 2007
2B4Y
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BU of 2b4y by Molmil
Crystal Structure of Human Sirtuin homolog 5
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5-DIPHOSPHORIBOSE, NAD-dependent deacetylase sirtuin-5, ...
著者Min, J.R, Antoshenko, T, Dong, A, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-09-27
公開日2006-02-28
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of Human Sirtuin homolog 5 in complex with NAD
To be Published
2B9E
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BU of 2b9e by Molmil
Human NSUN5 protein
分子名称: NOL1/NOP2/Sun domain family, member 5 isoform 2, S-ADENOSYLMETHIONINE
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-10-11
公開日2005-10-18
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The Crystal Structure of Human NSUN5 protein in complex with S-adenosyl-L-methionine
To be Published
2AD1
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BU of 2ad1 by Molmil
Human Sulfotransferase SULT1C2
分子名称: Sulfotransferase 1C2
著者Dong, A, Dombrovski, L, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-07-19
公開日2005-08-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
1ZD1
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BU of 1zd1 by Molmil
Human Sulfortransferase SULT4A1
分子名称: GLYCEROL, Sulfotransferase 4A1
著者Dong, A, Dombrovski, L, Loppnau, P, Edwards, A.M, Arrowsmith, C.H, Sundstrom, M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-04-13
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Structural and chemical profiling of the human cytosolic sulfotransferases.
Plos Biol., 5, 2007
2B25
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BU of 2b25 by Molmil
Human putative tRNA(1-methyladenosine)methyltransferase
分子名称: S-ADENOSYLMETHIONINE, UNKNOWN ATOM OR ION, hypothetical protein
著者Tempel, W, Wu, H, Dong, A, Zeng, H, Loppnau, P, Arrowsmith, C, Edwards, A, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-09-16
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human putative tRNA(1-methyladenosine)methyltransferase
To be Published
2AVD
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BU of 2avd by Molmil
Crystal Structure of Human Catechol-O-methyltransferase domain containing 1
分子名称: Catechol-O-methyltransferase, S-ADENOSYLMETHIONINE
著者Min, J.R, Wu, H, Zeng, H, Loppnau, P, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2005-08-29
公開日2005-09-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The Crystal Structure of Human Catechol-O-methyltransferase domain containing 1 in complex with S-adenosyl-L-methionine
To be Published
3C0Y
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BU of 3c0y by Molmil
Crystal structure of catalytic domain of human histone deacetylase HDAC7
分子名称: Histone deacetylase 7a, POTASSIUM ION, ZINC ION
著者Min, J.R, Schuetz, A, Allali-Hassani, A, Loppnau, P, Kwiatkowski, N.P, Mazitschek, R, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Vedadi, M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
2PQ8
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BU of 2pq8 by Molmil
MYST histone acetyltransferase 1
分子名称: COENZYME A, Probable histone acetyltransferase MYST1, UNKNOWN ATOM OR ION, ...
著者Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-05-01
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献MYST histone acetyltransferase 1.
To be Published
2PFR
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BU of 2pfr by Molmil
Human N-acetyltransferase 2
分子名称: Arylamine N-acetyltransferase 2, COENZYME A, SULFATE ION, ...
著者Tempel, W, Wu, H, Dombrovski, L, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Grant, D.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-04-05
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献The Crystal Structure of Human N-acetyltransferase 2 in complex with CoA
to be published
2PXX
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BU of 2pxx by Molmil
Human putative methyltransferase MGC2408
分子名称: S-ADENOSYL-L-HOMOCYSTEINE, UNKNOWN ATOM OR ION, Uncharacterized protein MGC2408
著者Tempel, W, Wu, H, Dombrovsky, L, Zeng, H, Zhu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-05-14
公開日2007-05-22
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene.
Proteins, 74, 2009
3C10
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BU of 3c10 by Molmil
Crystal structure of catalytic domain of human histone deacetylase HDAC7 in complex with Trichostatin A (TSA)
分子名称: Histone deacetylase 7a, POTASSIUM ION, TRICHOSTATIN A, ...
著者Min, J, Schuetz, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2008-01-21
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity.
J.Biol.Chem., 283, 2008
3DB5
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BU of 3db5 by Molmil
Crystal structure of methyltransferase domain of human PR domain-containing protein 4
分子名称: PR domain zinc finger protein 4
著者Amaya, M.F, Zeng, H, Loppnau, P, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-08-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The crystal structure of methyltransferase domain of human PR domain-containing protein 4.
To be Published
2R3A
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BU of 2r3a by Molmil
Methyltransferase domain of human suppressor of variegation 3-9 homolog 2
分子名称: Histone-lysine N-methyltransferase SUV39H2, S-ADENOSYLMETHIONINE, SERINE, ...
著者Lunin, V.V, Wu, H, Zeng, H, Ren, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Min, J, Structural Genomics Consortium (SGC)
登録日2007-08-29
公開日2007-09-11
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
2RFI
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BU of 2rfi by Molmil
Crystal structure of catalytic domain of human euchromatic histone methyltransferase 1 in complex with SAH and dimethylated H3K9 peptide
分子名称: Histone H3, Histone-lysine N-methyltransferase, H3 lysine-9 specific 5, ...
著者Min, J, Wu, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-09-30
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Structural biology of human H3K9 methyltransferases
Plos One, 5, 2010
2REO
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BU of 2reo by Molmil
Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP
分子名称: ADENOSINE-3'-5'-DIPHOSPHATE, Putative sulfotransferase 1C3
著者Tempel, W, Pan, P, Dong, A, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-09-26
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP.
To be Published
3C6G
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Crystal structure of CYP2R1 in complex with vitamin D3
分子名称: (1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-METHYL-1-[(2R)-6-METHYLHEPTAN-2-YL]-2,3,3A,5,6,7-HEXAHYDRO-1H-INDEN-4-YLIDENE]ETHYLI DENE]-4-METHYLIDENE-CYCLOHEXAN-1-OL, Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Cytochrome P450 2R1, ...
著者Strushkevich, N.V, Min, J, Loppnau, P, Tempel, W, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Plotnikov, A.N, Park, H, Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of CYP2R1 in complex with vitamin D3.
J.Mol.Biol., 380, 2008
3CKK
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BU of 3ckk by Molmil
Crystal structure of human methyltransferase-like protein 1
分子名称: GLYCEROL, S-ADENOSYLMETHIONINE, tRNA (guanine-N(7)-)-methyltransferase
著者Dong, A, Zeng, H, Dobrovetsky, E, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Plotnikov, A.N, Wu, H, Structural Genomics Consortium (SGC)
登録日2008-03-16
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of human methyltransferase-like protein 1.
To be Published
3C6M
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BU of 3c6m by Molmil
Crystal structure of human spermine synthase in complex with spermine and 5-methylthioadenosine
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMINE, Spermine synthase
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Pegg, A.E, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.
J.Biol.Chem., 283, 2008
3C6K
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Crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, SPERMIDINE, Spermine synthase
著者Min, J, Wu, H, Zeng, H, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Pegg, A.E, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2008-02-04
公開日2008-02-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of human spermine synthase: implications of substrate binding and catalytic mechanism.
J.Biol.Chem., 283, 2008
2OZU
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BU of 2ozu by Molmil
Crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A
分子名称: ACETAMIDE, ACETYL COENZYME *A, Histone acetyltransferase MYST3, ...
著者Min, J, Wu, H, Dombrovski, L, Bernstein, G, Dong, A, Loppnau, P, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Plotnikov, A.N, Structural Genomics Consortium (SGC)
登録日2007-02-27
公開日2007-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of human MYST histone acetyltransferase 3 in complex with acetylcoenzyme A
To be Published

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