1TLB
 
 | | Yeast coproporphyrinogen oxidase | | Descriptor: | Coproporphyrinogen III oxidase, SULFATE ION | | Authors: | Phillip, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | Deposit date: | 2004-06-09 | | Release date: | 2004-07-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the oxygen-dependent coproporphyrinogen oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
|
|
1JPI
 | | Phe232Leu mutant of human UROD, human uroporphyrinogen III decarboxylase | | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | Deposit date: | 2001-08-02 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
|
|
1JPH
 | | Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase | | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | Deposit date: | 2001-08-02 | | Release date: | 2001-12-19 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
|
|
1JPK
 | | Gly156Asp mutant of Human UroD, human uroporphyrinogen III decarboxylase | | Descriptor: | UROPORPHYRINOGEN DECARBOXYLASE | | Authors: | Phillips, J.D, Parker, T.L, Schubert, H.L, Whitby, F.G, Hill, C.P, Kushner, J.P. | | Deposit date: | 2001-08-02 | | Release date: | 2001-12-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Functional consequences of naturally occurring mutations in human uroporphyrinogen decarboxylase.
Blood, 98, 2001
|
|
1TK1
 | | YEAST OXYGEN-DEPENDENT COPROPORPHYRINOGEN OXIDASE | | Descriptor: | Coproporphyrinogen III oxidase | | Authors: | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | Deposit date: | 2004-06-08 | | Release date: | 2004-07-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
|
|
1TKL
 | | Yeast Oxygen-Dependent Coproporphyrinogen Oxidase | | Descriptor: | Coproporphyrinogen III oxidase | | Authors: | Phillips, J.D, Whitby, F.G, Warby, C.A, Labbe, P, Yang, C, Pflugrath, J.W, Ferrara, J.D, Robinson, H, Kushner, J.P, Hill, C.P. | | Deposit date: | 2004-06-08 | | Release date: | 2004-07-20 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of the Oxygen-dependant Coproporphyrinogen Oxidase (Hem13p) of Saccharomyces cerevisiae
J.Biol.Chem., 279, 2004
|
|
1R3V
 | | Uroporphyrinogen Decarboxylase single mutant D86E in complex with coproporphyrinogen-I | | Descriptor: | BETA-MERCAPTOETHANOL, COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1R3T
 | | Uroporphyrinogen Decarboxylase single mutant D86G in complex with coproporphyrinogen-III | | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1R3S
 | | Uroporphyrinogen Decarboxylase single mutant D86G in complex with coproporphyrinogen-I | | Descriptor: | COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1R3Q
 | | Uroporphyrinogen Decarboxylase in complex with coproporphyrinogen-I | | Descriptor: | CARBON DIOXIDE, COPROPORPHYRINOGEN I, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1R3R
 | |
2Q6Z
 | | Uroporphyrinogen Decarboxylase G168R single mutant apo-enzyme | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | | Deposit date: | 2007-06-05 | | Release date: | 2007-06-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Two novel uroporphyrinogen decarboxylase (URO-D) mutations causing hepatoerythropoietic porphyria (HEP).
Transl.Res., 149, 2007
|
|
2Q71
 | | Uroporphyrinogen Decarboxylase G168R single mutant enzyme in complex with coproporphyrinogen-III | | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Stadtmueller, B.M, Edwards, C.Q, Hill, C.P, Kushner, J.P. | | Deposit date: | 2007-06-05 | | Release date: | 2007-06-19 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Two Novel Uropophyrinogen Decarboxylase (URO-D) Mutations Causing Hepatoerythropoietic Porphyria (HEP)
Transl.Res., 149, 2007
|
|
1R3Y
 | | Uroporphyrinogen Decarboxylase in complex with coproporphyrinogen-III | | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.755 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1R3W
 | | Uroporphyrinogen Decarboxylase Y164F mutant in complex with coproporphyrinogen-III | | Descriptor: | COPROPORPHYRINOGEN III, Uroporphyrinogen Decarboxylase | | Authors: | Phillips, J.D, Whitby, F.G, Kushner, J.P, Hill, C.P. | | Deposit date: | 2003-10-03 | | Release date: | 2003-12-09 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural basis for tetrapyrrole coordination by uroporphyrinogen decarboxylase
Embo J., 22, 2003
|
|
1LC3
 | | Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex | | Descriptor: | Biliverdin Reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | | Authors: | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | | Deposit date: | 2002-04-05 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.
J.Mol.Biol., 319, 2002
|
|
3GVW
 | | Single-chain UROD F217Y (YF) mutation | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | Deposit date: | 2009-03-31 | | Release date: | 2009-12-22 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
|
|
3GVR
 | |
1LC0
 | | Structure of Biliverdin Reductase and the Enzyme-NADH Complex | | Descriptor: | Biliverdin Reductase A, PHOSPHATE ION | | Authors: | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | | Deposit date: | 2002-04-04 | | Release date: | 2002-07-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex.
J.Mol.Biol., 319, 2002
|
|
1NV8
 | | N5-glutamine methyltransferase, HemK | | Descriptor: | N5-METHYLGLUTAMINE, S-ADENOSYLMETHIONINE, hemK protein | | Authors: | Schubert, H.L, Phillips, J.D, Hill, C.P. | | Deposit date: | 2003-02-02 | | Release date: | 2003-05-27 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structures along the Catalytic Pathway of PrmC/HemK, an N(5)-Glutamine
AdoMet-Dependent Methyltransferase
Biochemistry, 42, 2003
|
|
3GW3
 | | human UROD mutant K297N | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | Deposit date: | 2009-03-31 | | Release date: | 2009-07-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases.
Cell Mol Biol (Noisy-le-grand), 55, 2009
|
|
3GVQ
 | | UROD single-chain dimer | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Hill, C.P, Phillips, J.D, Warby, C, Whitby, F.G, Kushner, J.P. | | Deposit date: | 2009-03-31 | | Release date: | 2009-07-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
|
|
3GW0
 | | UROD mutant G318R | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | Deposit date: | 2009-03-31 | | Release date: | 2009-07-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural and kinetic characterization of mutant human uroporphyrinogen decarboxylases.
Cell Mol Biol (Noisy-le-grand), 55, 2009
|
|
3GVV
 | | Single-chain UROD Y164G (GY) mutation | | Descriptor: | Uroporphyrinogen decarboxylase | | Authors: | Hill, C.P, Phillips, J.D, Whitby, F.G, Warby, C, Kushner, J.P. | | Deposit date: | 2009-03-31 | | Release date: | 2009-07-07 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Substrate shuttling between active sites of uroporphyrinogen decarboxylase is not required to generate coproporphyrinogen.
J.Mol.Biol., 389, 2009
|
|
1NV9
 | | HemK, apo structure | | Descriptor: | S-ADENOSYL-L-HOMOCYSTEINE, hemK protein | | Authors: | Schubert, H.L, Phillips, J.D, Hill, C.P. | | Deposit date: | 2003-02-02 | | Release date: | 2003-05-27 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (2.356 Å) | | Cite: | Structures along the Catalytic Pathway of PrmC/HemK, an N(5)-Glutamine
AdoMet-Dependent Methyltransferase
Biochemistry, 42, 2003
|
|
