5NSW
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![BU of 5nsw by Molmil](/molmil-images/mine/5nsw) | Xenon for tunnelling analysis of the efflux pump component OprN. | Descriptor: | Multidrug efflux outer membrane protein OprN, NICKEL (II) ION, PALMITIC ACID, ... | Authors: | Phan, G, Prange, T, Enguene Ntsogo, Y.V, Garnier, C, Ducruix, A, Broutin, I. | Deposit date: | 2017-04-27 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Xenon for tunnelling analysis of the efflux pump component OprN. PLoS ONE, 12, 2017
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3D5K
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3RFZ
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![BU of 3rfz by Molmil](/molmil-images/mine/3rfz) | Crystal structure of the FimD usher bound to its cognate FimC:FimH substrate | Descriptor: | Chaperone protein fimC, Outer membrane usher protein, type 1 fimbrial synthesis, ... | Authors: | Phan, G, Remaut, H, Lebedev, A, Geibel, S, Waksman, G. | Deposit date: | 2011-04-07 | Release date: | 2011-06-01 | Last modified: | 2012-03-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate. Nature, 474, 2011
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8Q8O
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5IUY
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![BU of 5iuy by Molmil](/molmil-images/mine/5iuy) | Structural insights of the outer-membrane channel OprN | Descriptor: | CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ... | Authors: | Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I. | Deposit date: | 2016-03-18 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Xenon for tunnelling analysis of the efflux pump component OprN. PLoS ONE, 12, 2017
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2XG5
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![BU of 2xg5 by Molmil](/molmil-images/mine/2xg5) | E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 5d | Descriptor: | (2R)-2-[5-CYCLOPROPYL-6-(HYDROXYSULFANYL)-4-(NAPHTHALEN-1-YLMETHYL)-2-OXOPYRIDIN-1(2H)-YL]-3-PHENYLPROPANOIC ACID, (2R,3R)-8-CYCLOPROPYL-7-(NAPHTHALEN-1-YLMETHYL)-5-OXO-2-PHENYL-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, CHAPERONE PROTEIN PAPD, ... | Authors: | Remaut, H, Phan, G, Buelens, F, Chorell, E, Pinkner, J.S, Edvinsson, S, Almqvist, F, Hultgren, S.J, Waksman, G. | Deposit date: | 2010-05-30 | Release date: | 2010-07-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity. J.Med.Chem., 53, 2010
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2XG4
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![BU of 2xg4 by Molmil](/molmil-images/mine/2xg4) | E. coli P pilus chaperone-subunit complex PapD-PapH bound to pilus biogenesis inhibitor, pilicide 2c | Descriptor: | (3R)-8-CYCLOPROPYL-6-(MORPHOLIN-4-YLMETHYL)-7-(1-NAPHTHYLMETHYL)-5-OXO-2,3-DIHYDRO-5H-[1,3]THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID, CHAPERONE PROTEIN PAPD, COBALT (II) ION, ... | Authors: | Remaut, H, Phan, G, Buelens, F, Chorell, E, Pinkner, J.S, Edvinsson, S, Almqvist, F, Hultgren, S.J, Waksman, G. | Deposit date: | 2010-05-30 | Release date: | 2010-07-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity. J.Med.Chem., 53, 2010
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6TA5
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![BU of 6ta5 by Molmil](/molmil-images/mine/6ta5) | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | Descriptor: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-29 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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6TA6
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![BU of 6ta6 by Molmil](/molmil-images/mine/6ta6) | MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs | Descriptor: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-29 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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6T7S
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![BU of 6t7s by Molmil](/molmil-images/mine/6t7s) | MexB structure solved by cryo-EM in nanodisc in absence of its protein partners | Descriptor: | Efflux pump membrane transporter | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-23 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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6ZRE
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![BU of 6zre by Molmil](/molmil-images/mine/6zre) | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Descriptor: | Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ... | Authors: | Ntsogo Enguene, Y.V, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I. | Deposit date: | 2020-07-13 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa. To Be Published
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4Y1K
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7AKZ
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![BU of 7akz by Molmil](/molmil-images/mine/7akz) | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Descriptor: | Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside | Authors: | Ntsogo Enguene, V.Y, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I. | Deposit date: | 2020-10-02 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa To Be Published
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2L1A
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![BU of 2l1a by Molmil](/molmil-images/mine/2l1a) | Solution NMR structure of the N-terminal GTPase-like domain of dictyostelium discoideum Fomin C | Descriptor: | Formin-C | Authors: | Dames, S.A, Schoenichen, A, Stephan, G, Geyer, M. | Deposit date: | 2010-07-27 | Release date: | 2011-08-17 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C. J.Biol.Chem., 286, 2011
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2C1J
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![BU of 2c1j by Molmil](/molmil-images/mine/2c1j) | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | Descriptor: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | Authors: | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | Deposit date: | 2005-09-15 | Release date: | 2005-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
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2C1N
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![BU of 2c1n by Molmil](/molmil-images/mine/2c1n) | Molecular basis for the recognition of phosphorylated and phosphoacetylated histone H3 by 14-3-3 | Descriptor: | 14-3-3 PROTEIN ZETA/DELTA, HISTONE H3 ACETYLPHOSPHOPEPTIDE | Authors: | Welburn, J.P.I, Macdonald, N, Noble, M.E.M, Nguyen, A, Yaffe, M.B, Clynes, D, Moggs, J.G, Orphanides, G, Thomson, S, Edmunds, J.W, Clayton, A.L, Endicott, J.A, Mahadevan, L.C. | Deposit date: | 2005-09-16 | Release date: | 2005-11-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular Basis for the Recognition of Phosphorylated and Phosphoacetylated Histone H3 by 14-3-3. Mol.Cell, 20, 2005
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