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PDB: 238 results

4K27
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BU of 4k27 by Molmil
Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
Descriptor: CHLORIDE ION, MAGNESIUM ION, Myotonic Dystrophy Type 2 RNA
Authors:Park, H, Lohman, J, Disney, M.D.
Deposit date:2013-04-08
Release date:2013-11-27
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Myotonic Dystrophy Type 2 RNA: Structural Studies and Designed Small Molecules that Modulate RNA Function
ACS CHEM.BIOL., 2013
6BAN
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BU of 6ban by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
Descriptor: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain R11 Heavy chain, Variable domain of R11 Light Chain
Authors:Park, H, Rader, C.
Deposit date:2017-10-14
Release date:2018-06-13
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
3V6R
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BU of 3v6r by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, LoGrasso, P.V, Laughlin, J.D.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3V6S
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BU of 3v6s by Molmil
Discovery of potent and selective covalent inhibitors of JNK
Descriptor: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, Laughlin, J.D, LoGrasso, P.V.
Deposit date:2011-12-20
Release date:2012-02-01
Last modified:2012-07-25
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
1YPU
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BU of 1ypu by Molmil
Human Oxidized Low Density Lipoprotein Receptor LOX-1 C2 Space Group
Descriptor: oxidised low density lipoprotein (lectin-like) receptor 1
Authors:Park, H, Adsit, F.G, Boyington, J.C.
Deposit date:2005-01-31
Release date:2005-02-08
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.
J.Biol.Chem., 280, 2005
1YPO
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BU of 1ypo by Molmil
Human Oxidized Low Density Lipoprotein Receptor LOX-1 P3 1 21 Space Group
Descriptor: oxidised low density lipoprotein (lectin-like) receptor 1
Authors:Park, H, Adsit, F.G, Boyington, J.C.
Deposit date:2005-01-31
Release date:2005-02-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.
J.Biol.Chem., 280, 2005
1YPQ
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BU of 1ypq by Molmil
Human Oxidized Low Density Lipoprotein Receptor LOX-1 Dioxane Complex
Descriptor: 1,4-DIETHYLENE DIOXIDE, oxidised low density lipoprotein (lectin-like) receptor 1
Authors:Park, H, Adsit, F.G, Boyington, J.C.
Deposit date:2005-01-31
Release date:2005-02-08
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.
J.Biol.Chem., 280, 2005
5BTM
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BU of 5btm by Molmil
Crystal structure of AUUCU repeating RNA that causes spinocerebellar ataxia type 10 (SCA10)
Descriptor: MAGNESIUM ION, RNA (55-mer), SODIUM ION
Authors:Park, H.
Deposit date:2015-06-03
Release date:2015-07-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.778 Å)
Cite:Crystallographic and Computational Analyses of AUUCU Repeating RNA That Causes Spinocerebellar Ataxia Type 10 (SCA10).
Biochemistry, 54, 2015
7TUS
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BU of 7tus by Molmil
Sculpting a uniquely reactive cysteine residue for site-specific antibody conjugation
Descriptor: Antibody Heavy Chain, Antibody Light Chain, DI(HYDROXYETHYL)ETHER, ...
Authors:Park, H, Rader, C.
Deposit date:2022-02-03
Release date:2022-06-08
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Sculpting a Uniquely Reactive Cysteine Residue for Site-Specific Antibody Conjugation.
Bioconjug.Chem., 33, 2022
1N4E
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BU of 1n4e by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Descriptor: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3'
Authors:Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C.
Deposit date:2002-10-30
Release date:2003-02-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DNA decamer containing a cis-syn thymine dimer.
Proc.Natl.Acad.Sci.USA, 99, 2002
6AVK
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BU of 6avk by Molmil
Streptavidin bound to peptide-like compound KPM-6
Descriptor: 1-hydroxydodecan-4-one, N-[(2H-1,3-benzodioxol-5-yl)methyl]-2-({[(2H-1,3-benzodioxol-5-yl)methyl][2-(chloromethyl)-1,3-oxazole-4-carbonyl]amino}methyl)-N-[(4-carbamoyl-1,3-oxazol-2-yl)methyl]-1,3-oxazole-4-carboxamide, Streptavidin
Authors:Park, H, Shamim, R, McEnaney, P, Kodadek, T.
Deposit date:2017-09-02
Release date:2018-08-08
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Efficient Workflow for Screening DNA-encoded One Bead One Compound Libraries Using a Flow Cytometer
To be Published
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
Descriptor: CACODYLATE ION, Invasin ipaA, Vinculin
Authors:Park, H, Sharff, A, Izard, T.
Deposit date:2011-04-05
Release date:2011-04-27
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
3TJ6
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BU of 3tj6 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
Descriptor: Antigenic heat-stable 120 kDa protein, Vinculin
Authors:Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
Deposit date:2011-08-23
Release date:2011-09-07
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
6N2U
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BU of 6n2u by Molmil
IL-8 Structure from Bacterial Expression Source
Descriptor: Interleukin-8
Authors:Park, H, Jung, J.H, Luo, J.L.
Deposit date:2018-11-14
Release date:2019-11-20
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.254 Å)
Cite:IL-8 Structure from Bacterial Expression Source
To Be Published
1SM5
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BU of 1sm5 by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Descriptor: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*(BRU)P*TP*AP*AP*TP*(BRU)P*CP*G)-3'
Authors:Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C.
Deposit date:2004-03-08
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
1T4I
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BU of 1t4i by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Descriptor: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3'
Authors:Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C.
Deposit date:2004-04-29
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
1BXD
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BU of 1bxd by Molmil
NMR STRUCTURE OF THE HISTIDINE KINASE DOMAIN OF THE E. COLI OSMOSENSOR ENVZ
Descriptor: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PROTEIN (OSMOLARITY SENSOR PROTEIN (ENVZ))
Authors:Tanaka, T, Saha, S.K, Tomomori, C, Ishima, R, Liu, D, Tong, K.I, Park, H, Dutta, R, Qin, L, Swindells, M.B, Yamazaki, T, Ono, A.M, Kainosho, M, Inouye, M, Ikura, M.
Deposit date:1998-10-02
Release date:1999-10-02
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:NMR structure of the histidine kinase domain of the E. coli osmosensor EnvZ.
Nature, 396, 1998
3CEQ
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BU of 3ceq by Molmil
The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
Descriptor: Kinesin light chain 2
Authors:Zhu, H, Shen, Y, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-02-29
Release date:2008-08-12
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:The TPR domain of Human Kinesin Light Chain 2 (hKLC2)
To be Published
3LJ8
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BU of 3lj8 by Molmil
Crystal Structure of MKP-4
Descriptor: Tyrosine-protein phosphatase
Authors:Jeong, D.G, Yoon, T.S, Jung, S.-K, Park, H.S, Ryu, S.E, Kim, S.J.
Deposit date:2010-01-26
Release date:2010-12-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Exploring binding sites other than the catalytic core in the crystal structure of the catalytic domain of MKP-4
Acta Crystallogr.,Sect.D, 67, 2011
3CXL
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BU of 3cxl by Molmil
Crystal structure of human chimerin 1 (CHN1)
Descriptor: N-chimerin, UNKNOWN ATOM OR ION, ZINC ION
Authors:Shen, L, Buck, M, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Wilkstrom, M, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-04-24
Release date:2008-08-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human chimerin 1 (CHN1).
To be Published
3CON
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BU of 3con by Molmil
Crystal structure of the human NRAS GTPase bound with GDP
Descriptor: GTPase NRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Nedyalkova, L, Tong, Y, Tempel, W, Shen, L, Loppnau, P, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2008-03-28
Release date:2008-04-08
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Crystal structure of the human NRAS GTPase bound with GDP.
To be Published
3V70
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BU of 3v70 by Molmil
Crystal Structure of Human GTPase IMAP family member 1
Descriptor: GTPase IMAP family member 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Nedyalkova, L, Shen, Y, Tong, Y, Tempel, W, Mackenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Andrews, D.W, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2011-12-20
Release date:2012-01-11
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Crystal Structure of Human GTPase IMAP family member 1
to be published
3LJU
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BU of 3lju by Molmil
Crystal structure of full length centaurin alpha-1 bound with the head group of PIP3
Descriptor: (2R)-3-{[(R)-{[(1S,2S,3R,4S,5S,6S)-2,6-dihydroxy-3,4,5-tris(phosphonooxy)cyclohexyl]oxy}(hydroxy)phosphoryl]oxy}propane -1,2-diyl dioctanoate, Arf-GAP with dual PH domain-containing protein 1, ZINC ION
Authors:Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
Deposit date:2010-01-26
Release date:2010-11-24
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin alpha1.
Proc.Natl.Acad.Sci.USA, 107, 2010
5UMB
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BU of 5umb by Molmil
Crystal structure of ATPase domain of Malaria GRP78 with ADP bound
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Chaperone DnaK, MAGNESIUM ION, ...
Authors:Chen, Y, Antoshchenko, T, Pizarro, J.C, Song, J.H, Park, H.
Deposit date:2017-01-26
Release date:2022-07-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Repurposing drugs to target the malaria parasite unfolding protein response.
Sci Rep, 8, 2018

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