3CON
Crystal structure of the human NRAS GTPase bound with GDP
Summary for 3CON
Entry DOI | 10.2210/pdb3con/pdb |
Descriptor | GTPase NRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total) |
Functional Keywords | structural genomics consortium, sgc, gtpase, gdp, oncogene, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane ; Lipid-anchor ; Cytoplasmic side : P01111 |
Total number of polymer chains | 1 |
Total formula weight | 22312.04 |
Authors | Nedyalkova, L.,Tong, Y.,Tempel, W.,Shen, L.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.,Structural Genomics Consortium (SGC) (deposition date: 2008-03-28, release date: 2008-04-08, Last modification date: 2023-08-30) |
Primary citation | Nedyalkova, L.,Tong, Y.,Tempel, W.,Shen, L.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H. Crystal structure of the human NRAS GTPase bound with GDP. To be Published, |
Experimental method | X-RAY DIFFRACTION (1.649 Å) |
Structure validation
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