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3CON

Crystal structure of the human NRAS GTPase bound with GDP

Summary for 3CON
Entry DOI10.2210/pdb3con/pdb
DescriptorGTPase NRas, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
Functional Keywordsstructural genomics consortium, sgc, gtpase, gdp, oncogene, disease mutation, golgi apparatus, gtp-binding, lipoprotein, membrane, methylation, nucleotide-binding, palmitate, prenylation, proto-oncogene, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCell membrane ; Lipid-anchor ; Cytoplasmic side : P01111
Total number of polymer chains1
Total formula weight22312.04
Authors
Primary citationNedyalkova, L.,Tong, Y.,Tempel, W.,Shen, L.,Loppnau, P.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Weigelt, J.,Bochkarev, A.,Park, H.
Crystal structure of the human NRAS GTPase bound with GDP.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.649 Å)
Structure validation

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PDB entries from 2024-10-30

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