Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 414 results

1SJI
DownloadVisualize
BU of 1sji by Molmil
Comparing skeletal and cardiac calsequestrin structures and their calcium binding: a proposed mechanism for coupled calcium binding and protein polymerization
Descriptor: Calsequestrin, cardiac muscle isoform
Authors:Park, H.J, Park, I.Y, Kim, E.J, Youn, B, Fields, K, Dunker, A.K, Kang, C.H.
Deposit date:2004-03-03
Release date:2005-03-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Comparing skeletal and cardiac calsequestrin structures and their calcium binding: a proposed mechanism for coupled calcium binding and protein polymerization.
J.Biol.Chem., 279, 2004
7YPC
DownloadVisualize
BU of 7ypc by Molmil
Notothenia coriiceps TRAF4
Descriptor: TNF receptor-associated factor
Authors:Park, H.H, Kim, C.M, Jang, H.S.
Deposit date:2022-08-03
Release date:2023-07-12
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structure of fish TRAF4 and its implication in TRAF4-mediated immune cell and platelet signaling.
Fish Shellfish Immunol., 132, 2023
4W4X
DownloadVisualize
BU of 4w4x by Molmil
JNK2/3 in complex with 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Descriptor: 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-jun NH2-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
1S67
DownloadVisualize
BU of 1s67 by Molmil
Crystal structure of heme domain of direct oxygen sensor from E. coli
Descriptor: Hypothetical protein yddU, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Park, H.J, Suquet, C, Satterlee, J.D, Kang, C.H.
Deposit date:2004-01-22
Release date:2004-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Insights into signal transduction involving PAS domain oxygen-sensing heme proteins from the X-ray crystal structure of Escherichia coli Dos heme domain (Ec DosH)
Biochemistry, 43, 2004
1S66
DownloadVisualize
BU of 1s66 by Molmil
Crystal structure of heme domain of direct oxygen sensor from E. coli
Descriptor: Hypothetical protein yddU, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Park, H.J, Suquet, C, Satterlee, J.D, Kang, C.H.
Deposit date:2004-01-22
Release date:2004-06-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Insights into signal transduction involving PAS domain oxygen-sensing heme proteins from the X-ray crystal structure of Escherichia coli Dos heme domain (Ec DosH)
Biochemistry, 43, 2004
1SM5
DownloadVisualize
BU of 1sm5 by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Descriptor: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*(BRU)P*TP*AP*AP*TP*(BRU)P*CP*G)-3'
Authors:Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.-S, Kang, C.
Deposit date:2004-03-08
Release date:2004-05-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structure of a DNA Decamer Containing a Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
1DNP
DownloadVisualize
BU of 1dnp by Molmil
STRUCTURE OF DEOXYRIBODIPYRIMIDINE PHOTOLYASE
Descriptor: 5,10-METHENYL-6,7,8-TRIHYDROFOLIC ACID, DNA PHOTOLYASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Park, H.-W, Sancar, A, Deisenhofer, J.
Deposit date:1995-07-03
Release date:1996-08-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of DNA photolyase from Escherichia coli.
Science, 268, 1995
4W4V
DownloadVisualize
BU of 4w4v by Molmil
JNK2/3 in complex with 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Descriptor: 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-Jun N-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4W4Y
DownloadVisualize
BU of 4w4y by Molmil
JNK2/3 in complex with 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Descriptor: 3-(4-{[(4-methylphenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide, c-jun NH2-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4W4W
DownloadVisualize
BU of 4w4w by Molmil
JNK2/3 in complex with N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide
Descriptor: N-(2-methylpyridin-4-yl)-3-{4-[(phenylcarbamoyl)amino]-1H-pyrazol-1-yl}benzamide, c-Jun N-terminal kinase 3
Authors:Park, H, Iqbal, S, Hernandez, P, Mora, R, Zheng, K, Feng, Y, LoGrasso, P.
Deposit date:2014-08-15
Release date:2015-02-11
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles.
Sci Rep, 5, 2015
4WHZ
DownloadVisualize
BU of 4whz by Molmil
Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives
Descriptor: 3-(4-{[(2-chlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-{1-[(3S)-pyrrolidin-3-yl]-1H-pyrazol-4-yl}benzamide, Mitogen-activated protein kinase 10
Authors:Park, H, LoGrasso, P.
Deposit date:2014-09-24
Release date:2014-11-26
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Design and Synthesis of Highly Potent and Isoform Selective JNK3 Inhibitors: SAR Studies on Aminopyrazole Derivatives.
J.Med.Chem., 57, 2014
5ZYN
DownloadVisualize
BU of 5zyn by Molmil
Fumarate reductase
Descriptor: FLAVIN MONONUCLEOTIDE, FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase 2, ...
Authors:Park, H.H, Kim, C.M.
Deposit date:2018-05-25
Release date:2018-10-03
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
Nat Commun, 9, 2018
5ZTX
DownloadVisualize
BU of 5ztx by Molmil
co-factor free Transaminase
Descriptor: 1,2-ETHANEDIOL, transaminase
Authors:Park, H.H, Shin, Y.C.
Deposit date:2018-05-05
Release date:2018-08-29
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural dynamics of the transaminase active site revealed by the crystal structure of a co-factor free omega-transaminase from Vibrio fluvialis JS17
Sci Rep, 8, 2018
8ENJ
DownloadVisualize
BU of 8enj by Molmil
Design, synthesis, biological evaluation, and X-ray crystallography of diarylpyrazole derivatives possessing terminal arylsulfonamide moieties as anti-proliferative agents targeting c-Jun N-terminal kinase (JNK)
Descriptor: Mitogen-activated protein kinase 10, N-[3-({(4P)-4-[(3M)-1-tert-butyl-3-(3-hydroxyphenyl)-1H-pyrazol-4-yl]pyridin-2-yl}amino)propyl]-4-hydroxybenzene-1-sulfonamide
Authors:Park, H, Mersal, K.I.
Deposit date:2022-09-30
Release date:2023-10-18
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Evaluation of novel pyrazol-4-yl pyridine derivatives possessing arylsulfonamide tethers as c-Jun N-terminal kinase (JNK) inhibitors in leukemia cells.
Eur.J.Med.Chem., 261, 2023
6AGW
DownloadVisualize
BU of 6agw by Molmil
Pro-domain of Caspase-8
Descriptor: Caspase-8 pro-domain
Authors:Park, H.H.
Deposit date:2018-08-15
Release date:2019-06-26
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.093 Å)
Cite:Molecular basis of dimerization of initiator caspase was revealed by crystal structure of caspase-8 pro-domain.
Cell Death Differ., 26, 2019
9B1R
DownloadVisualize
BU of 9b1r by Molmil
Functional implication of the homotrimeric multidomain vacuolar sorting receptor 1 from Arabidopsis thaliana
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Vacuolar-sorting receptor 1
Authors:Park, H, Youn, B, Park, D.J, Puthanveettil, S.V, Kang, C.
Deposit date:2024-03-13
Release date:2024-05-15
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Functional implication of the homotrimeric multidomain vacuolar sorting receptor 1 (VSR1) from Arabidopsis thaliana.
Sci Rep, 14, 2024
7S1N
DownloadVisualize
BU of 7s1n by Molmil
N-Aromatic-Substituted Indazole Derivatives as Brain Penetrant and Orally Bioavailable JNK3 Inhibitors
Descriptor: 4-[5-(2-chloro-6-fluoroanilino)-6-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl]-N-(oxetan-3-yl)thiophene-2-carboxamide, Mitogen-activated protein kinase 10
Authors:Park, H.
Deposit date:2021-09-02
Release date:2021-11-03
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:N -Aromatic-Substituted Indazole Derivatives as Brain-Penetrant and Orally Bioavailable JNK3 Inhibitors.
Acs Med.Chem.Lett., 12, 2021
6DZR
DownloadVisualize
BU of 6dzr by Molmil
Crystal structure of h38C2 K99R mutation
Descriptor: CITRATE ANION, SULFATE ION, h38c2 heavy chain, ...
Authors:Park, H, Rader, C.
Deposit date:2018-07-05
Release date:2019-07-10
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues.
Cell Chem Biol, 26, 2019
7VPF
DownloadVisualize
BU of 7vpf by Molmil
Crystal structure of a novel putative sugar isomerase from the psychrophilic bacterium Paenibacillus sp. R4
Descriptor: CALCIUM ION, Xylose isomerase, ZINC ION
Authors:Park, H.H, Lee, J.H, Kwon, S.
Deposit date:2021-10-16
Release date:2021-12-29
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.983 Å)
Cite:Crystal structure of a novel putative sugar isomerase from the psychrophilic bacterium Paenibacillus sp. R4.
Biochem.Biophys.Res.Commun., 585, 2021
1RF6
DownloadVisualize
BU of 1rf6 by Molmil
Structural Studies of Streptococcus pneumoniae EPSP Synthase in S3P-GLP Bound State
Descriptor: 5-enolpyruvylshikimate-3-phosphate synthase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE
Authors:Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C.
Deposit date:2003-11-07
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
1RF4
DownloadVisualize
BU of 1rf4 by Molmil
Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State
Descriptor: (3R,4S,5R)-5-{[(1R)-1-CARBOXY-2-FLUORO-1-(PHOSPHONOOXY)ETHYL]OXY}-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 5-enolpyruvylshikimate-3-phosphate synthase
Authors:Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C.
Deposit date:2003-11-07
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
1RF5
DownloadVisualize
BU of 1rf5 by Molmil
Structural Studies of Streptococcus pneumoniae EPSP Synthase in Unliganded State
Descriptor: 5-enolpyruvylshikimate-3-phosphate synthase
Authors:Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C.
Deposit date:2003-11-07
Release date:2004-02-17
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
8EFJ
DownloadVisualize
BU of 8efj by Molmil
A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds
Descriptor: (4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside
Authors:Park, H, Feng, Y.
Deposit date:2022-09-08
Release date:2023-09-20
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds
To Be Published
6BA5
DownloadVisualize
BU of 6ba5 by Molmil
Potent and Selective Antitumor Activity of a T-Cell Engaging Bispecific Antibody Targeting a Membrane-Proximal Epitope of ROR1
Descriptor: Inactive tyrosine-protein kinase transmembrane receptor ROR1, Variable domain Heavy chain, antibody R11, ...
Authors:Park, H, Rader, C.
Deposit date:2017-10-12
Release date:2018-06-13
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6U85
DownloadVisualize
BU of 6u85 by Molmil
Site-specific lysine arylation as an alternative bioconjugation strategy for chemically programmed antibodies and antibody-drug conjugates
Descriptor: Antibody Fab heavy chain, GLYCEROL, antibody Fab Light chain
Authors:Park, H, Rader, C.
Deposit date:2019-09-04
Release date:2019-11-13
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.78 Å)
Cite:Site-Specific Lysine Arylation as an Alternative Bioconjugation Strategy for Chemically Programmed Antibodies and Antibody-Drug Conjugates.
Bioconjug.Chem., 30, 2019

226262

건을2024-10-16부터공개중

PDB statisticsPDBj update infoContact PDBjnumon