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PDB: 414 件
3V6R
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BU of 3v6r by Molmil
Discovery of potent and selective covalent inhibitors of JNK
分子名称: 4-{[4-(dimethylamino)butanoyl]amino}-N-(3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
著者Park, H, LoGrasso, P.V, Laughlin, J.D.
登録日2011-12-20
公開日2012-02-01
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
3V6S
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BU of 3v6s by Molmil
Discovery of potent and selective covalent inhibitors of JNK
分子名称: 3-{[4-(dimethylamino)butanoyl]amino}-N-(4-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide, Mitogen-activated protein kinase 10
著者Park, H, Laughlin, J.D, LoGrasso, P.V.
登録日2011-12-20
公開日2012-02-01
最終更新日2012-07-25
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Discovery of potent and selective covalent inhibitors of JNK.
Chem.Biol., 19, 2012
5GLG
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BU of 5glg by Molmil
The novel function of Osm1 under anaerobic condition in the ER was revealed by crystal structure of Osm1, a soluble fumarate reductase in yeast
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase 2, SUCCINIC ACID
著者Park, H.H, Choi, J.Y.
登録日2016-07-11
公開日2017-07-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular basis of maintaining an oxidizing environment under anaerobiosis by soluble fumarate reductase.
Nat Commun, 9, 2018
3QF2
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BU of 3qf2 by Molmil
Crystal structure of NALP3 PYD
分子名称: NACHT, LRR and PYD domains-containing protein 3
著者Park, H.H, Bae, J.Y.
登録日2011-01-21
公開日2011-08-31
最終更新日2011-11-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of NALP3 Protein Pyrin Domain (PYD) and Its Implications in Inflammasome Assembly
J.Biol.Chem., 286, 2011
3RF3
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BU of 3rf3 by Molmil
Shigella IpaA-VBS3 in complex with human vinculin
分子名称: CACODYLATE ION, Invasin ipaA, Vinculin
著者Park, H, Sharff, A, Izard, T.
登録日2011-04-05
公開日2011-04-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Novel vinculin binding site of the IpaA invasin of Shigella.
J.Biol.Chem., 286, 2011
7XHZ
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BU of 7xhz by Molmil
Crystal structure of SAV2152 from MRSA
分子名称: Phosphatase, SAV2152
著者Park, H.J, Seok, S.H, Kim, J.H.
登録日2022-04-11
公開日2023-04-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structure of SAV2152 from MRSA
To Be Published
3TJ5
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BU of 3tj5 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-N; residues 412-434) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, GLYCEROL, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
6N2U
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BU of 6n2u by Molmil
IL-8 Structure from Bacterial Expression Source
分子名称: Interleukin-8
著者Park, H, Jung, J.H, Luo, J.L.
登録日2018-11-14
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.254 Å)
主引用文献IL-8 Structure from Bacterial Expression Source
To Be Published
3TJ6
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BU of 3tj6 by Molmil
human vinculin head domain (Vh1, residues 1-258) in complex with the vinculin binding site of the surface cell antigen 4 (sca4-VBS-C; residues 812-835) from Rickettsia rickettsii
分子名称: Antigenic heat-stable 120 kDa protein, Vinculin
著者Park, H, Lee, J.H, Gouin, E, Cossart, P, Izard, T.
登録日2011-08-23
公開日2011-09-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin.
J.Biol.Chem., 286, 2011
7BR9
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BU of 7br9 by Molmil
Crystal structure of mus musculus IRG1
分子名称: Cis-aconitate decarboxylase
著者Park, H.H, Chun, H.L.
登録日2020-03-27
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The crystal structure of mouse IRG1 suggests that cis-aconitate decarboxylase has an open and closed conformation.
Plos One, 15, 2020
7D1I
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BU of 7d1i by Molmil
Crystal structure of acinetobacter baumannii MurG
分子名称: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
著者Park, H.H, Jeong, k.H.
登録日2020-09-14
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.487 Å)
主引用文献Putative hexameric glycosyltransferase functional unit revealed by the crystal structure of Acinetobacter baumannii MurG
Iucrj, 8, 2021
7D27
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Structure of UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase
分子名称: UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase
著者Park, H.H, Jeong, K.H.
登録日2020-09-16
公開日2021-07-28
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Wide-open conformation of UDP-MurNc-tripeptide ligase revealed by the substrate-free structure of MurE from Acinetobacter baumannii.
Febs Lett., 595, 2021
7BRA
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BU of 7bra by Molmil
Bacillus subtilis IRG1
分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, Bacillus subtilis IRG1, SULFATE ION
著者Park, H.H, Chun, H.L.
登録日2020-03-27
公開日2021-02-03
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.785 Å)
主引用文献Enzymatic reaction mechanism of cis-aconitate decarboxylase based on the crystal structure of IRG1 from Bacillus subtilis.
Sci Rep, 10, 2020
1T4I
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BU of 1t4i by Molmil
Crystal Structure of a DNA Decamer Containing a Thymine-dimer
分子名称: 5'-D(*CP*GP*AP*AP*TP*TP*AP*AP*GP*C)-3', 5'-D(*GP*CP*TP*TP*AP*AP*TP*TP*CP*G)-3'
著者Park, H, Zhang, K, Ren, Y, Nadji, S, Sinha, N, Taylor, J.S, Kang, C.
登録日2004-04-29
公開日2004-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of a DNA Decamer Containing a cis-syn Thymine-dimer
Proc.Natl.Acad.Sci.USA, 99, 2002
7BSO
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BU of 7bso by Molmil
Crystal structure of the human NLRP9 pyrin domain
分子名称: NACHT, LRR and PYD domains-containing protein 9
著者Park, H.H, Ha, H.J.
登録日2020-03-31
公開日2021-02-10
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Crystal structure of the human NLRP9 pyrin domain reveals a bent N-terminal loop that may regulate inflammasome assembly.
Febs Lett., 594, 2020
7E52
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BU of 7e52 by Molmil
Acinetobacter baumannii Thioredoxin reductase
分子名称: Thioredoxin reductase
著者Park, H.H, Chun, H.L.
登録日2021-02-16
公開日2022-02-23
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Acinetobacter baumannii Thioredoxin reductase
To Be Published
5XPC
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BU of 5xpc by Molmil
Crystal Structure of Drep4 CIDE domain
分子名称: DNAation factor-related protein 4, GLYCEROL
著者Park, H.H, Jeong, J.H.
登録日2017-06-01
公開日2017-07-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.902 Å)
主引用文献CIDE domains form functionally important higher-order assemblies for DNA fragmentation.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5XPB
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BU of 5xpb by Molmil
Crystal Structure of Selenomethionine labelled Drep4 CIDE domain
分子名称: DNAation factor-related protein 4
著者Park, H.H, Jeong, J.H.
登録日2017-06-01
公開日2018-06-20
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Crystal Structure of Selenomethionine labelled Drep4 CIDE domain
To Be Published
5YC1
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BU of 5yc1 by Molmil
TRAF4_GPIb complex
分子名称: GPIb peptide, TNF receptor-associated factor 4
著者Park, H.H, Kim, C.M.
登録日2017-09-06
公開日2017-10-11
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.506 Å)
主引用文献Molecular basis for unique specificity of human TRAF4 for platelets GPIb beta and GPVI
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W3D
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BU of 5w3d by Molmil
The structure of kinesin-14 wild-type Ncd-ADP dimer
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Protein claret segregational
著者Park, H.W, Ma, Z, Chacko, J, Jiang, S.M, Robinson, R.C, Endow, S.A.
登録日2017-06-07
公開日2017-12-20
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein.
Sci Rep, 7, 2017
2MCY
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BU of 2mcy by Molmil
CR1 Sushi domains 2 and 3
分子名称: Complement receptor type 1
著者Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2014-01-22
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2MCZ
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BU of 2mcz by Molmil
CR1 Sushi domains 1 and 2
分子名称: Complement receptor type 1
著者Park, H.J, Guariento, M.J, Maciejewski, M, Hauart, R, Tham, W, Cowman, A.F, Schmidt, C.Q, Martens, H, Liszewski, K.M, Hourcade, D, Barlow, P.N, Atkinson, J.P.
登録日2013-08-27
公開日2013-11-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Using Mutagenesis and Structural Biology to Map the Binding Site for the Plasmodium falciparum Merozoite Protein PfRh4 on the Human Immune Adherence Receptor.
J.Biol.Chem., 289, 2014
2OF5
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BU of 2of5 by Molmil
Oligomeric Death Domain complex
分子名称: Death domain-containing protein CRADD, Leucine-rich repeat and death domain-containing protein
著者Park, H.H, Logette, E, Raunser, S, Cuenin, S, Walz, T, Tschopp, J, Wu, H.
登録日2007-01-02
公開日2007-04-17
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Death domain assembly mechanism revealed by crystal structure of the oligomeric PIDDosome core complex.
Cell(Cambridge,Mass.), 128, 2007
8HJJ
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BU of 8hjj by Molmil
Anti-CRISPR protein AcrIC9
分子名称: Anti-CRISPR protein Type I-C9
著者Kang, Y.J, Park, H.H.
登録日2022-11-23
公開日2023-09-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The structure of AcrIC9 revealing the putative inhibitory mechanism of AcrIC9 against the type IC CRISPR-Cas system.
Iucrj, 10, 2023
3CPF
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BU of 3cpf by Molmil
Crystal structure of human eukaryotic translation initiation factor EIF5A
分子名称: Eukaryotic translation initiation factor 5A-1, UNKNOWN ATOM OR ION
著者Nedyalkova, L, Tong, Y, Tempel, W, Hong, B, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2008-03-31
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human eIF5A1: insight into functional similarity of human eIF5A1 and eIF5A2.
Proteins, 75, 2009

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