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PDB: 99 results

5HVV
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Crystal structure of Pro1 deletion and M2A double mutant of Macrophage Migration Inhibitory Factor
Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION
Authors:Pantouris, G, Lolis, E.
Deposit date:2016-01-28
Release date:2016-02-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of P1 deletion and M2A double mutant of Macrophage Migration Inhibitory Factor
To Be Published
4PLU
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Crystal structure of Macrophage Migration Inhibitory Factor in complex with benzaldehyde
Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2014-05-19
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4PKZ
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Crystal structure of P1M mutant of Macrophage Migration Inhibitory Factor
Descriptor: ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, SULFATE ION
Authors:Pantouris, G, Lolis, E.
Deposit date:2014-05-15
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4PKK
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BU of 4pkk by Molmil
Crystal structure of Macrophage Migration inhibitory factor in complex with furan-2-ylmethyl)imino methanethiol
Descriptor: (Z)-[(furan-2-ylmethyl)imino]methanethiol, GLYCEROL, ISOPROPYL ALCOHOL, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2014-05-14
Release date:2016-05-04
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of Macrophage Migration inhibitory factor with a covalent inhibitor
To Be Published
6OYB
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BU of 6oyb by Molmil
Crystal structure of H62G mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2019-05-14
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel.
Cell Chem Biol, 27, 2020
6OYE
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Crystal structure of Y99F mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2019-05-14
Release date:2020-04-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel.
Cell Chem Biol, 27, 2020
6OYG
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BU of 6oyg by Molmil
Crystal structure of H62F mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2019-05-14
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel.
Cell Chem Biol, 27, 2020
6OY8
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BU of 6oy8 by Molmil
Crystal structure of Y99G mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2019-05-14
Release date:2020-04-22
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Regulation of MIF Enzymatic Activity by an Allosteric Site at the Central Solvent Channel.
Cell Chem Biol, 27, 2020
8SPN
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BU of 8spn by Molmil
Crystal structure of macrophage migration inhibitory factor in complex with T614
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Iguratimod, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2023-05-03
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose.
Mol Med, 30, 2024
8SON
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BU of 8son by Molmil
Crystal structure of macrophage migration inhibitory factor in complex with N-[3-(Trifluoromethyl)phenyl]-3-(2-chloroanilino)-2-cyano-3-thioxopropanamide
Descriptor: (2R)-3-[(2-chlorophenyl)amino]-2-cyano-3-thioxo-N-[3-(trifluoromethyl)phenyl]propanamide, GLYCEROL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2023-04-28
Release date:2024-05-22
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Crystal structure of the macrophage migration inhibitory factor in complex with N-[3-(Trifluoromethyl)phenyl]-3-(2-chloroanilino)-2-cyano-3-thioxopropanamide
To Be Published
4TRF
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BU of 4trf by Molmil
Crystal structure of Macrophage Migration Inhibitory Factor in complex with N-(pyridin-3-ylmethyl)thioformamide
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2014-06-16
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4TRU
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BU of 4tru by Molmil
Crystal structure of Q24A Q25A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2014-06-17
Release date:2015-09-30
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
6BG7
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BU of 6bg7 by Molmil
Crystal structure of G107A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2017-10-27
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
6BG6
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BU of 6bg6 by Molmil
Crystal structure of S111A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2017-10-27
Release date:2018-06-06
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Angew. Chem. Int. Ed. Engl., 57, 2018
6XV5
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BU of 6xv5 by Molmil
Crystal structure of penicillin-binding protein 2 from Yersinia pestis in complex with ertapenem
Descriptor: L(+)-TARTARIC ACID, Peptidoglycan D,D-transpeptidase MrdA
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2020-01-21
Release date:2021-02-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.673 Å)
Cite:The structure of penicillin-binding protein 2 from Yersinia pestis
To Be Published
6C5F
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BU of 6c5f by Molmil
Human D-Dopachrome tautomerase (D-DT)/ macrophage migration inhibitory factor 2 (MIF2) complexed with the selective inhibitor 4-CPPC
Descriptor: 4-(3-carboxyphenyl)pyridine-2,5-dicarboxylic acid, D-dopachrome decarboxylase
Authors:Pantouris, G, Lolis, E.J.
Deposit date:2018-01-16
Release date:2018-06-13
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural Plasticity in the C-Terminal Region of Macrophage Migration Inhibitory Factor-2 Is Associated with an Induced Fit Mechanism for a Selective Inhibitor.
Biochemistry, 57, 2018
2HQ8
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BU of 2hq8 by Molmil
Crystal structure of coelenterazine-binding protein from renilla muelleri in the ca loaded apo form
Descriptor: CALCIUM ION, Coelenterazine-binding protein ca-bound apo form
Authors:Stepanyuk, G, Liu, Z.J, Vysotski, E.S, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-07-18
Release date:2006-09-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of coelenterazine-binding protein from Renilla muelleri at 1.7 A: why it is not a calcium-regulated photoprotein.
PHOTOCHEM.PHOTOBIOL.SCI., 7, 2008
6SYN
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BU of 6syn by Molmil
Crystal structure of Y. pestis penicillin-binding protein 3
Descriptor: (2R,4S)-2-[(1R)-1-{[(2S)-2-carboxy-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, ACETATE ION, Peptidoglycan D,D-transpeptidase FtsI
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2019-09-30
Release date:2020-10-14
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.63 Å)
Cite:The structure of penicillin-binding protein 3 from Yersinia pestis
To Be Published
6TII
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BU of 6tii by Molmil
Crystal structure of penicillin-binding protein 2 from Yersinia pestis
Descriptor: BROMIDE ION, Peptidoglycan D,D-transpeptidase MrdA
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2019-11-22
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:The structure of penicillin-binding protein 2 from Yersinia pestis
To Be Published
6TUD
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BU of 6tud by Molmil
Crystal structure of Y. pestis penicillin-binding protein 3
Descriptor: Peptidoglycan D,D-transpeptidase FtsI
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2020-01-06
Release date:2021-01-27
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structure of penicillin-binding protein 3 from Yersinia pestis
To Be Published
6TIX
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BU of 6tix by Molmil
Crystal structure of penicillin-binding protein 2 from Yersinia pestis in complex with mecillinam
Descriptor: 2-[(1R)-1-{[(E)-azepan-1-ylmethylidene]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Peptidoglycan D,D-transpeptidase MrdA
Authors:Pankov, G, Hunter, W.N, Dawson, A.
Deposit date:2019-11-22
Release date:2020-12-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structure of penicillin-binding protein 2 from Yersinia pestis in complex with mecillinam
To Be Published
2HPS
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BU of 2hps by Molmil
Crystal structure of coelenterazine-binding protein from Renilla Muelleri
Descriptor: C2-HYDROXY-COELENTERAZINE, GLYCEROL, coelenterazine-binding protein with bound coelenterazine
Authors:Stepanyuk, G, Liu, Z.J, Vysotski, E.S, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-07-17
Release date:2007-01-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:Crystal structure of coelenterazine-binding protein from Renilla muelleri at 1.7 A: why it is not a calcium-regulated photoprotein.
PHOTOCHEM.PHOTOBIOL.SCI., 7, 2008
2HPW
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BU of 2hpw by Molmil
Green fluorescent protein from Clytia gregaria
Descriptor: Green fluorescent protein
Authors:Stepanyuk, G, Liu, Z.J, Vysotski, S.E, Lee, J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics (SECSG)
Deposit date:2006-07-17
Release date:2006-09-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Crystal Structure of Green Fluorescent Protein from Clytia Gregaria at 1.55 A resolution
To be Published
4XX8
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BU of 4xx8 by Molmil
Crystal structure of Pro1 deletion mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, Macrophage migration inhibitory factor, SULFATE ION
Authors:Pantouris, G, Lolis, E.
Deposit date:2015-01-30
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015
4XX7
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BU of 4xx7 by Molmil
Crystal structure of M2A mutant of human macrophage migration inhibitory factor
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Macrophage migration inhibitory factor, ...
Authors:Pantouris, G, Lolis, E.
Deposit date:2015-01-29
Release date:2015-09-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:An Analysis of MIF Structural Features that Control Functional Activation of CD74.
Chem.Biol., 22, 2015

 

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