7OLE
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![BU of 7ole by Molmil](/molmil-images/mine/7ole) | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | Authors: | Pal, M, Llorca, O, Pearl, L. | Deposit date: | 2021-05-19 | Release date: | 2021-07-07 | Last modified: | 2021-10-06 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone. Cell Rep, 36, 2021
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6FM8
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![BU of 6fm8 by Molmil](/molmil-images/mine/6fm8) | RPAP3 c-terminus | Descriptor: | RNA polymerase II-associated protein 3 | Authors: | Pal, M, Roe, S.M. | Deposit date: | 2018-01-30 | Release date: | 2019-03-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex Nat Commun, 2020
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3NFT
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![BU of 3nft by Molmil](/molmil-images/mine/3nft) | Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei | Descriptor: | Translocator protein bipD | Authors: | Pal, M, Erskine, P.T, Gill, R.S, Wood, S.P, Cooper, J.B. | Deposit date: | 2010-06-10 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr.,Sect.F, 66, 2010
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6X24
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![BU of 6x24 by Molmil](/molmil-images/mine/6x24) | Structural basis of plant blue light photoreceptor | Descriptor: | Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | Authors: | Palayam, M, Ganapathy, J, Guercio, M.A, Shabek, N. | Deposit date: | 2020-05-19 | Release date: | 2020-12-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.25 Å) | Cite: | Structural insights into photoactivation of plant Cryptochrome-2. Commun Biol, 4, 2021
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5KKV
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![BU of 5kkv by Molmil](/molmil-images/mine/5kkv) | |
3U0X
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![BU of 3u0x by Molmil](/molmil-images/mine/3u0x) | |
3U0Y
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![BU of 3u0y by Molmil](/molmil-images/mine/3u0y) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with compound 382 and UDP | Descriptor: | 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine, GLYCEROL, Histo-blood group ABO system transferase, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-09-29 | Release date: | 2012-10-24 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A novel compound from a molecular fragment library screen inhibits glycosyltransferases by displacing the metal ion and interfering with substrate binding To be Published
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3V0N
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![BU of 3v0n by Molmil](/molmil-images/mine/3v0n) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (3GW and 4GW) | Descriptor: | 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), 5-(5-formylthiophen-2-yl)uridine-5'(2-(acetylamino)-2-deoxy-alpha-D-galactosyl)-diphosphate, GLYCEROL, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase. J.Biol.Chem., 288, 2013
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3V0Q
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![BU of 3v0q by Molmil](/molmil-images/mine/3v0q) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with UDP and H-antigen acceptor | Descriptor: | GLYCEROL, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
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3V0L
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![BU of 3v0l by Molmil](/molmil-images/mine/3v0l) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (2GW) | Descriptor: | 5-phenyl-uridine-5'-alpha-d-galactosyl-diphosphate, Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
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5WVX
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![BU of 5wvx by Molmil](/molmil-images/mine/5wvx) | Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza | Descriptor: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID, Trypsin/chymotrypsin inhibitor | Authors: | Palayam, M, Radhakrishnan, M, Lakshminarayanan, K, Balu, K.E, Ganapathy, J, Krishnasamy, G. | Deposit date: | 2016-12-29 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.003 Å) | Cite: | Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition. Int. J. Biol. Macromol., 113, 2018
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3V0P
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![BU of 3v0p by Molmil](/molmil-images/mine/3v0p) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (4GW) and H-antigen acceptor | Descriptor: | 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
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3V0M
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![BU of 3v0m by Molmil](/molmil-images/mine/3v0m) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (5GW) and H-antigen acceptor | Descriptor: | 5-phenyluridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
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3V0O
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![BU of 3v0o by Molmil](/molmil-images/mine/3v0o) | Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-GalNAc derived inhibitor (4GW) and H-antigen acceptor | Descriptor: | 5-(5-formylthiophen-2-yl)uridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... | Authors: | Palcic, M.M, Jorgensen, R. | Deposit date: | 2011-12-08 | Release date: | 2013-01-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Base-modified donor analogues reveal novel dynamic features of a glycosyltransferase. J.Biol.Chem., 288, 2013
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7SA1
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![BU of 7sa1 by Molmil](/molmil-images/mine/7sa1) | LRR-F-Box plant ubiquitin ligase | Descriptor: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, F-box/LRR-repeat MAX2 homolog, ... | Authors: | Palayam, M, Shabek, N. | Deposit date: | 2021-09-21 | Release date: | 2022-04-20 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.21 Å) | Cite: | A conformational switch in the SCF-D3/MAX2 ubiquitin ligase facilitates strigolactone signalling. Nat.Plants, 8, 2022
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5HHD
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![BU of 5hhd by Molmil](/molmil-images/mine/5hhd) | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21 | Descriptor: | D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ... | Authors: | Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | Deposit date: | 2016-01-10 | Release date: | 2016-03-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
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5HHC
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![BU of 5hhc by Molmil](/molmil-images/mine/5hhc) | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n | Descriptor: | D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A | Authors: | Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | Deposit date: | 2016-01-10 | Release date: | 2016-03-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo. Acs Chem.Biol., 11, 2016
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7UPV
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![BU of 7upv by Molmil](/molmil-images/mine/7upv) | |
7EH3
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4CGQ
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![BU of 4cgq by Molmil](/molmil-images/mine/4cgq) | Full length Tah1 bound to HSP90 peptide SRMEEVD | Descriptor: | CHLORIDE ION, HEAT SHOCK PROTEIN HSP 90-ALPHA, TPR REPEAT-CONTAINING PROTEIN ASSOCIATED WITH HSP90 | Authors: | Roe, S.M, Pal, M. | Deposit date: | 2013-11-26 | Release date: | 2014-12-17 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Tah1 Helix-Swap Dimerization Prevents Mixed Hsp90 Co-Chaperone Complexes Acta Crystallogr.,Sect.F, 71, 2015
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4CHH
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![BU of 4chh by Molmil](/molmil-images/mine/4chh) | N-terminal domain of yeast PIH1p | Descriptor: | 1,2-ETHANEDIOL, PROTEIN INTERACTING WITH HSP90 1 | Authors: | Roe, S.M, Pal, M. | Deposit date: | 2013-12-02 | Release date: | 2014-05-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1. Structure, 22, 2014
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4CGU
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![BU of 4cgu by Molmil](/molmil-images/mine/4cgu) | Full length Tah1 bound to yeast PIH1 and HSP90 peptide SRMEEVD | Descriptor: | GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, PROTEIN INTERACTING WITH HSP90 1, ... | Authors: | Roe, S.M, Pal, M. | Deposit date: | 2013-11-26 | Release date: | 2014-05-14 | Last modified: | 2017-06-28 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1. Structure, 22, 2014
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4CGW
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![BU of 4cgw by Molmil](/molmil-images/mine/4cgw) | |
4CGV
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![BU of 4cgv by Molmil](/molmil-images/mine/4cgv) | First TPR of Spaghetti (RPAP3) bound to HSP90 peptide SRMEEVD | Descriptor: | GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, RNA POLYMERASE II-ASSOCIATED PROTEIN 3 | Authors: | Roe, S.M, Pal, M. | Deposit date: | 2013-11-26 | Release date: | 2014-05-14 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.54 Å) | Cite: | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1. Structure, 22, 2014
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4GLS
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![BU of 4gls by Molmil](/molmil-images/mine/4gls) | Crystal Structure of Chemically Synthesized Heterochiral {D-Protein Antagonist plus VEGF-A} Protein Complex in space group P21 | Descriptor: | D- RFX001, D- Vascular endothelial growth factor-A, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mandal, K, Uppalapati, M, Ault-Riche, D, Kenney, J, Lowitz, J, Sidhu, S, Kent, S.B.H. | Deposit date: | 2012-08-14 | Release date: | 2012-09-05 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Chemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallography. Proc.Natl.Acad.Sci.USA, 109, 2012
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