1EMM
 
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1EML
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1EMC
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2C45
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2H4C
 | | Structure of Daboiatoxin (heterodimeric PLA2 venom) | | Descriptor: | Phospholipase A2-II, Phospholipase A2-III | | Authors: | Gopalan, G, Thwin, M.M, Gopalakrishnakone, P, Swaminathan, K. | | Deposit date: | 2006-05-24 | | Release date: | 2007-05-29 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural and pharmacological comparison of daboiatoxin from Daboia russelli siamensis with viperotoxin F and vipoxin from other vipers.
ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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1U79
 | | Crystal structure of AtFKBP13 | | Descriptor: | FKBP-type peptidyl-prolyl cis-trans isomerase 3 | | Authors: | Gopalan, G, Swaminathan, K. | | Deposit date: | 2004-08-03 | | Release date: | 2004-09-28 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural analysis uncovers a role for redox in regulating FKBP13, an immunophilin of the chloroplast thylakoid lumen
Proc.Natl.Acad.Sci.Usa, 101, 2004
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1EMK
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1EMF
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1EME
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2EMN
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2EMD
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2EMO
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2XQQ
 | | Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide (Ac-SRGTQTE). | | Descriptor: | ACETATE ION, DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, ... | | Authors: | Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. | | Deposit date: | 2010-09-07 | | Release date: | 2011-05-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.31 Å) | | Cite: | Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
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3P8M
 | | Human dynein light chain (DYNLL2) in complex with an in vitro evolved peptide dimerized by leucine zipper | | Descriptor: | Dynein light chain 2, General control protein GCN4 | | Authors: | Rapali, P, Radnai, L, Suveges, D, Hetenyi, C, Harmat, V, Tolgyesi, F, Wahlgren, W.Y, Katona, G, Nyitray, L, Pal, G. | | Deposit date: | 2010-10-14 | | Release date: | 2011-08-31 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
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2XTT
 | | Bovine trypsin in complex with evolutionary enhanced Schistocerca gregaria protease inhibitor 1 (SGPI-1-P02) | | Descriptor: | ACETATE ION, CALCIUM ION, CATIONIC TRYPSIN, ... | | Authors: | Wahlgren, W.Y, Pal, G, Kardos, J, Porrogi, P, Szenthe, B, Patthy, A, Graf, L, Katona, G. | | Deposit date: | 2010-10-12 | | Release date: | 2010-11-10 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (0.93 Å) | | Cite: | The catalytic aspartate is protonated in the Michaelis complex formed between trypsin and an in vitro evolved substrate-like inhibitor: a refined mechanism of serine protease action.
J.Biol.Chem., 286, 2011
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4DJZ
 | | Catalytic fragment of masp-1 in complex with its specific inhibitor developed by directed evolution on sgci scaffold | | Descriptor: | Mannan-binding lectin serine protease 1 heavy chain, Mannan-binding lectin serine protease 1 light chain, Protease inhibitor SGPI-2 | | Authors: | Heja, D, Harmat, V, Fodor, K, Wilmanns, M, Dobo, J, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. | | Deposit date: | 2012-02-03 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
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3TVJ
 | | Catalytic fragment of MASP-2 in complex with its specific inhibitor developed by directed evolution on SGCI scaffold | | Descriptor: | Mannan-binding lectin serine protease 2 A chain, Mannan-binding lectin serine protease 2 B chain, Protease inhibitor SGPI-2, ... | | Authors: | Heja, D, Harmat, V, Dobo, J, Szasz, R, Kekesi, K.A, Zavodszky, P, Gal, P, Pal, G. | | Deposit date: | 2011-09-20 | | Release date: | 2012-04-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.28 Å) | | Cite: | Monospecific Inhibitors Show That Both Mannan-binding Lectin-associated Serine Protease-1 (MASP-1) and -2 Are Essential for Lectin Pathway Activation and Reveal Structural Plasticity of MASP-2.
J.Biol.Chem., 287, 2012
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8CMX
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8A43
 | | Human RNA polymerase I | | Descriptor: | DNA-directed RNA polymerase I subunit RPA1, DNA-directed RNA polymerase I subunit RPA12, DNA-directed RNA polymerase I subunit RPA2, ... | | Authors: | Daiss, J.L, Pilsl, M, Straub, K, Bleckmann, A, Hoecherl, M, Heiss, F.B, Abascal-Palacios, G, Ramsay, E, Tluckova, K, Mars, J.C, Fuertges, T, Bruckmann, A, Rudack, T, Bernecky, C, Lamour, V, Panov, K, Vannini, A, Moss, T, Engel, C. | | Deposit date: | 2022-06-10 | | Release date: | 2022-08-31 | | Last modified: | 2022-11-02 | | Method: | ELECTRON MICROSCOPY (4.09 Å) | | Cite: | The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans.
Life Sci Alliance, 5, 2022
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5VOE
 | | DesGla-XaS195A Bound to Aptamer 11F7t | | Descriptor: | Aptamer 11F7t (36-MER), CALCIUM ION, Coagulation factor X, ... | | Authors: | Gunaratne, R, Kumar, S, Frederiksen, J.W, Stayrook, S, Lohrmann, J.L, Perry, K, Chabata, C.V, Thalji, N.K, Ho, M.D, Arepally, G, Camire, R.M, Krishnaswamy, S.K, Sullenger, B.A. | | Deposit date: | 2017-05-02 | | Release date: | 2018-06-20 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.
Nat. Biotechnol., 36, 2018
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7OB2
 | | NMR structure of the antimicrobial RiLK1 peptide in SDS micelles | | Descriptor: | RiLK1 | | Authors: | Falcigno, L, D'Auria, G, Palmieri, G, Gogliettino, M, Agrillo, B. | | Deposit date: | 2021-04-20 | | Release date: | 2021-11-17 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Key Physicochemical Determinants in the Antimicrobial Peptide RiLK1 Promote Amphipathic Structures.
Int J Mol Sci, 22, 2021
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8AYF
 | | Crystal structure of human Sphingosine-1-phosphate lyase 1 | | Descriptor: | ACETATE ION, GLYCEROL, Sphingosine-1-phosphate lyase 1 | | Authors: | Giardina, G, Catalano, F, Pampalone, G, Cellini, B. | | Deposit date: | 2022-09-02 | | Release date: | 2023-09-13 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Dual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study.
Sci Rep, 13, 2023
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7Q5B
 | | Cryo-EM structure of Ty3 retrotransposon targeting a TFIIIB-bound tRNA gene | | Descriptor: | DNA (19-MER), DNA (31-MER), DNA (34-MER), ... | | Authors: | Abascal-Palacios, G, Jochem, L, Pla-Prats, C, Beuron, F, Vannini, A. | | Deposit date: | 2021-11-03 | | Release date: | 2022-01-26 | | Method: | ELECTRON MICROSCOPY (3.98 Å) | | Cite: | Structural basis of Ty3 retrotransposon integration at RNA Polymerase III-transcribed genes.
Nat Commun, 12, 2021
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5MIY
 | | Crystal structure of the E3 ubiquitin ligase RavN from Legionella pneumophila | | Descriptor: | 1,2-ETHANEDIOL, E3 ubiquitin ligase RavN, SODIUM ION, ... | | Authors: | Lucas, M, Abascal-Palacios, G, Rojas, A.L, Hierro, A. | | Deposit date: | 2016-11-29 | | Release date: | 2018-05-23 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.717 Å) | | Cite: | RavN is a member of a previously unrecognized group of Legionella pneumophila E3 ubiquitin ligases.
PLoS Pathog., 14, 2018
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1GVL
 | | Human prokallikrein 6 (hK6)/ prozyme/ proprotease M/ proneurosin | | Descriptor: | KALLIKREIN 6 | | Authors: | Gomis-Ruth, F.X, Bayes, A, Sotiropoulou, G, Pampalakis, G, Tsetsenis, T, Villegas, V, Aviles, F.X, Coll, M. | | Deposit date: | 2002-02-14 | | Release date: | 2002-05-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Structure of Human Prokallikrein 6 Reveals a Novel Activation Mechanism for the Kallikrein Family.
J.Biol.Chem., 277, 2002
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