5VOE

DesGla-XaS195A Bound to Aptamer 11F7t

Summary for 5VOE

• Entry DOI: 10.2210/pdb5voe/pdb
• Descriptor: Coagulation factor X, Aptamer 11F7t (36-MER), SODIUM ION, ... (7 entities in total)
• Functional Keywords: serine protease, blood coagulation, aptamer, inhibitor, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 43440.45

Authors

Gunaratne, R.,Kumar, S.,Frederiksen, J.W.,Stayrook, S.,Lohrmann, J.L.,Perry, K.,Chabata, C.V.,Thalji, N.K.,Ho, M.D.,Arepally, G.,Camire, R.M.,Krishnaswamy, S.K.,Sullenger, B.A. (deposition date: 2017-05-02, release date: 2018-06-20, Last modification date: 2023-10-04)

• Primary citation: Gunaratne, R.,Kumar, S.,Frederiksen, J.W.,Stayrook, S.,Lohrmann, J.L.,Perry, K.,Bompiani, K.M.,Chabata, C.V.,Thalji, N.K.,Ho, M.D.,Arepally, G.,Camire, R.M.,Krishnaswamy, S.,Sullenger, B.A.; Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass.; Nat. Biotechnol., 36:606-613, 2018; PubMed: 29863725; DOI: 10.1038/nbt.4153

Experimental method

X-RAY DIFFRACTION (2 Å)