4PVE
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![BU of 4pve by Molmil](/molmil-images/mine/4pve) | Wild-type Phl p 4.0202, a glucose dehydrogenase | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, MALONATE ION, ... | Authors: | Zafred, D, Teufelberger, A, Keller, W, Macheroux, P. | Deposit date: | 2014-03-17 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction. Febs J., 282, 2015
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8FTU
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![BU of 8ftu by Molmil](/molmil-images/mine/8ftu) | Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure | Descriptor: | Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1 | Authors: | Travis, S.M, Jeffrey, P.D, Hughson, F.M. | Deposit date: | 2023-01-13 | Release date: | 2023-03-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (5.73 Å) | Cite: | Structure of a membrane tethering complex incorporating multiple SNAREs. Nat.Struct.Mol.Biol., 31, 2024
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6Y6L
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![BU of 6y6l by Molmil](/molmil-images/mine/6y6l) | Structure the ananain protease from Ananas comosus with a thiomethylated catalytic cysteine | Descriptor: | Ananain, GLYCEROL, SULFATE ION | Authors: | Azarkan, M, Charlier, P, Herman, R, Delbrassine, F, Sauvage, E, M Rabet, N, Calvo Esposito, R, Kerff, F. | Deposit date: | 2020-02-26 | Release date: | 2020-11-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of the free and inhibitors-bound forms of bromelain and ananain from Ananas comosus stem and in vitro study of their cytotoxicity. Sci Rep, 10, 2020
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8CGP
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![BU of 8cgp by Molmil](/molmil-images/mine/8cgp) | Insulin regulated aminopeptidase (IRAP) in complex with an allosteric aryl sulfonamide inhibitor | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Mpakali, A, Stratikos, E, Giastas, P. | Deposit date: | 2023-02-06 | Release date: | 2024-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.62 Å) | Cite: | Mechanisms of Allosteric Inhibition of Insulin-Regulated Aminopeptidase. J.Mol.Biol., 436, 2024
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8C7I
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6Y1C
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![BU of 6y1c by Molmil](/molmil-images/mine/6y1c) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant D54F | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | Deposit date: | 2020-02-11 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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8CP4
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![BU of 8cp4 by Molmil](/molmil-images/mine/8cp4) | [4Fe-4S] cluster containing LarE in complex with AMP | Descriptor: | ADENOSINE MONOPHOSPHATE, CHLORIDE ION, IRON/SULFUR CLUSTER, ... | Authors: | Zecchin, P, Pecqueur, L, Golinelli-Pimpaneau, B. | Deposit date: | 2023-03-01 | Release date: | 2024-01-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Structure-based insights into the mechanism of [4Fe-4S]-dependent sulfur insertase LarE. Protein Sci., 33, 2024
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8OXA
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![BU of 8oxa by Molmil](/molmil-images/mine/8oxa) | Cryo-EM structure of ATP8B1-CDC50A in E2-Pi conformation with occluded PS | Descriptor: | (2~{S})-2-azanyl-3-[[(2~{R})-3-hexadecanoyloxy-2-[(~{Z})-octadec-9-enoyl]oxy-propoxy]-oxidanyl-phosphoryl]oxy-propanoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Cell cycle control protein 50A, ... | Authors: | Dieudonne, T, Kummerer, F, Juknaviciute Laursen, M, Stock, C, Kock Flygaard, R, Khalid, S, Lenoir, G, Lyons, J.A, Lindorff-Larsen, K, Nissen, P. | Deposit date: | 2023-05-01 | Release date: | 2023-11-29 | Method: | ELECTRON MICROSCOPY (2.76 Å) | Cite: | Activation and substrate specificity of the human P4-ATPase ATP8B1. Nat Commun, 14, 2023
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7SGD
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![BU of 7sgd by Molmil](/molmil-images/mine/7sgd) | Lassa virus glycoprotein construct(Josiah GPCysR4) recovered from GPC-I53-50 nanoparticle by localized reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Antanasijevic, A, Brouwer, P.J.M, Ward, A.B. | Deposit date: | 2021-10-05 | Release date: | 2022-10-12 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.97 Å) | Cite: | Lassa virus glycoprotein nanoparticles elicit neutralizing antibody responses and protection. Cell Host Microbe, 30, 2022
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2UUB
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![BU of 2uub by Molmil](/molmil-images/mine/2uub) | Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a Valine-ASL with cmo5U in position 34 bound to an mRNA with a GUU-codon in the A-site and paromomycin. | Descriptor: | 16S Ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Weixlbaumer, A, Murphy, F.V, Dziergowska, A, Malkiewicz, A, Vendeix, F.A.P, Agris, P.F, Ramakrishnan, V. | Deposit date: | 2007-03-01 | Release date: | 2007-05-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Mechanism for Expanding the Decoding Capacity of Transfer Rnas by Modification of Uridines Nat.Struct.Mol.Biol., 14, 2007
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8PMS
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![BU of 8pms by Molmil](/molmil-images/mine/8pms) | NADase from Aspergillus fumigatus with replaced C-terminus from Neurospora crassa | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Kallio, J.P, Ferrario, E, Stromland, O, Ziegler, M. | Deposit date: | 2023-06-29 | Release date: | 2023-11-15 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase. Biochemistry, 62, 2023
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8FBJ
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![BU of 8fbj by Molmil](/molmil-images/mine/8fbj) | |
8TXN
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5FM2
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![BU of 5fm2 by Molmil](/molmil-images/mine/5fm2) | Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment | Descriptor: | 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET | Authors: | Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q. | Deposit date: | 2015-10-30 | Release date: | 2016-12-28 | Last modified: | 2019-04-24 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements. Cell Rep, 17, 2016
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6Y5H
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![BU of 6y5h by Molmil](/molmil-images/mine/6y5h) | Ectodomain of X-31 Haemagglutinin at pH 5 (State I) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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1BWB
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![BU of 1bwb by Molmil](/molmil-images/mine/1bwb) | HIV-1 PROTEASE (V82F/I84V) DOUBLE MUTANT COMPLEXED WITH SD146 OF DUPONT PHARMACEUTICALS | Descriptor: | PROTEIN (HIV-1 PROTEASE), [4R-(4ALPHA,5ALPHA,6ALPHA,7ALPHA)]-3,3'-{{TETRAHYDRO-5,6-DIHYDROXY-2-OXO-4,7-BIS(PHENYLMETHYL)-1H-1,3-DIAZEPINE-1,3(2H)-DIYL]BIS(METHYLENE)]BIS[N-1H-BENZIMIDAZOL-2-YLBENZAMIDE] | Authors: | Ala, P, Chang, C.H. | Deposit date: | 1998-09-22 | Release date: | 1998-09-30 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Counteracting HIV-1 protease drug resistance: structural analysis of mutant proteases complexed with XV638 and SD146, cyclic urea amides with broad specificities. Biochemistry, 37, 1998
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8FBI
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![BU of 8fbi by Molmil](/molmil-images/mine/8fbi) | |
7SA8
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![BU of 7sa8 by Molmil](/molmil-images/mine/7sa8) | |
6UPH
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![BU of 6uph by Molmil](/molmil-images/mine/6uph) | Structure of a Yeast Centromeric Nucleosome at 2.7 Angstrom resolution | Descriptor: | DNA (119-MER), Histone H2A, Histone H2B.1, ... | Authors: | Migl, D, Kschonsak, M, Arthur, C.P, Khin, Y, Harrison, S.C, Ciferri, C, Dimitrova, Y.N. | Deposit date: | 2019-10-17 | Release date: | 2019-11-06 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryoelectron Microscopy Structure of a Yeast Centromeric Nucleosome at 2.7 angstrom Resolution. Structure, 28, 2020
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6Y5I
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![BU of 6y5i by Molmil](/molmil-images/mine/6y5i) | Dilated form 1 of X-31 Influenza Haemagglutinin at pH 5 (State II) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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6Y72
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![BU of 6y72 by Molmil](/molmil-images/mine/6y72) | Pseudomonas stutzeri nitrous oxide reductase mutant, H178A | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Zhang, L, Kroneck, P.M.H, Einsle, O. | Deposit date: | 2020-02-27 | Release date: | 2021-01-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | A [3Cu:2S] cluster provides insight into the assembly and function of the Cu Z site of nitrous oxide reductase. Chem Sci, 12, 2021
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8CD4
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![BU of 8cd4 by Molmil](/molmil-images/mine/8cd4) | structure of HEX-1 from N. crassa crystallized in cellulo (cytosol), diffracted at 100K and resolved using CrystFEL | Descriptor: | Woronin body major protein | Authors: | Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L. | Deposit date: | 2023-01-30 | Release date: | 2024-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
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6Y5G
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![BU of 6y5g by Molmil](/molmil-images/mine/6y5g) | Ectodomain of X-31 Haemagglutinin at pH 8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, X-31 Influenza Haemagglutinin HA1, ... | Authors: | Benton, D.J, Rosenthal, P.B. | Deposit date: | 2020-02-25 | Release date: | 2020-06-10 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural transitions in influenza haemagglutinin at membrane fusion pH. Nature, 583, 2020
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7S24
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![BU of 7s24 by Molmil](/molmil-images/mine/7s24) | Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL | Authors: | Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R. | Deposit date: | 2021-09-03 | Release date: | 2022-08-10 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing. Nat Commun, 13, 2022
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8U66
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![BU of 8u66 by Molmil](/molmil-images/mine/8u66) | Firmicutes Rubisco | Descriptor: | 2-CARBOXYARABINITOL-1,5-DIPHOSPHATE, MAGNESIUM ION, Rubisco | Authors: | Kaeser, B.P, Liu, A.K, Shih, P.M. | Deposit date: | 2023-09-13 | Release date: | 2023-11-22 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.21 Å) | Cite: | Deep-branching evolutionary intermediates reveal structural origins of form I rubisco. Curr.Biol., 33, 2023
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