3BWF
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![BU of 3bwf by Molmil](/molmil-images/mine/3bwf) | Crystal structure of the human Pim1 in complex with an osmium compound | Descriptor: | PYRIDOCARBAZOLE CYCLOPENTADIENYL OS(CO) COMPLEX, Proto-oncogene serine/threonine-protein kinase Pim-1, SULFATE ION | Authors: | Maksimoska, J, Filippakopoulos, P, Knapp, S, Meggers, E. | Deposit date: | 2008-01-09 | Release date: | 2008-06-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Similar biological activities of two isostructural ruthenium and osmium complexes. Chemistry, 14, 2008
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2HA2
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![BU of 2ha2 by Molmil](/molmil-images/mine/2ha2) | Crystal structure of mouse acetylcholinesterase complexed with succinylcholine | Descriptor: | 2,2'-[(1,4-DIOXOBUTANE-1,4-DIYL)BIS(OXY)]BIS(N,N,N-TRIMETHYLETHANAMINIUM), 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Bourne, Y, Radic, Z, Sulzenbacher, G, Kim, E, Taylor, P, Marchot, P. | Deposit date: | 2006-06-12 | Release date: | 2006-07-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding J.Biol.Chem., 281, 2006
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2HBN
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1IDF
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![BU of 1idf by Molmil](/molmil-images/mine/1idf) | ISOCITRATE DEHYDROGENASE K230M MUTANT APO ENZYME | Descriptor: | ISOCITRATE DEHYDROGENASE | Authors: | Bolduc, J.M, Dyer, D.H, Scott, W.G, Singer, P, Sweet, R.M, Koshland Junior, D.E, Stoddard, B.L. | Deposit date: | 1995-01-18 | Release date: | 1996-03-08 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Mutagenesis and Laue structures of enzyme intermediates: isocitrate dehydrogenase. Science, 268, 1995
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1SSA
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![BU of 1ssa by Molmil](/molmil-images/mine/1ssa) | A STRUCTURAL INVESTIGATION OF CATALYTICALLY MODIFIED F12OL AND F12OY SEMISYNTHETIC RIBONUCLEASES | Descriptor: | RIBONUCLEASE A, SULFATE ION | Authors: | deMel, V.S.J, Doscher, M.S, Glinn, M.A, Martin, P.D, Ram, M.L, Edwards, B.F.P. | Deposit date: | 1993-08-03 | Release date: | 1994-09-30 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural investigation of catalytically modified F120L and F120Y semisynthetic ribonucleases. Protein Sci., 3, 1994
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3C84
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![BU of 3c84 by Molmil](/molmil-images/mine/3c84) | Crystal structure of a complex of AChBP from aplysia californica and the neonicotinoid thiacloprid | Descriptor: | ISOPROPYL ALCOHOL, MAGNESIUM ION, Soluble acetylcholine receptor, ... | Authors: | Talley, T.T, Harel, M, Hibbs, R.E, Tomizawa, M, Casida, J.E, Taylor, P.W. | Deposit date: | 2008-02-08 | Release date: | 2008-05-20 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore. Proc.Natl.Acad.Sci.Usa, 105, 2008
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1T8C
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![BU of 1t8c by Molmil](/molmil-images/mine/1t8c) | Structure of the C-type lectin domain of CD23 | Descriptor: | Low affinity immunoglobulin epsilon Fc receptor | Authors: | Hibbert, R.G, Teriete, P, Grundy, G.J, Sutton, B.J, Gould, H.J, McDonnell, J.M. | Deposit date: | 2004-05-12 | Release date: | 2005-07-26 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | The structure of human CD23 and its interactions with IgE and CD21 J.Exp.Med., 202, 2005
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1SUL
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![BU of 1sul by Molmil](/molmil-images/mine/1sul) | Crystal Structure of the apo-YsxC | Descriptor: | GTP-binding protein YsxC | Authors: | Ruzheinikov, S.N, Das, K.S, Sedelnikova, S.E, Baker, P.J, Artymiuk, P.J, Garcia-Lara, J, Foster, S.J, Rice, D.W. | Deposit date: | 2004-03-26 | Release date: | 2004-05-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analysis of the Open and Closed Conformations of the GTP-binding Protein YsxC from Bacillus subtilis. J.Mol.Biol., 339, 2004
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4NB0
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![BU of 4nb0 by Molmil](/molmil-images/mine/4nb0) | Crystal Structure of FosB from Staphylococcus aureus with BS-Cys9 disulfide at 1.62 Angstrom Resolution | Descriptor: | CYSTEINE, GLYCEROL, Metallothiol transferase FosB, ... | Authors: | Thompson, M.K, Goodman, M.C, Jagessar, K, Harp, J, Keithly, M.E, Cook, P.D, Armstrong, R.N. | Deposit date: | 2013-10-22 | Release date: | 2014-02-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Structure and Function of the Genomically Encoded Fosfomycin Resistance Enzyme, FosB, from Staphylococcus aureus. Biochemistry, 53, 2014
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1NIP
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![BU of 1nip by Molmil](/molmil-images/mine/1nip) | CRYSTALLOGRAPHIC STRUCTURE OF THE NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, IRON/SULFUR CLUSTER, MAGNESIUM ION, ... | Authors: | Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C. | Deposit date: | 1992-09-29 | Release date: | 1993-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystallographic structure of the nitrogenase iron protein from Azotobacter vinelandii. Science, 257, 1992
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1TC1
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![BU of 1tc1 by Molmil](/molmil-images/mine/1tc1) | A 1.4 ANGSTROM CRYSTAL STRUCTURE FOR THE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE OF TRYPANOSOMA CRUZI | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FORMYCIN B, PROTEIN (HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE) | Authors: | Focia, P.J, Craig III, S.P, Nieves-Alicea, R, Fletterick, R.J, Eakin, A.E. | Deposit date: | 1998-09-30 | Release date: | 1999-10-07 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.41 Å) | Cite: | A 1.4 A crystal structure for the hypoxanthine phosphoribosyltransferase of Trypanosoma cruzi. Biochemistry, 37, 1998
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4JSY
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![BU of 4jsy by Molmil](/molmil-images/mine/4jsy) | Structure of Clostridium thermocellum polynucleotide kinase bound to GTP | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Metallophosphoesterase | Authors: | Das, U, Wang, L.K, Smith, P, Shuman, S. | Deposit date: | 2013-03-22 | Release date: | 2013-08-28 | Last modified: | 2013-12-18 | Method: | X-RAY DIFFRACTION (2.14 Å) | Cite: | Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system. Biochemistry, 52, 2013
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1LB3
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![BU of 1lb3 by Molmil](/molmil-images/mine/1lb3) | Structure of recombinant mouse L chain ferritin at 1.2 A resolution | Descriptor: | CADMIUM ION, FERRITIN LIGHT CHAIN 1, GLYCEROL, ... | Authors: | Granier, T, Langlois D'Estaintot, B, Gallois, B, Chevalier, J.-M, Precigoux, G, Santambrogio, P, Arosio, P. | Deposit date: | 2002-04-02 | Release date: | 2003-01-28 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.21 Å) | Cite: | Structural description of the active sites of mouse L-chain ferritin at 1.2A resolution J.Biol.Inorg.Chem., 8, 2003
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4MLX
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4N2B
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![BU of 4n2b by Molmil](/molmil-images/mine/4n2b) | Crystal structure of Protein Arginine Deiminase 2 (10 mM Ca2+) | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, Protein-arginine deiminase type-2 | Authors: | Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R. | Deposit date: | 2013-10-04 | Release date: | 2015-02-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.69 Å) | Cite: | Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chem.Biol., 10, 2015
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4CXL
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![BU of 4cxl by Molmil](/molmil-images/mine/4cxl) | Human insulin analogue (D-ProB8)-insulin | Descriptor: | CHLORIDE ION, INSULIN A CHAIN, INSULIN B CHAIN | Authors: | Kosinova, L, Veverka, V, Novotna, P, Collinsova, M, Urbanova, M, Jiracek, J, Moody, N.R, Turkenburg, J.P, Brzozowski, A.M, Zakova, L. | Deposit date: | 2014-04-07 | Release date: | 2014-05-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry, 53, 2014
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1T65
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![BU of 1t65 by Molmil](/molmil-images/mine/1t65) | Crystal structure of the androgen receptor ligand binding domain with DHT and a peptide derived form its physiological coactivator GRIP1 NR box 2 bound in a non-helical conformation | Descriptor: | 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Nuclear receptor coactivator 2 | Authors: | Estebanez-Perpina, E, Moore, J.M.R, Mar, E, Nguyen, P, Delgado-Rodrigues, E, Baxter, J.D, Webb, P, Fletterick, R.J, Guy, R.K. | Deposit date: | 2004-05-05 | Release date: | 2005-01-25 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | The Molecular Mechanisms of Coactivator Utilization in Ligand-dependent Transactivation by the Androgen Receptor. J.Biol.Chem., 280, 2005
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1QAM
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![BU of 1qam by Molmil](/molmil-images/mine/1qam) | THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM | Descriptor: | ACETATE ION, ERMC' METHYLTRANSFERASE | Authors: | Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C. | Deposit date: | 1999-03-25 | Release date: | 2000-03-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. J.Mol.Biol., 289, 1999
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1QAQ
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![BU of 1qaq by Molmil](/molmil-images/mine/1qaq) | THE STRUCTURE OF THE RRNA METHYLTRANSFERASE ERMC': IMPLICATIONS FOR THE REACTION MECHANISM | Descriptor: | ERMC' RRNA METHYLTRANSFERASE, SINEFUNGIN | Authors: | Schluckebier, G, Zhong, P, Stewart, K.D, Kavanaugh, T.J, Abad-Zapatero, C. | Deposit date: | 1999-03-28 | Release date: | 2000-03-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The 2.2 A structure of the rRNA methyltransferase ErmC' and its complexes with cofactor and cofactor analogs: implications for the reaction mechanism. J.Mol.Biol., 289, 1999
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1QLP
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![BU of 1qlp by Molmil](/molmil-images/mine/1qlp) | 2.0 ANGSTROM STRUCTURE OF INTACT ALPHA-1-ANTITRYPSIN: A CANONICAL TEMPLATE FOR ACTIVE SERPINS | Descriptor: | ALPHA-1-ANTITRYPSIN | Authors: | Elliott, P.R, Pei, X.Y, Dafforn, T, Read, R.J, Carrell, R.W, Lomas, D.A. | Deposit date: | 1999-09-10 | Release date: | 1999-09-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Topography of a 2.0 A structure of alpha1-antitrypsin reveals targets for rational drug design to prevent conformational disease. Protein Sci., 9, 2000
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1TA3
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![BU of 1ta3 by Molmil](/molmil-images/mine/1ta3) | Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP) | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Endo-1,4-beta-xylanase, ... | Authors: | Payan, F, Leone, P, Furniss, C, Tahir, T, Durand, A, Porciero, S, Manzanares, P, Williamson, G, Gilbert, H.J, Juge, N, Roussel, A. | Deposit date: | 2004-05-19 | Release date: | 2004-07-20 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The Dual Nature of the Wheat Xylanase Protein Inhibitor XIP-I: STRUCTURAL BASIS FOR THE INHIBITION OF FAMILY 10 AND FAMILY 11 XYLANASES. J.Biol.Chem., 279, 2004
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4JFQ
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![BU of 4jfq by Molmil](/molmil-images/mine/4jfq) | A2 HLA complex with L8A heteroclitic variant of Melanoma peptide | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-2-microglobulin, GLYCEROL, ... | Authors: | Rizkallah, P.J, Cole, D.K, Madura, F, Sewell, A.K, Baker, B.M. | Deposit date: | 2013-02-28 | Release date: | 2013-05-29 | Last modified: | 2013-07-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | T-cell receptor specificity maintained by altered thermodynamics. J.Biol.Chem., 288, 2013
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2FI4
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![BU of 2fi4 by Molmil](/molmil-images/mine/2fi4) | Crystal structure of a BPTI variant (Cys14->Ser) in complex with trypsin | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | Authors: | Zakharova, E, Horvath, M.P, Goldenberg, D.P. | Deposit date: | 2005-12-27 | Release date: | 2006-01-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Functional and structural roles of the Cys14-Cys38 disulfide of bovine pancreatic trypsin inhibitor. J.Mol.Biol., 382, 2008
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1LIT
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![BU of 1lit by Molmil](/molmil-images/mine/1lit) | HUMAN LITHOSTATHINE | Descriptor: | LITHOSTATHINE | Authors: | Bertrand, J.A, Pignol, D, Bernard, J.-P, Verdier, J.-M, Dagorn, J.-C, Fontacilla-Camps, J.C. | Deposit date: | 1996-01-17 | Release date: | 1997-01-11 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structure of human lithostathine, the pancreatic inhibitor of stone formation. EMBO J., 15, 1996
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1V92
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![BU of 1v92 by Molmil](/molmil-images/mine/1v92) | Solution structure of the UBA domain from p47, a major cofactor of the AAA ATPase p97 | Descriptor: | NSFL1 cofactor p47 | Authors: | Yuan, X, Simpson, P, Mckeown, C, Kondo, H, Uchiyama, K, Wallis, R, Dreveny, I, Keetch, C, Zhang, X, Robinson, C, Freemont, P, Matthews, S. | Deposit date: | 2004-01-19 | Release date: | 2004-04-06 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Structure, dynamics and interactions of p47, a major adaptor of the AAA ATPase, p97 Embo J., 23, 2004
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