4WX2
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![BU of 4wx2 by Molmil](/molmil-images/mine/4wx2) | Crystal structure of Tryptophan Synthase from Salmonella typhimurium in complex with two F6F molecules in the alpha-site and one F6F molecule in the beta-site | Descriptor: | 1,2-ETHANEDIOL, 2-{[4-(TRIFLUOROMETHOXY)BENZOYL]AMINO}ETHYL DIHYDROGEN PHOSPHATE, DI(HYDROXYETHYL)ETHER, ... | Authors: | Hilario, E, Caulkins, B.G, Young, R.P, Niks, D, Dunn, M.F, Mueller, L.J, Fan, L. | Deposit date: | 2014-11-13 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Visualizing the tunnel in tryptophan synthase with crystallography: Insights into a selective filter for accommodating indole and rejecting water. Biochim.Biophys.Acta, 1864, 2016
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1JQ5
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![BU of 1jq5 by Molmil](/molmil-images/mine/1jq5) | Bacillus Stearothermophilus Glycerol dehydrogenase complex with NAD+ | Descriptor: | Glycerol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION | Authors: | Ruzheinikov, S.N, Burke, J, Sedelnikova, S, Baker, P.J, Taylor, R, Bullough, P.A, Muir, N.M, Gore, M.G, Rice, D.W. | Deposit date: | 2001-08-03 | Release date: | 2001-10-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Glycerol dehydrogenase. structure, specificity, and mechanism of a family III polyol dehydrogenase. Structure, 9, 2001
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1B3C
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![BU of 1b3c by Molmil](/molmil-images/mine/1b3c) | SOLUTION STRUCTURE OF A BETA-NEUROTOXIN FROM THE NEW WORLD SCORPION CENTRUROIDES SCULPTURATUS EWING | Descriptor: | PROTEIN (NEUROTOXIN CSE-I) | Authors: | Jablonsky, M.J, Jackson, P.L, Trent, J.O, Watt, D.D, Krishna, N.R. | Deposit date: | 1998-12-08 | Release date: | 1998-12-16 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of a beta-neurotoxin from the New World scorpion Centruroides sculpturatus Ewing. Biochem.Biophys.Res.Commun., 254, 1999
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1BG5
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![BU of 1bg5 by Molmil](/molmil-images/mine/1bg5) | CRYSTAL STRUCTURE OF THE ANKYRIN BINDING DOMAIN OF ALPHA-NA,K-ATPASE AS A FUSION PROTEIN WITH GLUTATHIONE S-TRANSFERASE | Descriptor: | FUSION PROTEIN OF ALPHA-NA,K-ATPASE WITH GLUTATHIONE S-TRANSFERASE | Authors: | Zhang, Z, Devarajan, P, Morrow, J.S. | Deposit date: | 1998-06-05 | Release date: | 1999-01-13 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the ankyrin-binding domain of alpha-Na,K-ATPase. J.Biol.Chem., 273, 1998
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3S3W
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![BU of 3s3w by Molmil](/molmil-images/mine/3s3w) | Structure of chicken acid-sensing ion channel 1 at 2.6 a resolution and ph 7.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Amiloride-sensitive cation channel 2, ... | Authors: | Dawson, R.J.P, Benz, J, Stohler, P, Tetaz, T, Joseph, C, Huber, S, Schmid, G, Huegin, D, Pflimlin, P, Trube, G, Rudolph, M.G, Hennig, M, Ruf, A. | Deposit date: | 2011-05-18 | Release date: | 2012-05-23 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Acid-sensing ion channel 1 in complex with the gating modifier Psalmotoxin 1. Nat Commun, 3, 2012
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1MWQ
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![BU of 1mwq by Molmil](/molmil-images/mine/1mwq) | Structure of HI0828, a Hypothetical Protein from Haemophilus influenzae with a Putative Active-Site Phosphohistidine | Descriptor: | CACODYLATE ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Willis, M.A, Krajewski, W, Chalamasetty, V.R, Reddy, P, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) | Deposit date: | 2002-09-30 | Release date: | 2003-11-25 | Last modified: | 2019-07-24 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Structure of YciI from Haemophilus influenzae (HI0828) reveals a ferredoxin-like alpha/beta-fold with a histidine/aspartate centered catalytic site Proteins, 59, 2005
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2RER
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8IFF
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![BU of 8iff by Molmil](/molmil-images/mine/8iff) | Cryo-EM structure of Arabidopsis phytochrome A. | Descriptor: | 3-[5-[[(3~{R},4~{R})-3-ethyl-4-methyl-5-oxidanylidene-3,4-dihydropyrrol-2-yl]methyl]-2-[[5-[(4-ethyl-3-methyl-5-oxidanylidene-pyrrol-2-yl)methyl]-3-(3-hydroxy-3-oxopropyl)-4-methyl-1~{H}-pyrrol-2-yl]methyl]-4-methyl-1~{H}-pyrrol-3-yl]propanoic acid, Phytochrome A | Authors: | Ma, L, Zhou, C, Wang, J, Guan, Z, Yin, P. | Deposit date: | 2023-02-17 | Release date: | 2023-08-02 | Last modified: | 2023-10-11 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Plant phytochrome A in the Pr state assembles as an asymmetric dimer. Cell Res., 33, 2023
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1BIK
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![BU of 1bik by Molmil](/molmil-images/mine/1bik) | X-RAY STRUCTURE OF BIKUNIN FROM THE HUMAN INTER-ALPHA-INHIBITOR COMPLEX | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BIKUNIN, SULFATE ION | Authors: | Xu, Y, Carr, P.D, Guss, J.M, Ollis, D.L. | Deposit date: | 1997-11-26 | Release date: | 1999-03-16 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains. J.Mol.Biol., 276, 1998
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3VNM
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![BU of 3vnm by Molmil](/molmil-images/mine/3vnm) | Crystal structures of D-Psicose 3-epimerase with D-sorbose from Clostridium cellulolyticum H10 | Descriptor: | D-sorbose, MANGANESE (II) ION, Xylose isomerase domain protein TIM barrel | Authors: | Chan, H.C, Zhu, Y, Hu, Y, Ko, T.P, Huang, C.H, Ren, F, Chen, C.C, Guo, R.T, Sun, Y. | Deposit date: | 2012-01-17 | Release date: | 2012-08-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein Cell, 3, 2012
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1K0M
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![BU of 1k0m by Molmil](/molmil-images/mine/1k0m) | Crystal structure of a soluble monomeric form of CLIC1 at 1.4 angstroms | Descriptor: | CHLORIDE INTRACELLULAR CHANNEL PROTEIN 1 | Authors: | Harrop, S.J, DeMaere, M.Z, Fairlie, W.D, Reztsova, T, Valenzuela, S.M, Mazzanti, M, Tonini, R, Qiu, M.R, Jankova, L, Warton, K, Bauskin, A.R, Wu, W.M, Pankhurst, S, Campbell, T.J, Breit, S.N, Curmi, P.M.G. | Deposit date: | 2001-09-19 | Release date: | 2001-12-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution. J.Biol.Chem., 276, 2001
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3F5C
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![BU of 3f5c by Molmil](/molmil-images/mine/3f5c) | Structure of Dax-1:LRH-1 complex | Descriptor: | Nuclear receptor subfamily 0 group B member 1, Nuclear receptor subfamily 5 group A member 2 | Authors: | Fletterick, R.J, Sablin, E.P. | Deposit date: | 2008-11-03 | Release date: | 2008-12-23 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structure of corepressor Dax-1 bound to its target nuclear receptor LRH-1. Proc.Natl.Acad.Sci.USA, 105, 2008
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6YPH
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![BU of 6yph by Molmil](/molmil-images/mine/6yph) | Crystal Structure of CK2alpha with Compound 2 bound | Descriptor: | 4-[(4-naphthalen-2-yl-1,3-thiazol-2-yl)amino]-2-oxidanyl-benzoic acid, Casein kinase II subunit alpha | Authors: | Brear, P, Hyvonen, M. | Deposit date: | 2020-04-16 | Release date: | 2020-07-15 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Proposed Allosteric Inhibitors Bind to the ATP Site of CK2 alpha. J.Med.Chem., 63, 2020
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8HVI
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![BU of 8hvi by Molmil](/molmil-images/mine/8hvi) | Activation mechanism of GPR132 by compound NOX-6-7 | Descriptor: | 3-methyl-5-[(4-oxidanylidene-4-phenyl-butanoyl)amino]-1-benzofuran-2-carboxylic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Wang, J.L, Ding, J.H, Sun, J.P, Yu, X. | Deposit date: | 2022-12-26 | Release date: | 2023-10-11 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Functional screening and rational design of compounds targeting GPR132 to treat diabetes. Nat Metab, 5, 2023
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7PCV
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![BU of 7pcv by Molmil](/molmil-images/mine/7pcv) | |
1B9U
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![BU of 1b9u by Molmil](/molmil-images/mine/1b9u) | |
7SZZ
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![BU of 7szz by Molmil](/molmil-images/mine/7szz) | Structure of the smaller diameter PSMalpha3 nanotubes | Descriptor: | Phenol-soluble modulin PSM-alpha-3 | Authors: | Beltran, L.C, Kreutzberger, M.A, Wang, S, Egelman, E.H, Conticello, V.P. | Deposit date: | 2021-11-29 | Release date: | 2022-05-18 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids. Proc.Natl.Acad.Sci.USA, 119, 2022
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1EZT
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![BU of 1ezt by Molmil](/molmil-images/mine/1ezt) | HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR | Descriptor: | REGULATOR OF G-PROTEIN SIGNALING 4 | Authors: | Moy, F.J, Chanda, P.K, Cockett, M.I, Edris, W, Jones, P.G, Mason, K, Semus, S, Powers, R. | Deposit date: | 2000-05-11 | Release date: | 2001-01-15 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR structure of free RGS4 reveals an induced conformational change upon binding Galpha. Biochemistry, 39, 2000
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5YNJ
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![BU of 5ynj by Molmil](/molmil-images/mine/5ynj) | Crystal structure of MERS-CoV nsp16/nsp10 complex bound to m7GpppG | Descriptor: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, ZINC ION, nsp10 protein, ... | Authors: | Wei, S.M, Yang, L, Ke, Z.H, Chen, Y, Guo, D.Y, Fan, C.P. | Deposit date: | 2017-10-24 | Release date: | 2018-12-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.043 Å) | Cite: | Structural insights into the molecular mechanism of MERS Coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex To Be Published
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3VNL
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![BU of 3vnl by Molmil](/molmil-images/mine/3vnl) | Crystal structures of D-Psicose 3-epimerase with D-tagatose from Clostridium cellulolyticum H10 | Descriptor: | D-tagatose, MANGANESE (II) ION, Xylose isomerase domain protein TIM barrel | Authors: | Chan, H.C, Zhu, Y, Hu, Y, Ko, T.P, Huang, C.H, Ren, F, Chen, C.C, Guo, R.T, Sun, Y. | Deposit date: | 2012-01-16 | Release date: | 2012-08-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein Cell, 3, 2012
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3VNK
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![BU of 3vnk by Molmil](/molmil-images/mine/3vnk) | Crystal structures of D-Psicose 3-epimerase with D-fructose from Clostridium cellulolyticum H10 | Descriptor: | D-fructose, MANGANESE (II) ION, Xylose isomerase domain protein TIM barrel | Authors: | Chan, H.C, Zhu, Y, Hu, Y, Ko, T.P, Huang, C.H, Ren, F, Chen, C.C, Guo, R.T, Sun, Y. | Deposit date: | 2012-01-16 | Release date: | 2012-08-01 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Crystal structures of D-psicose 3-epimerase from Clostridium cellulolyticum H10 and its complex with ketohexose sugars. Protein Cell, 3, 2012
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3O4Q
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![BU of 3o4q by Molmil](/molmil-images/mine/3o4q) | |
6Y10
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![BU of 6y10 by Molmil](/molmil-images/mine/6y10) | X-ray structure of Lactobacillus brevis alcohol dehydrogenase mutant Q126H | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, R-specific alcohol dehydrogenase | Authors: | Hermann, J, Bischoff, D, Janowski, R, Niessing, D, Grob, P, Hekmat, D, Weuster-Botz, D. | Deposit date: | 2020-02-10 | Release date: | 2020-02-19 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Controlling Protein Crystallization by Free Energy Guided Design of Interactions at Crystal Contacts Crystals, 11, 2021
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7T0X
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![BU of 7t0x by Molmil](/molmil-images/mine/7t0x) | Structure of the larger diameter PSMalpha3 nanotube | Descriptor: | Phenol-soluble modulin PSM-alpha-3 | Authors: | Kreutzberger, M.A, Wang, S, Beltran, L.C, Egelman, E.H, Conticello, V.P. | Deposit date: | 2021-11-30 | Release date: | 2022-05-18 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Phenol-soluble modulins PSM alpha 3 and PSM beta 2 form nanotubes that are cross-alpha amyloids. Proc.Natl.Acad.Sci.USA, 119, 2022
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5KKK
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![BU of 5kkk by Molmil](/molmil-images/mine/5kkk) | |