6DWG
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7F6T
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7FHA
| Crystal structure of the ATP sulfurylase domain of human PAPSS2 in complex with APS | Descriptor: | ADENOSINE-5'-PHOSPHOSULFATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, POTASSIUM ION, ... | Authors: | Zhang, P, Zhang, L, Zhang, L. | Deposit date: | 2021-07-29 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2. Biochem.Biophys.Res.Commun., 586, 2022
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5EQ6
| Pseudomonas aeruginosa PilM bound to AMP-PNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Type 4 fimbrial biogenesis protein PilM | Authors: | McCallum, M, Tammam, S, Robinson, H, Shah, M, Calmettes, C, Moraes, T, Burrows, L.L, Howell, P.L. | Deposit date: | 2015-11-12 | Release date: | 2016-04-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM. J.Biol.Chem., 291, 2016
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3QVH
| Crystal structure of fosfomycin resistance kinase FomA from Streptomyces wedmorensis complexed with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, FomA protein | Authors: | Pakhomova, S, Bartlett, S.G, Doerner, P.A, Newcomer, M.E. | Deposit date: | 2011-02-25 | Release date: | 2011-07-20 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and biochemical insights into the mechanism of fosfomycin phosphorylation by fosfomycin resistance kinase FomA. Biochemistry, 50, 2011
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1PQ1
| Crystal structure of Bcl-xl/Bim | Descriptor: | Apoptosis regulator Bcl-X, BCL2-like protein 11 | Authors: | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | Deposit date: | 2003-06-17 | Release date: | 2003-09-23 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
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6WJF
| PKA RIIbeta holoenzyme with DnaJB1-PKAc fusion in fibrolamellar hepatoceullar carcinoma | Descriptor: | DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha fusion, cAMP-dependent protein kinase type II-beta regulatory subunit | Authors: | Lu, T.-W, Aoto, P.C, Weng, J.-H, Nielsen, C, Cash, J.N, Hall, J, Zhang, P, Simon, S.M, Cianfrocco, M.A, Taylor, S.S. | Deposit date: | 2020-04-13 | Release date: | 2020-12-02 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (7.5 Å) | Cite: | Structural analyses of the PKA RII beta holoenzyme containing the oncogenic DnaJB1-PKAc fusion protein reveal protomer asymmetry and fusion-induced allosteric perturbations in fibrolamellar hepatocellular carcinoma. Plos Biol., 18, 2020
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7FH3
| Crystal structure of the ATP sulfurylase domain of human PAPSS2 | Descriptor: | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2, SULFATE ION, beta-D-glucopyranose | Authors: | Zhang, P, Zhang, L, Zhang, L. | Deposit date: | 2021-07-29 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural basis for the substrate recognition mechanism of ATP-sulfurylase domain of human PAPS synthase 2. Biochem.Biophys.Res.Commun., 586, 2022
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1PJA
| The crystal structure of palmitoyl protein thioesterase-2 reveals the basis for divergent substrate specificities of the two lysosomal thioesterases (PPT1 and PPT2) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Palmitoyl-protein thioesterase 2 precursor | Authors: | Calero, G, Gupta, P, Nonato, M.C, Tandel, S, Biehl, E.R, Hofmann, S.L, Clardy, J. | Deposit date: | 2003-06-02 | Release date: | 2003-09-02 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2. J.Biol.Chem., 278, 2003
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5IEE
| Murine endoplasmic reticulum alpha-glucosidase II with 1-deoxynojirimycin | Descriptor: | 1,2-ETHANEDIOL, 1-DEOXYNOJIRIMYCIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Caputo, A.T, Roversi, P, Alonzi, D.S, Kiappes, J.L, Zitzmann, N. | Deposit date: | 2016-02-25 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Structures of mammalian ER alpha-glucosidase II capture the binding modes of broad-spectrum iminosugar antivirals. Proc.Natl.Acad.Sci.USA, 113, 2016
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3VJZ
| Crystal structure of the DNA mimic protein DMP19 | Descriptor: | Putative uncharacterized protein | Authors: | Wang, H.-C, Ko, T.-P, Wang, A.H.-J. | Deposit date: | 2011-11-01 | Release date: | 2012-03-14 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Neisseria conserved protein DMP19 is a DNA mimic protein that prevents DNA binding to a hypothetical nitrogen-response transcription factor Nucleic Acids Res., 2012
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3QXH
| Crystal structure of dethiobiotin synthetase (BioD) from Helicobacter pylori complexed with ADP and 8-aminocaprylic acid | Descriptor: | 1,2-ETHANEDIOL, 8-aminooctanoic acid, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Porebski, P.J, Klimecka, M.M, Chruszcz, M, Murzyn, K, Minor, C, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-03-01 | Release date: | 2011-03-30 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | Structural characterization of Helicobacter pylori dethiobiotin synthetase reveals differences between family members. Febs J., 279, 2012
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8CD4
| structure of HEX-1 from N. crassa crystallized in cellulo (cytosol), diffracted at 100K and resolved using CrystFEL | Descriptor: | Woronin body major protein | Authors: | Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L. | Deposit date: | 2023-01-30 | Release date: | 2024-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
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5KT9
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3QZM
| Staphylococcus aureus IsdA NEAT domain H83A variant in complex with heme | Descriptor: | GLYCEROL, Iron-regulated surface determinant protein A, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Grigg, J.C, Mao, C.X, Murphy, M.E.P. | Deposit date: | 2011-03-06 | Release date: | 2011-08-31 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | Iron-Coordinating Tyrosine Is a Key Determinant of NEAT Domain Heme Transfer. J.Mol.Biol., 413, 2011
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8CD6
| structure of HEX-1 (cyto V2) from N. crassa grown in living insect cells, diffracted at 100K and resolved using CrystFEL | Descriptor: | Woronin body major protein | Authors: | Boger, J, Schoenherr, R, Lahey-Rudolph, J.M, Harms, M, Kaiser, J, Nachtschatt, S, Wobbe, M, Koenig, P, Bourenkov, G, Schneider, T, Redecke, L. | Deposit date: | 2023-01-30 | Release date: | 2024-02-21 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | A streamlined approach to structure elucidation using in cellulo crystallized recombinant proteins, InCellCryst. Nat Commun, 15, 2024
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6NDD
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3QSD
| Structure of cathepsin B1 from Schistosoma mansoni in complex with CA074 inhibitor | Descriptor: | ACETATE ION, Cathepsin B-like peptidase (C01 family), DI(HYDROXYETHYL)ETHER, ... | Authors: | Rezacova, P, Jilkova, A, Brynda, J, Horn, M, Mares, M. | Deposit date: | 2011-02-21 | Release date: | 2011-08-10 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structural Basis for Inhibition of Cathepsin B Drug Target from the Human Blood Fluke, Schistosoma mansoni. J.Biol.Chem., 286, 2011
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6D9H
| Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist | Descriptor: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Draper-Joyce, C.J, Khoshouei, M, Thal, D.M, Liang, Y.-L, Nguyen, A.T.N, Furness, S.G.B, Venugopal, H, Baltos, J, Plitzko, J.M, Danev, R, Baumeister, W, May, L.T, Wootten, D, Sexton, P, Glukhova, A, Christopoulos, A. | Deposit date: | 2018-04-29 | Release date: | 2018-06-20 | Last modified: | 2018-07-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the adenosine-bound human adenosine A1receptor-Gicomplex. Nature, 558, 2018
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2ZS9
| Pantothenate kinase from Mycobacterium tuberculosis (MtPanK) in complex with ADP and Pantothenate | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, PANTOTHENOIC ACID, ... | Authors: | Chetnani, B, Das, S, Kumar, P, Surolia, A, Vijayan, M. | Deposit date: | 2008-09-04 | Release date: | 2009-07-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action Acta Crystallogr.,Sect.D, 65, 2009
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3VLN
| Human Glutathione Transferase O1-1 C32S Mutant in Complex with Ascorbic Acid | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ASCORBIC ACID, ... | Authors: | Brock, J, Board, P.G, Oakley, A.J. | Deposit date: | 2011-12-02 | Release date: | 2012-05-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insights into the dehydroascorbate reductase activity of human omega-class glutathione transferases. J.Mol.Biol., 420, 2012
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1PJB
| L-ALANINE DEHYDROGENASE | Descriptor: | L-ALANINE DEHYDROGENASE | Authors: | Baker, P.J, Sawa, Y, Shibata, H, Sedelnikova, S.E, Rice, D.W. | Deposit date: | 1998-06-05 | Release date: | 1999-06-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Analysis of the structure and substrate binding of Phormidium lapideum alanine dehydrogenase. Nat.Struct.Biol., 5, 1998
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2NLW
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3QRL
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7FJL
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