1PJA

The crystal structure of palmitoyl protein thioesterase-2 reveals the basis for divergent substrate specificities of the two lysosomal thioesterases (PPT1 and PPT2)

Summary for 1PJA

Entry DOI	10.2210/pdb1pja/pdb
Related	1EI9
Descriptor	Palmitoyl-protein thioesterase 2 precursor, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... (4 entities in total)
Functional Keywords	hydrolase, glycoprotein, lysosome
Biological source	Homo sapiens (human)
Cellular location	Lysosome: Q9UMR5
Total number of polymer chains	1
Total formula weight	34839.78
Authors	Calero, G.,Gupta, P.,Nonato, M.C.,Tandel, S.,Biehl, E.R.,Hofmann, S.L.,Clardy, J. (deposition date: 2003-06-02, release date: 2003-09-02, Last modification date: 2020-07-29)
Primary citation	Calero, G.,Gupta, P.,Nonato, M.C.,Tandel, S.,Biehl, E.R.,Hofmann, S.L.,Clardy, J. The crystal structure of palmitoyl protein thioesterase-2 (PPT2) reveals the basis for divergent substrate specificities of the two lysosomal thioesterases, PPT1 and PPT2. J.Biol.Chem., 278:37957-37964, 2003 Cited by PubMed: 12855696 DOI: 10.1074/jbc.M301225200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation