5WJ8
 
 | | Crystal Structure of Human Cadherin-23 EC13-14 | | Descriptor: | CALCIUM ION, CHLORIDE ION, Cadherin-23, ... | | Authors: | Velez-Cortes, F, Conghui, C, De-la-Torre, P, Sotomayor, M. | | Deposit date: | 2017-07-21 | | Release date: | 2018-07-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.86 Å) | | Cite: | Zooming in on Cadherin-23: Structural Diversity and Potential Mechanisms of Inherited Deafness.
Structure, 26, 2018
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1DPG
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6JFV
 | | The crystal structure of 2B-2B complex from keratins 5 and 14 (C367A mutant of K14) | | Descriptor: | Keratin, type I cytoskeletal 14, type II cytoskeletal 5 | | Authors: | Kim, M.S, Lee, C.H, Coulombe, P.A, Leahy, D.J. | | Deposit date: | 2019-02-12 | | Release date: | 2020-01-22 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly.
Structure, 28, 2020
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6AU5
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5EXG
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5VKG
 | | Solution-state NMR structural ensemble of human Tsg101 UEV in complex with tenatoprazole | | Descriptor: | 4-methoxy-1-(5-methoxy-3H-imidazo[4,5-b]pyridin-2-yl)-3,5-dimethyl-2-(sulfanylmethyl)pyridin-1-ium, Tumor susceptibility gene 101 protein | | Authors: | Strickland, M, Ehrlich, L.S, Watanabe, S, Khan, M, Strub, M.-P, Luan, C.H, Powell, M.D, Leis, J, Tjandra, N, Carter, C. | | Deposit date: | 2017-04-21 | | Release date: | 2017-11-15 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | Tsg101 chaperone function revealed by HIV-1 assembly inhibitors.
Nat Commun, 8, 2017
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6EY8
 | | Estimation of relative drug-target residence times by random acceleration molecular dynamics simulation | | Descriptor: | DIMETHYL SULFOXIDE, Heat shock protein HSP 90-alpha, SULFATE ION, ... | | Authors: | Musil, D, Lehmann, M, Buchstaller, H.-P. | | Deposit date: | 2017-11-11 | | Release date: | 2018-05-30 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.16 Å) | | Cite: | Estimation of Drug-Target Residence Times by tau-Random Acceleration Molecular Dynamics Simulations.
J Chem Theory Comput, 14, 2018
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2THI
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6JHI
 | | Crystal structure of mutant D470A of Pullulanase from Paenibacillus barengoltzii complexed with maltotetraose | | Descriptor: | CALCIUM ION, CHLORIDE ION, Pulullanase, ... | | Authors: | Wu, S.W, Yang, S.Q, Qin, Z, You, X, Huang, P, Jiang, Z.Q. | | Deposit date: | 2019-02-18 | | Release date: | 2019-03-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.319 Å) | | Cite: | Crystal structure of mutant D470A of Pullulanase from Paenibacillus barengoltzii complexed with maltotetraose
To Be Published
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4LN6
 | | The crystal structure of hemagglutinin from a h7n9 influenza virus (a/shanghai/2/2013) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Yang, H, Carney, P.J, Chang, J.C, Villanueva, J.M, Stevens, J. | | Deposit date: | 2013-07-11 | | Release date: | 2013-10-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.12 Å) | | Cite: | Structural Analysis of the Hemagglutinin from the Recent 2013 H7N9 Influenza Virus.
J.Virol., 87, 2013
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5EZO
 | | Crystal Structure of PfCyRPA in complex with an invasion-inhibitory antibody Fab. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, PfCyRPA, c12 FAB, ... | | Authors: | Favuzza, P, Pluschke, G, Rudolph, M.G. | | Deposit date: | 2015-11-26 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3.63 Å) | | Cite: | Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife, 6, 2017
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6JIQ
 | | Crystal structure of Streptococcus pneumoniae SP_0782 (residues 7-79) in complex with single-stranded DNA dT6 | | Descriptor: | DNA (5'-D(*TP*TP*TP*TP*T)-3'), SP_0782 | | Authors: | Fang, X, Lu, G, Li, S, Zhu, J, Yang, Y, Gong, P. | | Deposit date: | 2019-02-22 | | Release date: | 2019-11-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Structural insight into the length-dependent binding of ssDNA by SP_0782 from Streptococcus pneumoniae, reveals a divergence in the DNA-binding interface of PC4-like proteins.
Nucleic Acids Res., 48, 2020
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2FQ2
 | | Solution structure of minor conformation of holo-acyl carrier protein from malaria parasite plasmodium falciparum | | Descriptor: | 4'-PHOSPHOPANTETHEINE, acyl carrier protein | | Authors: | Sharma, A.K, Sharma, S.K, Surolia, A, Surolia, N, Sarma, S.P. | | Deposit date: | 2006-01-17 | | Release date: | 2006-08-08 | | Last modified: | 2022-03-09 | | Method: | SOLUTION NMR | | Cite: | Solution structures of conformationally equilibrium forms of holo-acyl carrier protein (PfACP) from Plasmodium falciparum provides insight into the mechanism of activation of ACPs
Biochemistry, 45, 2006
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5WEJ
 | | 1.95 A resolution structure of Norovirus 3CL protease in complex with a dipeptidyl oxazolidinone-based inhibitor | | Descriptor: | (2S)-2-{(5S)-5-[(3-chlorophenyl)methyl]-2-oxo-1,3-oxazolidin-3-yl}-4-methyl-N-{(2S)-1-oxo-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}pentanamide, Genome polyprotein | | Authors: | Lovell, S, Battaile, K.P, Mehzabeen, N, Damalanka, V.C, Kim, Y, Kankanamalage, A.C.G, Rathnayake, A.D, Nguyen, H.N, Chang, K.O, Groutas, W.C. | | Deposit date: | 2017-07-10 | | Release date: | 2017-12-13 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure-guided design, synthesis and evaluation of oxazolidinone-based inhibitors of norovirus 3CL protease.
Eur J Med Chem, 143, 2017
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5TKL
 | | Crystal structure of FBP aldolase from Toxoplasma gondii, condensation intermediate | | Descriptor: | 1,3-DIHYDROXYACETONEPHOSPHATE, 1,6-di-O-phosphono-D-fructose, Fructose-bisphosphate aldolase, ... | | Authors: | Heron, P.W, Sygusch, J. | | Deposit date: | 2016-10-06 | | Release date: | 2017-10-04 | | Last modified: | 2020-01-08 | | Method: | X-RAY DIFFRACTION (1.751 Å) | | Cite: | Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases.
J. Biol. Chem., 292, 2017
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5F1S
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6AVB
 | | CryoEM structure of Mical Oxidized Actin (Class 1) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle | | Authors: | Grintsevich, E.E, Ge, P, Sawaya, M.R, Yesilyurt, H.G, Terman, J.R, Zhou, Z.H, Reisler, E. | | Deposit date: | 2017-09-01 | | Release date: | 2018-01-17 | | Last modified: | 2019-11-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Catastrophic disassembly of actin filaments via Mical-mediated oxidation.
Nat Commun, 8, 2017
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3F32
 | | Horse spleen apoferritin | | Descriptor: | CADMIUM ION, Ferritin light chain, SULFATE ION | | Authors: | Vedula, L.S, Economou, N.J, Rossi, M.J, Eckenhoff, R.G, Loll, P.J. | | Deposit date: | 2008-10-30 | | Release date: | 2009-07-14 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A unitary anesthetic binding site at high resolution.
J.Biol.Chem., 284, 2009
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5T8A
 | | Recombinant cytotoxin-I from the venom of cobra N. oxiana | | Descriptor: | Cytotoxin 1 | | Authors: | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | Deposit date: | 2016-09-07 | | Release date: | 2017-09-20 | | Last modified: | 2019-05-08 | | Method: | SOLUTION NMR | | Cite: | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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6FD2
 | | Radical SAM 1,2-diol dehydratase AprD4 in complex with its substrate paromamine | | Descriptor: | 5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, METHIONINE, ... | | Authors: | Liu, W.Q, Amara, P, Mouesca, J.M, Ji, X, Renoux, O, Martin, L, Zhang, C, Zhang, Q, Nicolet, Y. | | Deposit date: | 2017-12-21 | | Release date: | 2018-01-17 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | 1,2-Diol Dehydration by the Radical SAM Enzyme AprD4: A Matter of Proton Circulation and Substrate Flexibility.
J. Am. Chem. Soc., 140, 2018
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1TW4
 | | Crystal Structure of Chicken Liver Basic Fatty Acid Binding Protein (Bile Acid Binding Protein) Complexed With Cholic Acid | | Descriptor: | CHOLIC ACID, Fatty acid-binding protein | | Authors: | Nichesola, D, Perduca, M, Capaldi, S, Carrizo, M.E, Righetti, P.G, Monaco, H.L. | | Deposit date: | 2004-06-30 | | Release date: | 2004-11-23 | | Last modified: | 2024-03-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of chicken liver basic Fatty Acid-binding protein complexed with cholic acid
Biochemistry, 43, 2004
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5F46
 | | Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample, apoenzyme form | | Descriptor: | CHLORIDE ION, aminoglycoside acetyltransferase meta-AAC0020 | | Authors: | Xu, Z, Skarina, T, Stogios, P.J, Yim, V, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2015-12-03 | | Release date: | 2015-12-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.
ACS Infect Dis, 3, 2017
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6F5S
 | | Crystal Structure of KDM4D with tetrazole ligand GF049 | | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Lysine-specific demethylase 4D, ... | | Authors: | Malecki, P.H, Link, A, Weiss, M.S, Heinemann, U. | | Deposit date: | 2017-12-02 | | Release date: | 2018-12-12 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.48 Å) | | Cite: | Crystal Structure of KDM4D with tetrazole ligand GF049
To be published
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1JAO
 | | COMPLEX OF 3-MERCAPTO-2-BENZYLPROPANOYL-ALA-GLY-NH2 WITH THE CATALYTIC DOMAIN OF MATRIX METALLO PROTEINASE-8 (MET80 FORM) | | Descriptor: | CALCIUM ION, MATRIX METALLO PROTEINASE-8 (MET80 FORM), N-[(2S)-2-benzyl-3-sulfanylpropanoyl]-L-alanylglycinamide, ... | | Authors: | Grams, F, Reinemer, P, Powers, J.C, Kleine, T, Piper, M, Tschesche, H, Huber, R, Bode, W. | | Deposit date: | 1996-03-11 | | Release date: | 1996-07-11 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design.
Eur.J.Biochem., 228, 1995
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6H2P
 | | Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and Cacodylate ligand | | Descriptor: | CACODYLATE ION, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Wilk, P, Piwowarczyk, R, Weiss, M.S. | | Deposit date: | 2018-07-14 | | Release date: | 2018-08-29 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (1.479 Å) | | Cite: | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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