5F46

Crystal structure of an aminoglycoside acetyltransferase meta-AAC0020 from an uncultured soil metagenomic sample, apoenzyme form

Summary for 5F46

• Entry DOI: 10.2210/pdb5f46/pdb
• Related: 5F47 5F48 5F49 5U08
• Descriptor: aminoglycoside acetyltransferase meta-AAC0020, CHLORIDE ION (3 entities in total)
• Functional Keywords: gnat fold, gcn5-n-acetyltransferase fold, acetyltransferase, aminoglycoside, antibiotic resistance, metagenome, soil, coenzyme a, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
• Biological source: uncultured bacterium
• Total number of polymer chains: 2
• Total formula weight: 37124.88

Authors

Xu, Z.,Skarina, T.,Stogios, P.J.,Yim, V.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2015-12-03, release date: 2015-12-16, Last modification date: 2023-09-27)

• Primary citation: Xu, Z.,Stogios, P.J.,Quaile, A.T.,Forsberg, K.J.,Patel, S.,Skarina, T.,Houliston, S.,Arrowsmith, C.,Dantas, G.,Savchenko, A.; Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.; ACS Infect Dis, 3:653-665, 2017; PubMed: 28756664; DOI: 10.1021/acsinfecdis.7b00068

Experimental method

X-RAY DIFFRACTION (1.85 Å)