4IS8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4is8 by Molmil](/molmil-images/mine/4is8) | |
3JVB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3jvb by Molmil](/molmil-images/mine/3jvb) | |
6G9E
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6g9e by Molmil](/molmil-images/mine/6g9e) | Crystal structure of immunomodulatory active chitinase from Trichuris suis - TsES1 - 6 molecules in ASU | 分子名称: | 1,2-ETHANEDIOL, Immunomodulatory active chitinase | 著者 | Malecki, P.H, Balster, K, Hartmann, S, Weiss, M.S, Heinemann, U. | 登録日 | 2018-04-10 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | A Helminth-Derived Chitinase Structurally Similar to Mammalian Chitinase Displays Immunomodulatory Properties in Inflammatory Lung Disease. J Immunol Res, 2021, 2021
|
|
6GAQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6gaq by Molmil](/molmil-images/mine/6gaq) | Crystal structure of oxidised Flavodoxin 2 from Bacillus cereus | 分子名称: | CALCIUM ION, FLAVIN MONONUCLEOTIDE, Flavodoxin, ... | 著者 | Lofstad, M, Gudim, I, Hersleth, H.-P. | 登録日 | 2018-04-12 | 公開日 | 2018-09-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Characterization of Different Flavodoxin Reductase-Flavodoxin (FNR-Fld) Interactions Reveals an Efficient FNR-Fld Redox Pair and Identifies a Novel FNR Subclass. Biochemistry, 57, 2018
|
|
2FTL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ftl by Molmil](/molmil-images/mine/2ftl) | Crystal structure of trypsin complexed with BPTI at 100K | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Cationic trypsin, ... | 著者 | Hanson, W.M, Horvath, M.P, Goldenberg, D.P. | 登録日 | 2006-01-24 | 公開日 | 2006-02-14 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Rigidification of a Flexible Protease Inhibitor Variant upon Binding to Trypsin. J.Mol.Biol., 366, 2007
|
|
4IA6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ia6 by Molmil](/molmil-images/mine/4ia6) | Hydratase from lactobacillus acidophilus in a ligand bound form (LA LAH) | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | 著者 | Khoshnevis, S, Neumann, P, Ficner, R. | 登録日 | 2012-12-06 | 公開日 | 2013-03-27 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure analysis of a fatty acid double-bond hydratase from Lactobacillus acidophilus Acta Crystallogr.,Sect.D, 69, 2013
|
|
8DQK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dqk by Molmil](/molmil-images/mine/8dqk) | Intermediate resolution structure of barley (1,3;1,4)-beta-glucan synthase CslF6. | 分子名称: | Cellulose synthase-like CslF6 | 著者 | Ho, R, Purushotham, P, Zimmer, J. | 登録日 | 2022-07-19 | 公開日 | 2022-11-30 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanism of mixed-linkage glucan biosynthesis by barley cellulose synthase-like CslF6 (1,3;1,4)-beta-glucan synthase. Sci Adv, 8, 2022
|
|
2YNN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ynn by Molmil](/molmil-images/mine/2ynn) | yeast betaprime COP 1-304 with KTKTN motif | 分子名称: | COATOMER SUBUNIT BETA', KTKTN MOTIF, SULFATE ION | 著者 | Jackson, L.P, Lewis, M, Kent, H.M, Edeling, M.A, Evans, P.R, Duden, R, Owen, D.J. | 登録日 | 2012-10-17 | 公開日 | 2012-12-12 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.782 Å) | 主引用文献 | Molecular Basis for Recognition of Dilysine Trafficking Motifs by Copi. Dev.Cell, 23, 2012
|
|
4JY7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jy7 by Molmil](/molmil-images/mine/4jy7) | Crystal structure of Acinetobacter baumannii Peptidyl-tRNA Hydrolase | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Yamini, S, Kaushik, S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. | 登録日 | 2013-03-29 | 公開日 | 2013-04-17 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Mode of Inhibitor Binding to Peptidyl-tRNA Hydrolase: Binding Studies and Structure Determination of Unbound and Bound Peptidyl-tRNA Hydrolase from Acinetobacter baumannii Plos One, 8, 2013
|
|
8TS0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ts0 by Molmil](/molmil-images/mine/8ts0) | |
4R31
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r31 by Molmil](/molmil-images/mine/4r31) | |
4JGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4jgx by Molmil](/molmil-images/mine/4jgx) | The Structure of Sterol Carrier Protein 2 from the Yeast Yarrowia Lipolytica | 分子名称: | CITRIC ACID, Fatty acid-binding protein, PALMITIC ACID | 著者 | De Berti, F.P, Capaldi, S, Acierno, J.P, Klinke, S, Monaco, H.L, Ermacora, M.R. | 登録日 | 2013-03-04 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The crystal structure of sterol carrier protein 2 from Yarrowia lipolytica and the evolutionary conservation of a large, non-specific lipid-binding cavity. J.Struct.Funct.Genom., 14, 2013
|
|
4I07
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4i07 by Molmil](/molmil-images/mine/4i07) | Structure of mature form of cathepsin B1 from Schistosoma mansoni | 分子名称: | ACETATE ION, CHLORIDE ION, Cathepsin B-like peptidase (C01 family) | 著者 | Rezacova, P, Jilkova, A, Brynda, J, Horn, M, Mares, M. | 登録日 | 2012-11-16 | 公開日 | 2014-02-05 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Activation route of the Schistosoma mansoni cathepsin B1 drug target: structural map with a glycosaminoglycan switch Structure, 22, 2014
|
|
6MSI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6msi by Molmil](/molmil-images/mine/6msi) | |
3M7N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m7n by Molmil](/molmil-images/mine/3m7n) | |
2CN1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2cn1 by Molmil](/molmil-images/mine/2cn1) | Crystal structure of Human Cytosolic 5'-Nucleotidase III (NT5C3) | 分子名称: | CYTOSOLIC 5'-NUCLEOTIDASE III | 著者 | Wallden, K, Stenmark, P, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Nilsson-Ehle, P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Uppenberg, J, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P. | 登録日 | 2006-05-17 | 公開日 | 2006-06-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal Structure of Human Cytosolic 5'-Nucleotidase II: Insights Into Allosteric Regulation and Substrate Recognition. J.Biol.Chem., 282, 2007
|
|
6VY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6vy0 by Molmil](/molmil-images/mine/6vy0) | |
8DTL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dtl by Molmil](/molmil-images/mine/8dtl) | Cryo-EM structure of insulin receptor (IR) bound with S597 peptide | 分子名称: | Insulin mimetic peptide S597, Insulin receptor | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | 登録日 | 2022-07-25 | 公開日 | 2022-09-07 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
|
|
3M2V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3m2v by Molmil](/molmil-images/mine/3m2v) | Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues | 分子名称: | 1,2-ETHANEDIOL, 1-THIOETHANESULFONIC ACID, ACETATE ION, ... | 著者 | Cedervall, P.E, Dey, M, Ragsdale, S.W, Wilmot, C.M. | 登録日 | 2010-03-08 | 公開日 | 2010-09-15 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues. Biochemistry, 49, 2010
|
|
1FLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1flo by Molmil](/molmil-images/mine/1flo) | FLP Recombinase-Holliday Junction Complex I | 分子名称: | FLP RECOMBINASE, PHOSPHONIC ACID, SYMMETRIZED FRT DNA SITES | 著者 | Chen, Y, Narendra, U, Iype, L.E, Cox, M.M, Rice, P.A. | 登録日 | 2000-08-14 | 公開日 | 2000-09-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Crystal structure of a Flp recombinase-Holliday junction complex: assembly of an active oligomer by helix swapping. Mol.Cell, 6, 2000
|
|
6JC5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jc5 by Molmil](/molmil-images/mine/6jc5) | |
8DTM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8dtm by Molmil](/molmil-images/mine/8dtm) | Cryo-EM structure of insulin receptor (IR) bound with S597 component 2 | 分子名称: | Insulin mimetic peptide S597 component 2, Insulin receptor | 著者 | Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E. | 登録日 | 2022-07-26 | 公開日 | 2022-09-07 | 最終更新日 | 2022-10-12 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Activation of the insulin receptor by an insulin mimetic peptide. Nat Commun, 13, 2022
|
|
6JCN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jcn by Molmil](/molmil-images/mine/6jcn) | Yeast dehydrodolichyl diphosphate synthase complex subunit NUS1 | 分子名称: | Dehydrodolichyl diphosphate synthase complex subunit NUS1, SULFATE ION | 著者 | Ko, T.-P, Ma, J, Liu, W, Chen, C.-C, Guo, R.-T. | 登録日 | 2019-01-29 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Structural insights to heterodimeric cis-prenyltransferases through yeast dehydrodolichyl diphosphate synthase subunit Nus1. Biochem.Biophys.Res.Commun., 515, 2019
|
|
8E61
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8e61 by Molmil](/molmil-images/mine/8e61) | Crystal structure of SARS-CoV-2 3CL protease in complex with a m-chlorophenyl dimethyl sulfane inhibitor | 分子名称: | (1R,2S)-2-{[N-({2-[(3-chlorophenyl)sulfanyl]-2-methylpropoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, (1S,2S)-2-{[N-({2-[(3-chlorophenyl)sulfanyl]-2-methylpropoxy}carbonyl)-L-leucyl]amino}-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 3C-like proteinase, ... | 著者 | Lovell, S, Liu, L, Battaile, K.P, Madden, T.K, Groutas, W.C. | 登録日 | 2022-08-22 | 公開日 | 2022-09-07 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure-guided design of direct-acting antivirals that exploit the gem-dimethyl effect and potently inhibit 3CL proteases of severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) and middle east respiratory syndrome coronavirus (MERS-CoV). Eur.J.Med.Chem., 254, 2023
|
|
4R4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r4j by Molmil](/molmil-images/mine/4r4j) | Crystal structure of complex sp_ASADH with 3-carboxypropyl-phthalic acid and Nicotinamide Adenine dinucleotide phosphate | 分子名称: | 1,2-ETHANEDIOL, 3-(3-carboxypropyl)benzene-1,2-dicarboxylic acid, Aspartate-semialdehyde dehydrogenase, ... | 著者 | Pavlovsky, A.G, Thangavelu, B, Bhansali, P, Viola, R.E. | 登録日 | 2014-08-19 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | A cautionary tale of structure-guided inhibitor development against an essential enzyme in the aspartate-biosynthetic pathway. Acta Crystallogr.,Sect.D, 70, 2014
|
|