8D9Y
 
 | | Crystal structure of Taipan alpha-neurotoxin in complex with Centi-3FTX-D09 antibody | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Centi-3FTX-D09 Fab heavy chain, ... | | 著者 | Pletnev, S, Verardi, R, Tully, E.S, Glanville, J, Kwong, P.D. | | 登録日 | 2022-06-12 | | 公開日 | 2023-06-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Venom protection by antibody from a snakebite hyperimmune subject
To Be Published
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4PFK
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3KCO
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6NDE
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6R5W
 | | Crystal structure of the receptor binding protein (gp15) of Listeria phage PSA | | 分子名称: | ACETATE ION, CADMIUM ION, Gp15 protein, ... | | 著者 | Dunne, M, Ernst, P, Pluckthun, A, Loessner, M.J, Kilcher, S. | | 登録日 | 2019-03-25 | | 公開日 | 2019-10-30 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins.
Cell Rep, 29, 2019
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7RHZ
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3KBN
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7RLX
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2YHU
 | | Trypanosoma brucei PTR1 in complex with inhibitor WHF30 | | 分子名称: | 3-(5-AMINO-1,3,4-THIADIAZOL-2-YL)-1-THIOPHEN-2-YLPROPAN-1-ONE, ACETATE ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Nerini, E, Dawson, A, Hunter, W.N, Costi, M.P. | | 登録日 | 2011-05-06 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery.
ACS Omega, 2, 2017
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7XFX
 | | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P. | | 登録日 | 2022-04-02 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.28 A resolution.
To Be Published
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7E48
 | | Crystal structure of InhA in complex with 3-nitropropanoic acid inhibitor | | 分子名称: | 3-NITROPROPANOIC ACID, Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL, ... | | 著者 | Songsiriritthigul, C, Hanwarinroj, C, Suttipanta, N, Kamsri, P, Kittakoop, P, Pungpo, P. | | 登録日 | 2021-02-10 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid.
Proteins, 90, 2022
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6FPT
 | | Crystal structure of Danio rerio Lin41 filamin-NHL domains | | 分子名称: | E3 ubiquitin-protein ligase TRIM71 | | 著者 | Kumari, P, Aeschimann, F, Gaidatzis, D, Keusch, J.J, Ghosh, P, Neagu, A, Pachulska-Wieczorek, K, Bujnicki, J.M, Gut, H, Grosshans, H, Ciosk, R. | | 登録日 | 2018-02-12 | | 公開日 | 2018-05-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
Nat Commun, 9, 2018
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7XFY
 | | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution. | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... | | 著者 | Maurya, A, Singh, P.K, Viswanathan, V, Sharma, P, Sharma, S, Singh, T.P. | | 登録日 | 2022-04-02 | | 公開日 | 2022-05-11 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | | 主引用文献 | Crystal structure of the ternary complex of Peptidoglycan recognition protein, PGRP-S with hexanoic and tartaric acids at 2.67 A resolution.
To Be Published
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8X4Z
 | | BA.2.86 Spike Trimer with ins483V mutation (3 RBD down) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.49 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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8X56
 | | BA.2.86 Spike Trimer with T356K mutation (1 RBD up) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Yue, C, Liu, P. | | 登録日 | 2023-11-16 | | 公開日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | | 主引用文献 | Spike N354 glycosylation augments SARS-CoV-2 fitness for human adaptation through structural plasticity
Natl Sci Rev, 2024
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8V6S
 | | Crystal structure of PcThsA in complex with Imidazole Adenine Dinucleotide | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-imidazol-1-yl-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, E, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
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6HDD
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8GJH
 | | Salmonella ArnA | | 分子名称: | Bifunctional polymyxin resistance protein ArnA, URIDINE-5'-DIPHOSPHATE-GLUCURONIC ACID | | 著者 | Sousa, M.C, Mitchell, M.E, Gatzeva-Topalova, P.Z. | | 登録日 | 2023-03-15 | | 公開日 | 2023-08-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Targeting the Conformational Change in ArnA Dehydrogenase for Selective Inhibition of Polymyxin Resistance.
Biochemistry, 62, 2023
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7ZO6
 | | L1 metallo-beta-lactamase in complex with hydrolysed cefoxitin | | 分子名称: | (2~{R},5~{S})-5-(aminocarbonyloxymethyl)-2-[(1~{S})-1-methoxy-2-oxidanyl-2-oxidanylidene-1-(2-thiophen-2-ylethanoylamino)ethyl]-5,6-dihydro-2~{H}-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... | | 著者 | Hinchliffe, P, Spencer, J. | | 登録日 | 2022-04-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | | 主引用文献 | Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J.Biol.Chem., 299, 2023
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8V6Q
 | | Crystal structure of EcThsA in ligand-free state | | 分子名称: | Thoeris protein ThsA Macro domain-containing protein | | 著者 | Shi, Y, Masic, V, Mosaiab, T, Goulart, C.C, Hartley-Tassell, L, Sorbello, M, Vasquez, V, Mishra, B.P, Holt, S, Gu, W, Kobe, B, Ve, T. | | 登録日 | 2023-12-02 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | | 主引用文献 | Structural characterization of macro domain-containing Thoeris antiphage defense systems.
Sci Adv, 10, 2024
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7ZO7
 | | L1 metallo-beta-lactamase in complex with hydrolysed cefmetazole | | 分子名称: | (2R,5R)-2-[(1S)-1-[2-(cyanomethylsulfanyl)ethanoylamino]-1-methoxy-2-oxidanyl-2-oxidanylidene-ethyl]-5-[(1-methyl-1,2,3,4-tetrazol-5-yl)sulfanylmethyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... | | 著者 | Hinchliffe, P, Spencer, J. | | 登録日 | 2022-04-24 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Interactions of hydrolyzed beta-lactams with the L1 metallo-beta-lactamase: Crystallography supports stereoselective binding of cephem/carbapenem products.
J.Biol.Chem., 299, 2023
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3KES
 | | Crystal structure of the autoproteolytic domain from the nuclear pore complex component NUP145 from Saccharomyces cerevisiae in the Hexagonal, P61 space group | | 分子名称: | 1,2-ETHANEDIOL, Nucleoporin NUP145 | | 著者 | Sampathkumar, P, Ozyurt, S.A, Do, J, Bain, K, Dickey, M, Gheyi, T, Sali, A, Kim, S.J, Phillips, J, Pieper, U, Fernandez-Martinez, J, Franke, J.D, Atwell, S, Thompson, D.A, Emtage, J.S, Wasserman, S, Rout, M, Sauder, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2009-10-26 | | 公開日 | 2009-12-22 | | 最終更新日 | 2021-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structures of the autoproteolytic domain from the Saccharomyces cerevisiae nuclear pore complex component, Nup145.
Proteins, 78, 2010
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8QZN
 | | DARPin-Armadillo fusion protein with a selected Tyrosin pocket binding to the fused target peptide | | 分子名称: | 1,2-ETHANEDIOL, DARPin-Armadillo fusion protein with Tyrosin pocket and linked target peptide, SULFATE ION | | 著者 | Stark, Y, Menard, F, Jeliazkov, J, Ernst, P, Chembath, A, Ashraf, M, Hine, A, Plueckthun, A. | | 登録日 | 2023-10-27 | | 公開日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules.
Proc.Natl.Acad.Sci.USA, 121, 2024
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6TSW
 | | Isometric capsid of empty GTA particle computed with I4(I,n25r) symmetry | | 分子名称: | Major capsid protein Rcc01687 | | 著者 | Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P. | | 登録日 | 2019-12-21 | | 公開日 | 2020-07-22 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (4.03 Å) | | 主引用文献 | Structure and mechanism of DNA delivery of a gene transfer agent.
Nat Commun, 11, 2020
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6HHO
 | | Crystal structure of RIP1 kinase in complex with GSK547 | | 分子名称: | 6-[4-[(5~{S})-5-[3,5-bis(fluoranyl)phenyl]pyrazolidin-1-yl]carbonylpiperidin-1-yl]pyrimidine-4-carbonitrile, Receptor-interacting serine/threonine-protein kinase 1 | | 著者 | Thorpe, J.H, Harris, P.A. | | 登録日 | 2018-08-28 | | 公開日 | 2018-12-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.49 Å) | | 主引用文献 | RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer.
Cancer Cell, 34, 2018
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