7E48
Crystal structure of InhA in complex with 3-nitropropanoic acid inhibitor
Summary for 7E48
Entry DOI | 10.2210/pdb7e48/pdb |
Related | 6R9W |
Descriptor | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, 3-NITROPROPANOIC ACID, ... (5 entities in total) |
Functional Keywords | enoyl-acp reductase, fas-ii enoyl-acp reductase, nadh- dependent 2-trans-enoyl-acp reductase, oxidoreductase |
Biological source | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
Total number of polymer chains | 4 |
Total formula weight | 117441.22 |
Authors | Songsiriritthigul, C.,Hanwarinroj, C.,Suttipanta, N.,Kamsri, P.,Kittakoop, P.,Pungpo, P. (deposition date: 2021-02-10, release date: 2021-11-24, Last modification date: 2023-11-29) |
Primary citation | Songsiriritthigul, C.,Hanwarinroj, C.,Pakamwong, B.,Srimanote, P.,Suttipanta, N.,Sureram, S.,Suttisintong, K.,Kamsri, P.,Punkvang, A.,Spencer, J.,Kittakoop, P.,Pungpo, P. Inhibition of Mycobacterium tuberculosis InhA by 3-nitropropanoic acid. Proteins, 90:898-904, 2022 Cited by PubMed: 34677871DOI: 10.1002/prot.26268 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
Download full validation report